@OnfeltLab

Multidisciplinary lab with special interests in immunology and microscopy.

 Stockholm, Sweden
onfeltlab.com
Joined August 2019
  • Tweets107
  • Following272
  • Followers329
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⚡️New preprint out! #Immunology #biophysics 1/ We show hidden functional immune cell states based on collective membrane properties, which are not directly visible via cell surface markers. biorxiv.org/content/10.1101/…

High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

Cell membranes undergo biophysical remodelling as an adaptation to the surroundings and to perform specific biological functions. However, the extent and relevance of such changes in human immune...

biorxiv.org
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In several parallel projects now published in @ScienceMagazine, @slinnarsson's group at KI and colleagues @humancellatlas have created the most comprehensive atlases of human #brain cells to date, providing clues on different brain diseases. #neuroscience news.ki.se/cell-atlases-of-t…
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Induction of an hypoimmune state through unidirectional manipulation of the immune synapse. Work by outstanding @QuirinHammer and @KarloPerica in a fun collaboration with @Michel_Sadelain, @OnfeltLab and @FateThx. biorxiv.org/content/10.1101/…

Genetic ablation of adhesion ligands averts rejection of allogeneic immune cells

Allogeneic cell therapies hold promise for broad clinical implementation, but face limitations due to potential rejection by the recipient immune system. Silencing of beta-2-microglobulin ( B2M )...

biorxiv.org
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ÖnfeltLab retweeted
KAW@KAWstiftelsen14 Oct 2022
23 #research projects receive SEK 700 million Human impact on wild animals, why women suffer more often from autoimmune diseases are examples of awarded project grants by Knut and Alice Wallenberg Foundation #KAW100 #science bit.ly/3CWEfuB
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👇👇Our new method to measure molecular interactions directly in cells with rotational diffusivity and #photoswitching is out! Congrats @andreavolpato_ @dirk_ollech @DamentiMartina and our awesome collaborators @AndrewGYork @Maria_Ingaramo and BarbaraMüller
Nature Biotechnology
@NatureBiotech10 Oct 2022
Extending fluorescence anisotropy to large complexes using reversibly switchable proteins go.nature.com/3MoM931
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ÖnfeltLab retweeted
Neo Shi Yong@DrNeosy21 May 2022
proud to see that my first student’s thesis work published after 3 years🙏🏼🍾
Journal for ImmunoTherapy of Cancer
@jitcancer17 May 2022
New #JITC article: A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models bit.ly/3FQGW0R @hugogdtc @bentoaz
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Open post-doc position in the Oslo node of Malmberg Lab. Join us in our effort to develop allo NK cell therapy with increased persistence. We look forward to welcome you in the team! 2411.webcruiter.no/Main2/Rec…
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If you are interested to work in my lab and contribute to human studies on cell-mediated immunity to viral infections, you should apply to this position as a Research Assistant. ki.varbi.com/en/what:job/job…
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Only 5 days left to apply for a postdoc position in my group. Join us and get to do top research on NK cells in lung cancer in a great research environment! ki.varbi.com/en/what:job/job…

Postdoctoral studies in human NK cell biology (scholarship)

Do you want to contribute to top quality medical research? We are looking for a highly motivated and skilled postdoctoral researcher to join the Michaëlsson group in our efforts to decipher the role

ki.varbi.com
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ÖnfeltLab retweeted
Dan Davis@dandavis1016 Dec 2021
My ‘big idea’ article in The Guardian - means a lot to me, please RT theguardian.com/books/2021/d…

The big idea: how much do we really want to know about our genes?

Genetic data will soon be accessible like never before. The implications for our health are huge

theguardian.com
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Interested in exploring the role of tissue-resident NK cells in lung cancer and finding ways to harness their function? Looking for a post-doc position in a great research environment? Look no further – apply to join our group at Karolinska Institutet! ki.varbi.com/en/what:job/job…

Postdoctoral studies in human NK cell biology (scholarship)

Do you want to contribute to top quality medical research? We are looking for a highly motivated and skilled postdoctoral researcher to join the Michaëlsson group in our efforts to decipher the role

ki.varbi.com
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Replying to @OnfeltLab
@OnfeltLab present data on @affimed innate cell engagers (ICE®) at the 36th Annual Meeting of SITC @sitcancer showing ICE® induced enhanced NK cell cytotoxicity and increased numbers of serial killers. #Innateimmunity $AFMD #NKcells #Immunotherapy
Affimed@affimed12 Nov 2021
We’re excited to be presenting data on our innate cell engagers at this year’s @sitcancer conference. Learn more here: bit.ly/3kviDvZ
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Want to take part in forming a world-leading research community of data-driven life scientists? We are recruiting 20 DDLS Fellows (tenure track principles, with a budget of 17 MSEK). More about the program, funded by @KAWstiftelsen: bit.ly/2SmN4tp bit.ly/3vZRXXb
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the Cell and Gene Therapy group at Karolinska Institutet Sweden, is looking for a Postdoctoral researcher in Induced Pluripotent Stem Cells (iPSCs) to join the group and NextGenNK! ki.varbi.com/se/what:job/job…
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the Cell and Gene Therapy group at Karolinska Institutet Sweden, is looking for a new PhD student to join the group and NextGenNK! kidoktorand.varbi.com/se/wha…

Doctoral (PhD) student position in Immunology and Gene Therapy

Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individu

kidoktorand.varbi.com
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[Please RT] Now open for applications: DDLS Fellows positions! Tenure track & budget of 17 MSEK (salary for 5 years for the DDLS Fellow, two PhDs, two postdocs & running costs).4 research areas (see image). All 20 positions published over the coming weeks: bit.ly/3q164dc
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Many data driven life science positions in Swedish universities. Generous start-up fund (ca. 1.5M Euro) and many networking opportunities.. Check here: su.se/english/about-the-univ… kth.se/en/om/work-at-kth/led… scilifelab.se/careers?filter…
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Job opportunity: Help us develop drugs for brain cancer! We’re looking for an experienced staff scientist to develop and run advanced animal models of human brain cancer. Please RT. nature.com/naturecareers/job…
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A study of natural killer cells in @SciSignal illustrates how ligand patterns affect these cells’ ability to neutralize targets of the immune system—and hints at how target cells such as tumor cells may be able to escape destruction. fcld.ly/0qmei3f #Immunology
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Using artificial immune synapses, @bonfelt and co show that the spatial distribution of activating proteins affects how well #NaturalKiller cells can form immune synapses with target cells and release granules. @KTHuniversity #Immunology fcld.ly/9bncm8d
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