@OfialLab

Developing nucleophilicity and electrophilicity scales at LMU München. We make colours disappear! PI run page. (inactive)

 LMU München
ofial.cup.uni-muenchen.de/
Joined June 2021
  • Tweets66
  • Following113
  • Followers317
6Media
Defining the Synthetic Scope of ortho-Quinone Methides by Quantifying their Electrophilicity (Armin R. Ofial @OfialLab and co-workers) #openaccess 🔓 onlinelibrary.wiley.com/doi/…

Defining the Synthetic Scope of ortho‐Quinone Methides by Quantifying their Electrophilicity

The electrophilicities E of ortho-quinone methides (oQMs) were determined by following the kinetics of oQM reactions with carbanions in DMSO. Embedding the oQMs in Mayr's reactivity scales facilita...

chemistry-europe.onlinelibrary.wiley.com
3
1
9
1,875
It was a real pleasure to give a lecture at the "Organisch-Chemischen Kolloquium" today at LMU Munich University @LMU_Muenchen. Thanks @SaitoGroup for the invitation and wonderful discussions with @OfialLab and all researchers from the chemistry department.
2
34
2,368
#EurJOC 2-Methylene-1,2-dihydropyridines (2-pyNHOs): Highly Nucleophilic Enamines by @MMHansmann_chem, @Ofial_Lab, and co-workers #OpenAccess onlinelibrary.wiley.com/doi/…

2‐Methylene‐1,2‐dihydropyridines (2‐pyNHOs): Highly Nucleophilic Enamines

2-Methylene-1,2-dihydropyridines (2-pyNHOs) are enamines with strongly polarized exocyclic π-bond. The 2-pyNHOs react with quinone methides to give zwitterionic adducts or the entirely neutral...

chemistry-europe.onlinelibrary.wiley.com
2
6
753
Ofial_Lab retweeted
EurJOC@EurJOC19 Mar 2024
Reactivity of Electrophilic Trifluoromethylating Reagents by Armin R. Ofial, Herbert MayrH, and co-workers (@OfialLab, @Mayrs_Scale, @LMU_Muenchen) onlinelibrary.wiley.com/doi/…
1
6
1
33
2,945
Finish of the year: A new class of mesoionic NHOs just accepted @angew_chem. Big thanks to the group as well as the joint work with @OfialLab and @RJ_Mayer. Happy New Year! onlinelibrary.wiley.com/doi/…
3
12
1
121
7,273
Nucleophilicity of 4-(Alkylthio)-3-imidazoline Derived Enamines (Ofial, Trapp, et al.) @TrappLab, @OfialLab onlinelibrary.wiley.com/doi/…

Nucleophilicity of 4‐(Alkylthio)‐3‐imidazoline Derived Enamines

Enamine activation is a key method to enhance the reactivity of carbonyl compounds in α-alkylation reactions. In spite of their possible role in prebiotic chemistry, enamines derived from aldehydes...

chemistry-europe.onlinelibrary.wiley.com
4
16
3,969
Check out our reactivity database! It is a compilation of electrophilicity and nucleophilicity parameters for a wide range of compounds. cup.lmu.de/oc/mayr/reaktions…
2
1
11
After a full day of physical organic chemistry at #ESOR2023 symposium in Amsterdam, time for diner with @RJ_Mayer, @OfialLab, @ME_Moret and @BreugstLab. #ESOR2023. Great to meet previous colleagues and new one!
7
42
2,772
Armin R. Ofial (@OfialLab) of @LMU_Muenchen presents a contributed talk @ESOR2023 on the upper limit of nucleophilicity scales: mesoionic N-heterocyclic olefins. #ESOR2023
8
25
1,743
Ofial_Lab retweeted
EurJIC@EurJIC13 Sep 2023
We invite you to join our Virtual Symposium on October 11, moderated by @GrebGroup, in which four experts will present and discuss exciting aspects of modern Lewis-acid Chemistry. Do not miss this opportunity, registration is open! 👇 attendee.gotowebinar.com/reg…
31
2
69
22,036
Our joint work with @OfialLab is just accepted @angew_chem. Big thanks to the team for their great effort! onlinelibrary.wiley.com/doi/…
3
9
92
9,010
Can Mayr’s reactivity scales be applied to rationalize the mechanism of 3+2 cycloadditions? Absolutely! Check out Le‘s massive kinetic work in @J_A_C_S to which I contributed the computational analysis. @OfialLab doi.org/10.1021/jacs.2c13872
9
1
41
9,151
Ofial_Lab retweeted
EurJOC@EurJOC20 Mar 2023
📢Together with our Board Member @samilakhdar1, we are proud to present the upcoming talk by Prof. Scott Denmark as part of the Physical Organic Chemistry webinar series! Save the date and join us this Thursday at 4 pm CET 👉bit.ly/3JF1L2S
1
27
3
78
21,280
Ofial_Lab retweeted
EurJOC@EurJOC14 Feb 2023
Nucleophilicities of Cyclic alpha-Diazo Carbonyl Compounds by Armin R. Ofial and co-workers (@OfialLab @LMU_Muenchen) #OpenAccess onlinelibrary.wiley.com/doi/…
4
25
3,122
Cyclic ɑ-diazo carbonyl compounds have been added to the database doi.org/10.1002/ejoc.2023000…

Nucleophilicities of Cyclic α‐Diazo Carbonyl Compounds

The kinetics of the reactions of cyclic α-diazo carbonyl compounds with electrophilic benzhydrylium ions were evaluated to determine the Mayr reactivity descriptors N (and sN) of the nucleophiles....

chemistry-europe.onlinelibrary.wiley.com
1
14
1,397
The 1st part of the special issue in SYNTHESIS (@thiemechemistry), in honor of Prof Alain Krief @Unamur just arrived in my office. Starting 2023 with great reviews, minireviews and articles. thieme-connect.com/products/…. Thanks @MarkLautens, @SBaumannThieme, @Silicon_Martin. 1/2
2
6
1
42
7,489
Today a Belgian icon of chemistry is turning 80🍾🎂. On the behalf of the @UNamur chemistry department and of hundreds of authors and participants to the SYNTHESIS special issue (@Thiemechemistry : thieme-connect.com/products/… ) and to the forthcoming symposium, we wish...▶️▶️
1
10
2
49
It was great today to have Dr. Armin Ofial (@OfialLab) from @LMU_Muenchen for the last organic chemistry lecture of the year in our department/institute @UNamur: "Reactivity Scales as Tools for Analyzing Polar Organic Reactions: Dos and Don'ts".
2
13
Catalysts or initiators? In triarylborane-initiated conjugated Mukaiyama or Hosomi-Sakurai additions, a rather complex reaction network emerges due to competing Lewis acid catalysts. Check out my paper in @ACSCatalysis with @OfialLab! (1/5) pubs.acs.org/doi/pdf/10.1021…
1
8
1
36
Interested to join our group (@UNamur, Belgium)? Postdoctoral position (one year) in physical organic chemistry starting in March 2023. 🗓️Apply before January 2023🗓️ 🙏 RT much appreciated⬇️ euraxess.ec.europa.eu/jobs/8…
5
43
1
86
Load more