I study floppy proteins and teach students who are incarcerated | https://xitter.cf/t.co/IEka0gToDJ

St Louis, MO
Joined June 2019
Matthew Ryan King retweeted
Congratulations to @DanaFarber's Cigall Kadoch, PhD, (@CKadoch) who was named as the Laureate of the Blavatnik National Awards for Young Scientists today. The prestigious award from @BlavatnikAwards and @NYASciences (cont) ms.spr.ly/l/6014mOVe0
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Congratulations to Avnika Pant on receiving a scholarship & invitation to attend the @MBLScience Physiology program this summer! This selective and intensive program is one of the oldest continually running biology courses. Avnika is a doctoral student with @PappulabWashU.
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Matthew Ryan King retweeted
Congrats to @sophiembtravis and team from @RuiZhangWUSTL and @LabPetry on the augmin structure! Also congrats to @PfefferCryoLab and @lchangpurduebio for their structural work!
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Happy to present a new preprint from @MarileenD’s lab, in which we ask if a microtubule plus-end tracking comet is held together by interactions that also drive phase separation. The answer is not a clear ‘yes’ or ‘no’, so here goes the 🧵1/10
Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus ends biorxiv.org/cgi/content/shor…
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Matthew Ryan King retweeted
At some point you have to admit that doing things ironically can have very straightforward consequences. #FakeAccountsClub @laurenoyler
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Matthew Ryan King retweeted
Beautiful work officially out by @SagarSetru, Bernardo deGouveia, Josh @shaevitz and Howard Stone - a tri-departmental @Princeton collaboration. What do drops on spiderwebs and protein droplets on microtubules have in common? #PhaseSeparation on Cellular Surfaces
A hydrodynamic instability drives protein droplet formation on microtubules to nucleate branches go.nature.com/39oh79J
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Once again: DO NOT TRACK THE NUMBER OF CASES. THIS IS SUPPOSED TO INCREASE AS TESTING COMES ONLINE. Instead, track the number of deaths per day. If the "doubling time" of these slows to more than 3 days, we're starting to bend the curve. thread: xitter.cf/SamWangPhD/status/1241…
Bookmark this. When the doubling time of deaths* gets above 3 days, we will have begun to get past the runaway period of the pandemic. Note the current doubling times for China (35 days) & South Korea (12 days). *not cases, which can be underdiagnosed ourworldindata.org/coronavir…
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Matthew Ryan King retweeted
As promised, here is our first glimpse of the #COVID19 spike protein (aka the demogorgon) in action, courtesy of @foldingathome . More to come!
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Matthew Ryan King retweeted
Non-spherical coacervates are cool! I was wondering when this would be coming out. Congrats @luiree and Kasper!
PNPase mediated UDP Polymerization leads to non-isotropic Poly(U) * Spermine Coacervate Growth. High phosphate levels drive Poly(U) Depolymerization & Coacervate Dissolution. By @luiree & @MarileenD. Now in Langmuir: pubs.acs.org/doi/abs/10.1021…
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Matthew Ryan King retweeted
In a paper just published Rohit Pappu’s and my lab show that the number of stickers and their patterning determine LLPS of prion-like LCDs. Our findings lead to a numerical model that enables the prediction of full binodals from the sequence. science.sciencemag.org/conte… (1/15)
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Matthew Ryan King retweeted
Come explore the Physics of Life. A summer school for advanced undergraduates. We have space for 24 students, with all local expenses covered and no tuition or fees. biophysics.princeton.edu/edu…
Matthew Ryan King retweeted
#BigWeek for @LabPetry: Two of our papers came out at the same time. Congrats to @MatthewRKing1 for one paper and @AcoAlfaro and @AkankshaThawani for the second paper. Both heroic work by the two first graduate students of the lab #littledidweknow #proudPI
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Matthew Ryan King retweeted
Enzymatic activity induces transient non-spherical coacervate shapes biorxiv.org/cgi/content/shor… #bioRxiv
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Terrific end to an amazing Physiology rotation! In two weeks, we found how #marine and xenopus #microtubules are made, poked on microtubules coated with proteins and studied how microtubule structures change with encapsulation and proteins! @MBLScience @MBLPhys
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Matthew Ryan King retweeted
The @PrincetonMolBio dept @Princeton invites applications in #Virology and Host-Virus Interactions for a tenure-track faculty position at the Assistant Professor level. I strongly encourage every qualified candidate to consider applying, puwebp.princeton.edu/AcadHir… . Please retweet!
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This week we isolated tubulin from the Woods Hole squid to study how #marine #microtubules grow and function. Gorgeous squid microtubules seen and the process was captured with the fabulous drawings by Oliver Hoeller oliverhoeller.com/ @MBLPhys @MBLScience @LabPetry
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