@GraceSchaack
Joined October 2018
  • Tweets50
  • Following154
  • Followers102
4Media
Happy Match Day! #MatchDay2024 @andrew_sung @mochoimmuno @bopenglear @LauraSteenberge @mitojondrion (photo credit to Bo/Kyle)
UW MSTP (University of Wisconsin-Madison)@UWMSTP16 Mar 2024
Congratulations to the class of 2024! #MatchDay2024
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Grace Schaack retweeted
Mehle Lab@MehleLab8 Jun 2023
It's been a busy work for the lab. Thomas (holding 🍾) passed his @UWMadisonMDTP qualifying exam with aplomb. Very excited to see him tackle his project as a dissertator. Congrats Thomas.
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Finally a gift to rival the ceremonial swords given by some unis
Mehle Lab@MehleLab6 Jun 2023
Excited to announce the successful thesis defense by newly minted Dr. @graceschaack (seen riding her thesis gift, a T-Rex). Great public presentation and closed-door defense. Super proud to have her as a lab alumna, and returning to the clinic to complete her MD. Congrats!
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Congratulations to CMB student, Rodrigo Ibarra, whose presentation won 1st place at the Fulbright Seminar in Boston!
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Grace Schaack retweeted
Rachel Cueny@rachel_cueny31 Mar 2023
Thrilled to share that our review on bacterial G-quadruplexes is now online! Thankful for my lab mate and friend @SarahMcMillan05 who wrote this review with me! tandfonline.com/doi/full/10.…

G-quadruplexes in bacteria: insights into the regulatory roles and interacting proteins of non-ca...

G-quadruplexes (G4s) are highly stable, non-canonical DNA or RNA structures that can form in guanine-rich stretches of nucleic acids. G4-forming sequences have been found in all domains of life, an...

tandfonline.com
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Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks @kaaamato @mehlelab @tcflab @UWMadisonMMI #influenza #flu #virology go.nature.com/3PqiuXw
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New preprint📢 We created *really* diverse libraries of barcoded #influenza viruses & used them to track viruses in hosts. We found multiple narrow within-host bottlenecks → genetically distinct "islands" of infection in a single host. Check it out⬇️ biorxiv.org/content/10.1101/…

Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlen...

Transmission of influenza A viruses (IAV) between hosts is subject to numerous physical and biological barriers that impose genetic bottlenecks, constraining viral diversity and adaptation. The...

biorxiv.org
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Grace Schaack retweeted
Mehle Lab@MehleLab29 Sep 2021
What factors shape evolution of influenza virus within an individual? Happy to share our collaborative work led by @kaaamato with Luis and Kat and @tcflab, @SSCLabQuips, and @KoelleLab that shows genetic bottlenecks restrain intrahost influenza virus evolution. 1/10
bioRxiv@biorxivpreprint29 Sep 2021
Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks biorxiv.org/cgi/content/shor… #bioRxiv
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Grace Schaack retweeted
Baker Lab@BakerLabLBRI7 Sep 2021
Hello world! The Baker Lab is opening in mid October, 2021 at @LovelaceBio in ABQ, NM. Excited to keep serving up research on influenza, host-switch, and alternative RNA splicing. Actively recruiting an experienced technician & postdoc: thebakerlab.com/opportunitie… #LoveVirology
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Grace Schaack retweeted
Mehle Lab@MehleLab19 Jul 2021
Excited for the lab to present our latest at #ASV2021. intra-host transmission dynamics by @kaaamato W13-7; and host factors by @BakerVirusMaker W34-6, @GraceSchaack W34-8, @casonthemason W34-9.
Mehle Lab workshops 13-7, 34-6, 34-8, 34-9.

ALT Mehle Lab workshops 13-7, 34-6, 34-8, 34-9.

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Questions about COVID-19 vaccines? Get answers at free COVID-19 Vaccine Education Town Halls sponsored by American Society for Virology and American Society for Microbiology. Please RT and share widely asv.org/education @ASMicrobiology
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Mehle Lab@MehleLab10 Nov 2020
New work led by @BakerVirusMaker: What happens when host cells dual purpose critical genes with cryptic antiviral function? Viruses are forced to “choose” between two bad options – suffer the antagonism or attack the essential gene and limit resources to make progeny. 👇🧵1/7
bioRxiv Microbiology@biorxiv_micrbio10 Nov 2020
Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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So excited it's finally in print! We worked hard to characterize patterns of #SARSCoV2 transmission in Wisconsin this past spring. Check out what we found here⬇️ @GageKMoreno @KasenRiemersma @tcflab @dho 1/
This Post is from an account that no longer exists. Learn more
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Grace Schaack retweeted
Mehle Lab@MehleLab7 Oct 2020
Fantastic news for a fantastic scientist, mentor and leader with vision @doudna_lab. An amazing pair.
The Nobel Prize
@NobelPrize7 Oct 2020
BREAKING NEWS: The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
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We want to reach even more early-college and high school students to let them know about programs and careers in #research and #medicine. Let us know how we can connect! #diversityinSTEM #IndigenousInSTEM #BlackInSTEM #LatinosInSTEM #LGBTQInSTEM #WomenInSTEM #DisabledinSTEM
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Mehle Lab@MehleLab4 Sep 2020
Our paper is now live at PLOS Pathogens. Several new polymerase structures came out since we submitted, and we were happy include these and discuss the potential impact of phosphorylation, especially on template exit channel formation. journals.plos.org/plospathog…

Phosphorylation controls RNA binding and transcription by the influenza virus polymerase

Author summary The influenza virus polymerase is a multifunctional enzyme directing viral gene expression and genome replication. Immediately following infection, the polymerase primarily performs...

journals.plos.org
Mehle Lab@MehleLab11 Feb 2020
Replying to @HypemanPhD
@PUNusualSuspect makes our next step in understanding how phosphorylation directly controls the influenza virus polymerase. Spoiler alert - we find a phosphosite that specifically represses transcription while leaving replication intact. Great collaboration with Coon lab again.
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Grace Schaack retweeted
Mehle Lab@MehleLab24 Aug 2020
Excited for our paper on influenza virus and IFIT2 now at @NatureMicrobiol : A mystery in 3 parts where things aren’t always what they seem. It has something for everyone, with CRISPR screens, CLIP-Seq, ribosome profiling, and ribosome pausing. 1/n nature.com/articles/s41564-0…
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We have been working hard to characterize #SARSCoV2 in #Wisconsin, USA. Our work is being peer reviewed now, but our preprint is available here: medrxiv.org/content/10.1101/… Here is what we have learned about #SARSCoV2 in WI: THREAD (1/8) @GageKMoreno

Distinct patterns of SARS-CoV-2 transmission in two nearby communities in Wisconsin, USA

Evidence-based public health approaches that minimize the introduction and spread of new SARS-CoV-2 transmission clusters are urgently needed in the United States and other countries struggling with...

medrxiv.org
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Just out: preprint of study on face covering use in WI grocery stores during #COVID-19 shows only 41.2% of people wearing masks, need for interventions to ⬆️use. By entire 1st-year @uwsmph @UWMSTP cohort w/mentoring from Dr. Nasia Safdar. Read & comment: ow.ly/dvYM50AcFS5
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Grace Schaack retweeted
Mehle Lab@MehleLab18 Jun 2020
Does #ASV2020 have you even more excited for virology? Love working with a fun team? Love creative science? Love owning your project and career development? Love puns? (OK, maybe the thing about puns isn't required). DM, see attached or check mehlelab.com.
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