Clinician Scientist. Cardiovascular genetics, genomics in healthcare, inherited cardiac conditions, open science, patient participation. He/him. @CVGenomics
London , UK
Joined March 2011
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I've seen @ATJCagan’s great illustrations across twitter, but first time I’ve benefitted from this unique feedback - good test of whether intended key messages come across to a new audience. And a fun visual summary of my programme. Thanks to @wellcometrust & @ATJCagan.
James Ware retweeted
Low penetrance sarcomere variants (LowSVs) contribute to mild HCM alone but increase severity with high-risk variants. @neallakdawala @drjamesware @tikuowens @jodieingles27 @S2beri @sday_hcm @SeanLZheng @AdamHelmsMD ahajournals.org/doi/abs/10.1…
James Ware retweeted
Today we introduce a new drug candidate for prion disease: a PrP-lowering divalent siRNA. A 4-year collaboration with @RTI_UMassChan enabled by @NINDSfunding IGNITE & URGenT mechanisms. biorxiv.org/content/10.1101/…
Our hope is to advance this to the clinic, wish us luck!
James Ware retweeted
We're looking for a research nurse to join our team and work on the SMARTER-Cardiomyopathy Study
imperial.ac.uk/jobs/search-j…
James Ware retweeted
We’re really excited to focus on understanding takotsubo cardiomyopathy. Have your say and take part in research to help us find the causes, risks, and treatments 💪🫀🧬@Cardiomyopathy @TheBHF @BHFNI @BHFScotland @BHFCymru @GlobalHeartHub
We want to learn more about the genetics of Takotsubo cardiomyopathy.
Are you over 18, in the UK and interested in taking part in research?
Go to thehearthive.org to learn more about the Heart Hive Cardiomyopathy Study
#takotsubo #cardiomyopathy
It turns out much needed huge international efforts on dilated cardiomyopathy are like buses... nature.com/articles/s41588-0… nature.com/articles/s41588-0…
See threads:
xitter.cf/KrishnaAragam/status/1…
xitter.cf/SeanLZheng/status/1859…
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James Ware retweeted
Maybe everyone already knew about this, but the @AllofUsResearch results browser is up so you can look up your favorite genetic associations (I assume this is the browser @konradjk presented at #ASHG24 that is now ready?).
allbyall.researchallofus.org…
James Ware retweeted
Closing on the 24th of November is a bioinfomatics Technician position in the @CVGenomics group led by @DrJamesWare
lms.mrc.ac.uk/vacancies/rese…
Fully funded PhD studentships @MRC_LMS to start next year. One of the openings is in my team @CVGenomics if cardiovascular genomics and/or data science for precision healthcare is your thing. And a fantastic line up of other opportunities if you interests lie elsewhere...
There are 4-year studentship available at the LMS for October 2025! Deadline is 11th of December
lms.mrc.ac.uk/study-here/phd…
Last chance for this - deadline tomorrow…
Are you a good communicator, interested in empowering patients to participate in research and contribute to the research agenda, and wanting to have an impact? Come and join us... @thehearthive @Cardiomyopathy @MRC_LMS @ImperialNHLI
James Ware retweeted
📢3-year postdoctoral fellow position available
Interested in gene regulation and deciphering the molecular mechanisms of human disease, join us at the @MRC_LMS in the beautiful city of London
For more details, please visit lms.mrc.ac.uk/vacancies/mrc-…
✉️[email protected]
🙏RT
James Ware retweeted
Automating AI research is exciting! But can LLMs actually produce novel, expert-level research ideas?
After a year-long study, we obtained the first statistically significant conclusion: LLM-generated ideas are more novel than ideas written by expert human researchers.
Congratulations Karen... It is a privilege to share an institute with impactful innovators like you. I will resist puns on shining example / basking in reflected glory etc etc
📢: Congratulations to our @MRC_LMS @imperialcollege group head, Dr Karen Sarkisyan on being named as one of @MIT @techreview "35 Innovators Under 35" 2024! 🎉🎉🎉
lms.mrc.ac.uk/mrc-lms-resear…
James Ware retweeted
👉 Delighted to share our study evaluating the added value of scar quantification for arrhythmic risk prediction in non-ischaemic cardiomyopathy
@JACCJournals @escardio @ESCardioNews
doi.org/10.1016/j.jacc.2024.…
Are you a good communicator, interested in empowering patients to participate in research and contribute to the research agenda, and wanting to have an impact? Come and join us... @thehearthive @Cardiomyopathy @MRC_LMS @ImperialNHLI
We have an exciting opportunity to join our team and the @thehearthive project.
Engage with participants, grow our platform, build online studies and work with our close partners to help make a difference for heart health
imperial.ac.uk/jobs/search-j…
James Ware retweeted
And he’s done it again 💪 @SeanLZheng wins the Population Science, Genetics and Epidemiology Young Investigator Award at ESC! 🥂Two years in a row at ESC! 🏆🏆@drjamesware @tomlumbers @AH_AlbertHenry @HERMESgenetics @ImperialNHLI @CVGenomics @TheBHF
Congrats to young scientists presenting in Young Investigator Award Session in Pop Science, Genetics and Épi at #ESCCongress2024 - a fantastic session. Of course I’m rooting for our own @SeanLZheng @CVGenomics, but it’s a great line up and all are winners
James Ware retweeted
A fantastic first day at #ESCCongress2024 - great presentations by Ishika, Ewa, @DrRosemaryKirk , @AH_AlbertHenry & great discussions had! @doctor_paz @roddywalsh @LaraACurran 🫀🧬
James Ware retweeted
🥳Our work on missense constraint on homologous residues has been published in Genome Medicine.
Zhang and coll. introduce HMC, Homologous Missense Constraint score, as a novel and accurate predictor of missense consequence for improved variant interpretation
@xiaolei_gene @nickywhiffin @drjamesware
genomemedicine.biomedcentral…
