Zach Schafer's Lab @NotreDame. Studying #metabolism, #celldeath, #ECMdetachment, #metastasis, & #cancer. Account maintained by Zach. Views are mine.
Notre Dame, IN
Joined May 2018
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Grateful to share our most recent paper--just published in @CellReports. The study was led by @NDBios PhD student @Schofield_isle, who will be defending his dissertation later this week. Also want to highlight @NotreDame senior and @NDXCTF athlete @EmmaAlbano4 as a co-author!
Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides dlvr.it/T4fW7f
Schafer Lab retweeted
Our latest paper with Joan @BruggeMe is now out @NatureGenetics! We explore hidden mechanisms of BRCA1 hereditary breast cancer using new mouse models, revealing unexpected tumor-like chromatin changes in Brca1-heterozygous normal mammary cells.
nature.com/articles/s41588-0…
Congrats to @cssmity and @NDBios @NDscience @NotreDame PhD student Hannah Gordon on this publication! Excited to see this out!
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
Schafer Lab retweeted
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
Schafer Lab retweeted
Please RT and help us get the word out. Scott Dixon @sjd956 and I are co-organizing the first @FASEBorg #Ferroptosis conference this summer! Awesome line up of speakers and room for additional short talks! Save the date & come join us July 27 - 31, 2025! 🤩events.faseb.org/event/11797…
ALT FASEB Ferroptosis Conference!
Schafer Lab retweeted
#NASmember Joan Brugge has advanced #breastcancer research in two major ways: through her studies of the processes in breast cancer's initiation and progression, and her explorations of how cellular receptors regulate the intracellular cytoskeleton. #BreastCancerAwarenessMonth
Schafer Lab retweeted
There is no such thing as a perfect leader.
In fact, if someone claims to be a perfect leader, they are probably not even a good leader, as they lack the self-awareness needed to seek out feedback and continue to grow and improve.
Congrats to Matt on this new role! His deep expertise and thoughtful demeanor was integral in working with many of us in @NDBios to launch a new introductory biology course sequence for @NotreDame students. @ieiatnd is in good hands!!
Congratulations to our founding director, Matt Kloser, on being named the new Hackett Family Director of Notre Dame's Institute for Educational Initiatives (IEI) 👏🏻
@ieiatnd
Read more: provost.nd.edu/news/institut…
Thanks to @bensahralab @clara_peek #notwitternav and @NorthwesternMed @LurieCancer for hosting the #MidwestMetabolism meeting yesterday. Had a great time attending with numerous members of the #SchaferLab @NDBios @NDscience @NotreDame.
@LyssiotisLab, next year at @UMich?
Schafer Lab retweeted
What an excellent meeting. Midwest has the best Metabolism 💪🏼
Thanks to @bensahralab, Nav, & Clara (@NorthwesternMed, @LurieCancer) for hosting. See ya next year in Ann Arbor!
@UMich represent 👇🏼〽️ #GoBlue
@YatrikShahLab, @DanWahlMD, @DNagrathLab
We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
Schafer Lab retweeted
We are excited to host the Midwest Metabolism Meeting (M3) this week! @LurieCancer @NUFeinbergMed. Join us to attend exciting talks and poster presentations by postdocs and students and a keynote address by Prof. Richard DiMarchi @IUBChemistry cancer.northwestern.edu/even…
Love to see @NDBios @NDScience @NotreDame friends/colleagues @alfmireles and @Felipe_hst on this list!
In honor of Hispanic Heritage Month, we present The Atlas of Inspiring Hispanic/Latinx Scientists. This resource showcases the scientific excellence of nearly 400 outstanding scientists. #LatinxAtlas #HispanicHeritageMonth
fredhutch.org/en/about/about…
Celebrated Father Bob’s inauguration as the 18th president of @NotreDame with colleagues/friends in @NDBios @NDScience. Excited for the future under his leadership!
Thoughtful piece by @FrezzaLab here---recommended reading for all in science in any career and at any career stage! Thanks for sharing your wisdom Christian.
When I meet other scientists, we more often discuss how to cope with failure rather than to achieve success. So I wrote this piece. I'd love to hear your views.
"Uno su mille ce la fa". Rethinking a scientist’s success network.febs.org/posts/uno-s… #FEBSnet
Schafer Lab retweeted
The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology.
Come be a colleague! More information here:
apply.interfolio.com/152596
Please share and retweet!
We recently said goodbye to @Schofield_isle Dr. Jamie Schofield as he moves on to a position with @JNJNews. Prior to his departure, Jamie was selected as the 2024 recipient of the Exemplary Graduate Research Career Award from @NDBios @NDscience . Congrats Jamie, good luck at J&J!
Schafer Lab retweeted
🥉 BRONZE
2021 biochemistry alum Yared Nuguse finished third in the men's 1500m, earning his first Olympic medal!
#ParisOlympics
Schafer Lab retweeted
Mark your calendars! The 1st FASEB #Ferroptosis conference, July 27-31 2025! We just posted our preliminary agenda! Spectacular line up and lots of space for short talks / late breaking speakers. Help us get the word out & come join us in 2025! @FASEBorg
events.faseb.org/event/11797…
Fellowship announcement! Congrats to @NDBios @NDScience @NotreDame #SchaferLab graduate student Lauren Young for receipt of a Research Supplement to Promote Diversity in Health-Related Research for our current @theNCI @NCICancerBio award. Congrats Lauren!
Also, thanks to my friend and colleague @alfmireles for helping us put together a strong application!