Zach Schafer's Lab @NotreDame. Studying #metabolism, #celldeath, #ECMdetachment, #metastasis, & #cancer. Account maintained by Zach. Views are mine.
Notre Dame, IN
Joined May 2018
- Tweets1.1K
- Following791
- Followers1.1K
- Likes2.2K
Schafer Lab retweeted
Our latest paper with Joan @BruggeMe is now out @NatureGenetics! We explore hidden mechanisms of BRCA1 hereditary breast cancer using new mouse models, revealing unexpected tumor-like chromatin changes in Brca1-heterozygous normal mammary cells.
nature.com/articles/s41588-0…
Schafer Lab retweeted
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
Schafer Lab retweeted
Please RT and help us get the word out. Scott Dixon @sjd956 and I are co-organizing the first @FASEBorg #Ferroptosis conference this summer! Awesome line up of speakers and room for additional short talks! Save the date & come join us July 27 - 31, 2025! 🤩events.faseb.org/event/11797…
ALT FASEB Ferroptosis Conference!
Schafer Lab retweeted
#NASmember Joan Brugge has advanced #breastcancer research in two major ways: through her studies of the processes in breast cancer's initiation and progression, and her explorations of how cellular receptors regulate the intracellular cytoskeleton. #BreastCancerAwarenessMonth
Schafer Lab retweeted
There is no such thing as a perfect leader.
In fact, if someone claims to be a perfect leader, they are probably not even a good leader, as they lack the self-awareness needed to seek out feedback and continue to grow and improve.
Schafer Lab retweeted
What an excellent meeting. Midwest has the best Metabolism 💪🏼
Thanks to @bensahralab, Nav, & Clara (@NorthwesternMed, @LurieCancer) for hosting. See ya next year in Ann Arbor!
@UMich represent 👇🏼〽️ #GoBlue
@YatrikShahLab, @DanWahlMD, @DNagrathLab
We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
Schafer Lab retweeted
We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
Schafer Lab retweeted
The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology.
Come be a colleague! More information here:
apply.interfolio.com/152596
Please share and retweet!
Schafer Lab retweeted
🥉 BRONZE
2021 biochemistry alum Yared Nuguse finished third in the men's 1500m, earning his first Olympic medal!
#ParisOlympics
Schafer Lab retweeted
Mark your calendars! The 1st FASEB #Ferroptosis conference, July 27-31 2025! We just posted our preliminary agenda! Spectacular line up and lots of space for short talks / late breaking speakers. Help us get the word out & come join us in 2025! @FASEBorg
events.faseb.org/event/11797…
Schafer Lab retweeted
This study, led by @alfmireles and published in @NatureComms, suggests that catheterized patients given antifibrinolytic medications—drugs that discourage bleeding—could be at a higher risk for developing a catheter-associated urinary tract infection.
bit.ly/4aHY5aN
ALT A polymicrobial infection in a catheterized bladder. Image taken by the Flores-Mireles Lab.
Schafer Lab retweeted
According to a research article in @CellReports, cancer cells with high levels of Acod1, located in the mitochondria, were discovered to decrease the effectiveness of a certain type of cancer therapy called immune checkpoint inhibitor therapy.
bit.ly/3UTFr9M
ALT Electron micrograph of mitochondria (pink/purple color) from cancer cells resistant to immune checkpoint inhibitors
Schafer Lab retweeted
𝟐𝟎𝟐𝟒 𝐍𝐀𝐓𝐈𝐎𝐍𝐀𝐋 𝐂𝐇𝐀𝐌𝐏𝐒!
The Fighting Irish go back-to-back with a dominating performance to capture the 2nd title in program history!
#GoIrish ☘️
Schafer Lab retweeted
An enzyme in cancer cells called aconitate decarboxylase (Acod1) appears to cause the release of short chains of amino acids, called peptides, that interfere with the way our bodies’ immune cells fight the disease, a new study by @ZTSlab shows.
bit.ly/3UTFr9M
ALT Electron micrograph of mitochondria (pink/purple color) from cancer cells resistant to immune checkpoint inhibitors
Schafer Lab retweeted
Excited to share that I'll be joining the Department of Chemistry and Biochemistry at the University of @NotreDame as a Huisking Foundation Assistant Professor in January 2025! My lab will develop chemical tools to retrain our immune system in cancer, autoimmunity, and more.
Schafer Lab retweeted
Thrilled to share that my thesis work on #ferroptosis is now live on @biorxivpreprint!
Here in the @YatrikShahLab we show that RSL3 is a non-selective inhibitor of the Selenoproteome, revealing new therapeutic opportunities in #colorectalcancer
biorxiv.org/content/10.1101/…
Schafer Lab retweeted
This symposium on #celldeath and survival will discuss exciting developments in this field including inflamed tissues and non-canonical #molecularpathways. Register for #Pathobiology2024 to attend this session! bit.ly/3TndnfK
@Penn @TuftsUniversity @NotreDame @YaleMed
