PhD student in the Stecher lab @LMU_Muenchen. Interested in bacterial evolution, inflammatory diseases, and all things microbiome.
Joined October 2022
- Tweets143
- Following227
- Followers90
- Likes568
Pinned Tweet
Nothing in biology makes sense except in the light of context!
Check out our new review on contextual factors shaping the mechanisms of intestinal colonization resistance.
@marta_tita15 (co-first)
@baerboletta
@cellhostmicrobe
Intestinal colonization resistance in the context of environmental, host & microbial determinants
@baerboletta & Co examine interplay between #microbes &their host that protects against infection & is influenced by metabolic, immune & environmental factors cell.com/cell-host-microbe/f…
Simon Woelfel retweeted
“To me it was a surprise to see how mums also acquired bacteria from other families through their kids” @mcarmen_collado said.
Read the full paper here: nature.com/articles/s41586-0…
Simon Woelfel retweeted
Microbial metabolite indole-3-propionic acid promotes mitochondrial respiration to suppress pro-inflammatory T cells, alleviating inflammatory bowel disease #IBD in humans and mice @h_sokol @NatMetabolism @Cyaner_Li
@Inserm 🇫🇷
nature.com/articles/s42255-0…
nature.com/articles/s42255-0…
Simon Woelfel retweeted
Our last paper on gut microbiota-derived cadaverine in intestinal inflammation is out in @cellhostmicrobe !
and it is FREE!
shorturl.at/q6y3w
Congratulations to @formigadc and thanks to all the contributors!
@MedecineSU @Inserm @crsa_paris @APHP @INRAE_IDF
#Thread 1/22
Simon Woelfel retweeted
Please retweet! We hire PIs working in microbiome+metabolism+cancer+allergies+autoimmunity+neurological+infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + top notch lab and equip. (e.g. SONY ID7000/10X Xenium/MACSima). Contact: stephan.rosshart@uk-erlangen.de
Simon Woelfel retweeted
New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @Aman_Kr25 @RobynTamblyn and the rest of the team.
nature.com/articles/s41586-0…
Simon Woelfel retweeted
Join us !
Open #Postdoc position in my lab (Paris, France), to work on the Role of the Gut #microbiota in Host Cells Energy Metabolism in Health and #IBD
see details here
🔽🔽🔽🔽
euraxess.ec.europa.eu/jobs/3…
please RT
Simon Woelfel retweeted
Please RT, our latest work just published @NatureComms „ONE MICROBIOTA TO RULE THEM ALL“ doi.org/10.1038/s41467-025-6… A big THANK YOU to the entire team of great scientists! #wildlings doi.org/10.1126/science.aaw4… @UniFAU @Hornegger #HTA
Simon Woelfel retweeted
Please RT! Looking for PIs working in microbiome, metabolism, cancer, allergies, autoimmunity, neurological and infectious diseases. We offer SPF-, gnotobiotic- and wildling-models + top notch equip., e.g. SONY ID7000, 10X Xenium, MACSima. Contact: stephan.rosshart@uk-erlangen.de
Simon Woelfel retweeted
The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.@FabiAlexFischer science.org/doi/10.1126/scia…
Simon Woelfel retweeted
Monosaccharides drive Salmonella gut colonization in a context-dependent or -independent manner | Nature Communications nature.com/articles/s41467-0…
Simon Woelfel retweeted
IBD-associated small molecules
@MoamenElmassry @donia_lab ID microbiome-encoded biosynthetic gene clusters that are enriched in Crohn’s disease patients & the small molecules they produce, which exacerbate disease when introduced to mouse models of colitis
cell.com/cell-host-microbe/f…
Simon Woelfel retweeted
Researchers at the Kennedy Institute @KIROxford have mapped the cellular dynamics of Inflammatory Bowel Disease and discovered why some patients benefit from anti-TNF treatment while others do not. youtube.com/watch?v=LDH73Uxz…
Simon Woelfel retweeted
We are looking for a postdoc in bioinformatics interested in broad questions about the ecology and evolution of host-associated microbiomes using social bees as model. Please share with potential candidates and if interested apply here: career5.successfactors.eu/ca…
Simon Woelfel retweeted
What a pleasure to see our bacterial-MERFISH work out in @ScienceMagazine this week! Congratulations to the talented team that led this effort--Ari, Yuanyou, and Nana! science.org/doi/abs/10.1126/….
Simon Woelfel retweeted
Please retweet. We are honored with the cover of Jan 2025 issue @TrendsImmuno dlvr.it/TGqWwm! We are all „Born to be Wild“! cell.com/trends/immunology/c… @CellPressNews #wildlings buff.ly/2ZqIqc5 scim.ag/4hX @UniFAU @Hornegger #HTA
Read the @TrendsImmuno Jan issue!! #Skinmacrophages, #EBV & #Bcell #metabolism, wild mice & natural #microbiota in research, biomolecular #condensates & #host #pathogen interactions, #Brainmacrophages in #vasculature, targeting ICI #toxicities, & more!! cell.com/trends/immunology/i…
Simon Woelfel retweeted
Yersiniabactin promotes profibrotic macrophages in Crohn’s
E. coli yersiniabactin sequesters zinc & stabilizes HIF-1α in macrophages, promoting profibrotic gene expression. HIF-1α+ Macs are abundant in fibrotic strictures of CD patients @ArthurTorchio
cell.com/cell-host-microbe/f…
Simon Woelfel retweeted
Glial-immune interactions in barrier organs are reviewed by @franzeprogatzky and colleagues:
mucosalimmunology.org/articl…
Simon Woelfel retweeted
The gut microbiome signature from different diets in >20,000 individuals. Red meat intake correlated with reduced cardiometabolic health; the opposite for plant-based foods or in omnivores with enriched plant-based intake
nature.com/articles/s41564-0… @NatureMicrobiol @nsegata @Fackelmeister
Simon Woelfel retweeted
Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
cell.com/cell-host-microbe/f…
@cellhostmicrobe @ArthurTorchio
Simon Woelfel retweeted
Please RT, because we are all „Born to be Wild“ and it really is time to think about reproducibility in biomedical research! A big THANK YOU to the brilliant Philipp Bruno and Thomas Schüler! @TrendsImmuno @CellPressNews #wildlings buff.ly/2ZqIqc5 @UniFAU @Hornegger #HTA
Born to be wild: utilizing natural microbiota for reliable biomedical research dlvr.it/TGqWwm #immunology