@SRosshart

Wildling lover at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany | Head of the Department of Microbiome Research, University Hospital Erlangen

mikrobiomik.uk-erlangen.de/en/
Joined August 2019
  • Tweets70
  • Following223
  • Followers335
3Media
Stephan P. Rosshart retweeted
Journal of Experimental Medicine@JExpMedOct 5
Gößwein, Ulmert, @SRosshart, and @jonatcoquet describe how colonizing laboratory mice with a naturally evolved #microbiota can restore important features of mammalian physiology & how this can benefit translational research. hubs.la/Q04z9l6c0 #FoundInTranslation
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Retweets appreciated! Natural microbiota-based mouse models - particularly Wildlings - improve reproducibility & translation across a remarkable range of biomedical fields. Our new @JExpMed Found in Translation! Thanks Isabel, Mario & @jonatcoquet! doi.org/10.1084/jem.20261517

Natural microbiota–based mouse models: A platform to fast-track translation of fundamental discov...

Conventional laboratory mice are invaluable tools in biomedical research, but their restricted microbial complexity limits their translational relevance. H

rupress.org
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For those who can’t get enough: nature.com/articles/s41467-0…

Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype

Nature Communications - Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably...

nature.com
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For the truly obsessed: science.org/doi/10.1126/scii…

Laboratory mice with a wild microbiota generate strong allergic immune responses

Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.

science.org
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Stephan P. Rosshart retweeted
Wilhelm Lab@LabWilhelm12 Dec 2025
Our new paper out in @ImmunityCP Congratulations to first author Chantal Wientjens! cell.com/immunity/fulltext/S…

Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic...

Immune cells must modulate their metabolism to adapt to tissue constraints. Wientjens et al. show that allergen-induced ILC2s and Th2 cells require cysteine-driven glutathione synthesis to prevent...

cell.com
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Very nice work just published in @ScienceAdvances Congratulations to Sagar, Katrin Kierdorf and the entire team! @KierdorfLab doi.org/10.1126/sciadv.aec91…

Distinct postnatal trajectories of mouse dendritic epidermal T cells and Langerhans cells indepen...

The mouse epidermis harbors two key resident immune populations—dendritic epidermal T cells (DETCs), a subset of invariant γδ T cells, and Langerhans cells (LCs), specialized tissue-resident macrop...

science.org
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RT appreciated! What if standard lab mice miss the real microbial game? Honored to be featured on the May cover @TrendsMicrobiol: “The microbial companion.” Our paper “Game of Microbes: A Wildling’s Guide” is out now: dlvr.it/TRl1Zs Thread below with more @CellPressNews
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For those who want to dive deeper: nature.com/articles/s41467-0…

Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype

Nature Communications - Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably...

nature.com
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For those who can‘t get enough: science.org/doi/10.1126/scii…

Laboratory mice with a wild microbiota generate strong allergic immune responses

Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.

science.org
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For those interested: Laboratory mice born to wild mice have natural microbiota and model human immune responses | Science
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For those who want more: Born to be wild: utilizing natural microbiota for reliable biomedical research: Trends in Immunology
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Stephan P. Rosshart retweeted
Trends in Microbiology@TrendsMicrobiolMar 27
Game of microbes: a wildling’s guide dlvr.it/TRl1Zs
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Please retweet! Ever wondered how to establish and maintain wildlings – and why they matter? Our new paper “Game of microbes: a wildling ’s guide” is now out in Trends in Microbiology dlvr.it/TRl1Zs - Thread below with key previous work @TrendsMicrobiol @CellPressNews

Game of microbes: a wildling’s guide

Laboratory mice housed under specific pathogen-free conditions are the standard model in biomedical research. However, frequent germ-free rederivation and barrier housing restrict microbial exposure...

cell.com
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For those truly interested: nature.com/articles/s41467-0…

Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype

Nature Communications - Here, the authors apply a standardized system, called TXsystem, to transplant wild mouse gut microbiota into SPF mice, developing “TXwildlings” mice that stably...

nature.com
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For those that cannot get enough: science.org/doi/10.1126/scii…

Laboratory mice with a wild microbiota generate strong allergic immune responses

Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.

science.org
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