Scientist and Professor at University of Notre Dame; Father and Husband at House of Smith. opinions are my own.
Joined October 2014
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Thanks @stevens1lab for the encouragement to post! Click below to learn more about the advocacy logo we made in fall 2019, why we made it, why, now more than ever, we proudly display it and why we hope you display it too! 👇👇
Special thanks to @FChrisBennett and @nachoriko for the wonderfully written primer on our new microglia cannibalism publication. It’s so amazing when such exceptional scientists write about our work!
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
We are excited that our work describing microglia cannibalism is now officially in press! journals.plos.org/plosbiolog…
Stay tuned because we are on to the genetic mechanisms! 😀
For more information about the study, please see this thread: xitter.cf/cssmity/status/1636467…
Really excited about our new preprint from the lab about microglia lifespan and cannibalism. Congrats to Hannah Gordon for her hard work! Read more below about the story 👇🧵👇 @ZTSlab
biorxiv.org/content/10.1101/…
Microglia cannibalism!!!!
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
Come join us at Notre Dame!
Neuroscience faculty job alert! The University of Notre Dame is hiring 5 tenure-track positions in cellular, molecular, or computational neurobiology. Come be my colleague in a welcoming and inclusive environment. Please share! apply.interfolio.com/152596
The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology.
Come be a colleague! More information here:
apply.interfolio.com/152596
Please share and retweet!
We are seeking researchers who investigate the development, regeneration, and function of the nervous system, as well as the molecular and cellular mechanisms underlying health and disease, detection, and treatment.
I am excited to get this project moving with @stevens1lab to find new microglia modifiers. I am also excited to be part of the larger group of collaborative people that are in the @ChanZuckerberg network!
💡 Innovation + 👩🏾🔬🧑🏼🔬 Collaboration = 🧠 Increased understanding of the brain
Meet 64 interdisciplinary teams working to expand our understanding of neuroscience + find treatments for neurodegenerative diseases czi.co/42K4IqJ
I am excited for our most recent publication led by Jake Brandt (now postdoc with @SD_Ackerman). Jake's work reveals spontaneous activity in DRG glia in the early phases of its assembly. Interestingly to us, a part of the activity was dependent on mechanical channels. 🧵👇
.@cssmity &co show that satellite #GlialCells in the #PNS display isolated spontaneous Ca2+ transients, sensitive to #mechanosensitive protein #Piezo1, revealing a role for #mechanobiology in the activity of developing neural cells #PLOSBiology plos.io/3t0Ko6w
Jake's contribution to the lab was so important for our future work! In particular, he introduced calcium imaging to the lab, which opens up our ability to do circuit analysis (coming soon!)!
Finally, Jake made a personal dream come true...we somehow snuck in a Star Wars reference to our research! Next up, legos! media.giphy.com/media/UsmcxQ…
R01’s are so hard for me to write. They have to be so safe and conservative and I just do not think about science that way. We need more mechanisms like DP2s and more accessible R35s. Imagine what we could do if we didn’t spend so much time writing low risk stuff.
Thanks @TheFrancoLab for hosting me @CUAnschutz to talk about our work on microglia! What a great group of PIs and trainees in an exceptionally collegial environment. You also can’t top the views!
It is simply the best part of my job when one of the lab members gets a well deserved award or publication! Congrats to Camden for her hard work and perseverance! 👏🎉🥳🍻👏 @NDBios @NDscience @UNDResearch
I am officially an awardee of the NIH F31 diversity grant!
The funds will be used to investigate the colonization and differentiation of embryonic microglia.
Thank you to @cssmity, my committee, and all the awesome scientists who have listened to me ramble, we did it!!