@OnfeltLab

Multidisciplinary lab with special interests in immunology and microscopy.

 Stockholm, Sweden
onfeltlab.com
Joined August 2019
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  • Following272
  • Followers329
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Congratulations @QuirinHammer, @MalmbergLab, et al. I'm super happy that we could contribute to this work through Hanna Van Ooijen, now at @PixelgenTech, who did quantitative imaging of cell-cell interactions.
Quirin Hammer@QuirinHammer8 Jul 2024
Happy to share the final work from my post-doc with @MalmbergLab published in @CellStemCell today cell.com/cell-stem-cell/full… extensive 15-post-🧵 below
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I'm really happy that we could contribute to this great project by doing in situ imaging. Fantastic work by Taras and coworkers and @PatrickSandoz in my lab.
Taras Kreslavsky@TKreslavsky11 Jul 2024
Happy to see our story on tolerance to inflammation antigens @NatImmunol nature.com/articles/s41590-0… It grew from a naive question I had at my first immunology class: if some self molecules are only induced by pathogen how does immune system distinguish them from foreign antigens?1/n

Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces...

Nature Immunology - The thymus harbors a complex constitutively active inflammatory network with innate-like T cells representing one of its central nodes. Here, the authors show that these cells...

nature.com
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⚡️New preprint out! #Immunology #biophysics 1/ We show hidden functional immune cell states based on collective membrane properties, which are not directly visible via cell surface markers. biorxiv.org/content/10.1101/…

High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

Cell membranes undergo biophysical remodelling as an adaptation to the surroundings and to perform specific biological functions. However, the extent and relevance of such changes in human immune...

biorxiv.org
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This is a fantastic opportunity! Assistant Professorship specialised in in-vivo mimetic technology with a generous starting package. Come join us at Biophysics, Scilifelab, KTH, Sweden. kth.se/lediga-jobb/681359?l=…
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In several parallel projects now published in @ScienceMagazine, @slinnarsson's group at KI and colleagues @humancellatlas have created the most comprehensive atlases of human #brain cells to date, providing clues on different brain diseases. #neuroscience news.ki.se/cell-atlases-of-t…
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Induction of an hypoimmune state through unidirectional manipulation of the immune synapse. Work by outstanding @QuirinHammer and @KarloPerica in a fun collaboration with @Michel_Sadelain, @OnfeltLab and @FateThx. biorxiv.org/content/10.1101/…

Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells

Allogeneic cell therapies hold promise for broad clinical implementation, but face limitations due to potential rejection by the recipient immune system. Silencing of beta-2-microglobulin ( B2M )...

biorxiv.org
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De har granskat cellerna som dödar tumörer via.tt.se/pressmeddelande/33…

De har granskat cellerna som dödar tumörer | KTH

Forskare vid KTH och KI har studerat interaktionen mellan en speciell typ av immunceller och cancerceller. Med egenutvecklade metoder har de undersökt mekanismerna som är verksamma då tumörceller...

via.tt.se
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New paper from our group. Fantastic work by Patrick Sandoz (@PatrickSandoz), Kyra Kuhnigk and others in the lab. Also a big thanks to all collaborators and funding sources @MalmbergLab @ealici @KAWstiftelsen nature.com/articles/s41467-0…
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Dr. Quentin Verron practising for the Nobel prize at the KTH PhD diploma ceremony. Congratulations!
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ÖnfeltLab retweeted
KAW@KAWstiftelsen14 Oct 2022
23 #research projects receive SEK 700 million Human impact on wild animals, why women suffer more often from autoimmune diseases are examples of awarded project grants by Knut and Alice Wallenberg Foundation #KAW100 #science bit.ly/3CWEfuB
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👇👇Our new method to measure molecular interactions directly in cells with rotational diffusivity and #photoswitching is out! Congrats @andreavolpato_ @dirk_ollech @DamentiMartina and our awesome collaborators @AndrewGYork @Maria_Ingaramo and BarbaraMüller
Nature Biotechnology
@NatureBiotech10 Oct 2022
Extending fluorescence anisotropy to large complexes using reversibly switchable proteins go.nature.com/3MoM931
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ÖnfeltLab retweeted
Neo Shi Yong@DrNeosy21 May 2022
proud to see that my first student’s thesis work published after 3 years🙏🏼🍾
Journal for ImmunoTherapy of Cancer
@jitcancer17 May 2022
New #JITC article: A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models bit.ly/3FQGW0R @hugogdtc @bentoaz
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strategiska.se/en/ssf-suppor…
Immune cell working against the flow to send a timely message (wait for it). Happy Valentines! Cells provided from generous blood donor 🙏 and imaging done by ⁦@ZambardaChiara⁩
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Congratulations to @Vale_Carannante for nailing her impressive thesis on NK cells in the tumor microenvironment. We look forward to the defense in a few weeks with @CerwenkaLab as opponent. @karolinskainst
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Open post-doc position in the Oslo node of Malmberg Lab. Join us in our effort to develop allo NK cell therapy with increased persistence. We look forward to welcome you in the team! 2411.webcruiter.no/Main2/Rec…
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Very happy that we could be a part of this study. Congratulations Karoliina and Dan!
Dan Davis@dandavis10118 Jan 2022
Here's our new paper, led by brilliant PhD student Karoliina Tuomela, about NK cells and cancer therapy (in PNAS) #nkcell #immune #cancer pnas.org/content/119/3/e2111…

Radiotherapy transiently reduces the sensitivity of cancer cells to lymphocyte cytotoxicity | PNAS

The impact of radiotherapy on the interaction between immune cells and cancer cells is important not least because radiotherapy can be used alongsi...

pnas.org
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If you are interested to work in my lab and contribute to human studies on cell-mediated immunity to viral infections, you should apply to this position as a Research Assistant. ki.varbi.com/en/what:job/job…
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Painted by multitalanted @ZambardaChiara who is also a great scientist knowing a thing or two about adcc, adcp and microchip screening!
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Only 5 days left to apply for a postdoc position in my group. Join us and get to do top research on NK cells in lung cancer in a great research environment! ki.varbi.com/en/what:job/job…

Postdoctoral studies in human NK cell biology (scholarship)

Do you want to contribute to top quality medical research? We are looking for a highly motivated and skilled postdoctoral researcher to join the Michaëlsson group in our efforts to decipher the role

ki.varbi.com
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