@AdamHelmsMD

Genetic Cardiologist at University of Michigan

 Ann Arbor, MI
Joined January 2020
  • Tweets13
  • Following38
  • Followers133
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Proud to see this world wide effort for #DSP finally out! Kudos to my DSP-erados partner @RTCarrick for bringing this paper home and thanks to the many collaborators @ProtonotariosA @HughCalkinsMD @LaredoMikael @AdamHelmsMD @vnparikh @jpvantintelen @teRieleA @JuliaCTourigny
🕊️Fran Bermúdez-Jiménez ن@FranBermudz16 Jul 2024
Arrhythmogenic Cardiomyopathy Risk 🧬 #Genetics #HeartHealth #Research New study introduces a tool to assess arrhythmic risk in DSP gene variant carriers @ehj_ed academic.oup.com/eurheartj/a…

A novel tool for arrhythmic risk stratification in desmoplakin gene variant carriers

AbstractBackground and Aims. Pathogenic desmoplakin (DSP) gene variants are associated with the development of a distinct form of arrhythmogenic cardiomyop

academic.oup.com
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Adam Helms retweeted
Circulation@CircAHA2 Nov 2022
#OriginalResearch In mice models, dysfunction adhesion was demonstrated to play a key role in the pathophysiology of arrhythmogenic cardiomyopathy #AHAJournals ahajrnls.org/3Nyu57q
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Like everything else she writes, a must read in @JACCJournals #JACCHF from @AG_EM33 💙💚 Critical Importance of Genetic Screening in Family Members #cvGenetics jacc.org/doi/epdf/10.1016/j.…
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Outstanding @jclinicalinvest review about novel myosin-based interventions! @jct_ucb @sday_hcm JCI - Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure jci.org/articles/view/148557…
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Excited to share some new work from us today on ultra-rapid genome sequencing for the diagnosis of critically ill children and adults. In critical care settings, genetic diagnosis can shorten stays, direct precision therapy, save money, and help with family planning. 1/
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In this randomized phase 2 trial, Valsartan improved cardiac structure and function in patients with early-stage sarcomeric HCM compared to placebo. @NatureMedicine @glimongelli @Fedeilardi @FGraziani_Grace @IacopoOlivotto @saramoscatelli7 @PeroneFrancesco nature.com/articles/s41591-0…
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Excited to share our work on iPSC-derived 2D cardiac muscle bundles. Accessible and reproducible contractile assessment, insights on cardiac development, disease modeling. Read @NatureComms rdcu.be/cz3pD @BakerLaboratory @LoriLIsom1 @yuweiwu_imb @umichCVC
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Super excited to release genebass.org, a web application for browsing association results for 3,700 phenotypes across 281,850 individuals from the UK Biobank. The site features plots, tables, and controls for exploring billions of associations.
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Our paper on “The genetic architecture of Plakophilin 2 cardiomyopathy” is now online at @GIMJournal. Please check it out (and/or read the thread below) at rdcu.be/cmqCE ! 1/n
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⚡Out today from @ChrisMHaggerty + team: Clinical Findings and Diagnostic Yield of Arrhythmogenic Cardiomyopathy through Genomic Screening of Pathogenic Desmosome Gene Variants ahajournals.org/doi/abs/10.1… @AHAScience #ahajournals #cardiogen 📽️@JeanetteErdmann @AnwarChahal
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Adam Helms retweeted
Circulation@CircAHA14 Feb 2021
EXPLORER-HCM CMR substudy finds that mavacamten favorably impacts cardiac structure in obstructive HCM. Read more: ow.ly/Iobx50DxLH0 #AHAJournals @S2beri
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Grateful to work with @EricSmithMD & outstanding collaborators incl @neallakdawala @DanielJacobyMD @emmcnally @LWilsbacher @AubertGregory. Great to see recurring themes in others just out @piriou_nicolas et al @ESC_Journals, Poller et al @JAHA_AHA, Gandjbakhch et al @Circ_Gen
Circulation@CircAHA12 Jun 2020
Desmoplakin Cardiomyopathy: A fibrotic & inflammatory form of cardiomyopathy distinct from typical #ARVC. Read more: #AHAJournals ow.ly/eTkn50A1WAs @AdamHelmsMD @umichCVC @DanielJacobyMD @VorovichHeartMD
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