@Mayrs_Scale

Providing regular updates for Mayr's Database of Reactivity. Take a look at: https://xitter.cf/t.co/2lW4aq4nPf

 LMU München
cup.lmu.de/oc/mayr/reaktionsdatenbank2/
Joined July 2021
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Check out our reactivity database! It is a compilation of electrophilicity and nucleophilicity parameters for a wide range of compounds. cup.lmu.de/oc/mayr/reaktions…
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Sesamol-derived ortho-quinone methides (o-QM) have been added.
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Lactone enolates of isochroman-3-ones and 2-coumaranones have been added. doi.org/10.1021/acs.joc.4c00…
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Mesoionic pyridinium-derived N-heterocyclic olefins (py-mNHOs) have been added. onlinelibrary.wiley.com/doi/…

Pyridinium‐Derived Mesoionic N‐Heterocyclic Olefins (py‐mNHOs)

A new class of mesoionic, six-membered N-heterocyclic olefins derived from 3-methylpyridinium ions (py-mNHOs) is reported. Py-mNHOs are among the most reactive neutral nucleophiles on the Mayr...

onlinelibrary.wiley.com
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Check out the 2023 updates: Enamines derived from 4-(alkylthio)-3-imidazolines and aldehydes have been added doi.org/10.1002/chem.2023027…

Nucleophilicity of 4‐(Alkylthio)‐3‐imidazoline Derived Enamines

Enamine activation is a key method to enhance the reactivity of carbonyl compounds in α-alkylation reactions. In spite of their possible role in prebiotic chemistry, enamines derived from aldehydes...

chemistry-europe.onlinelibrary.wiley.com
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Check out the 2023 updates: Mesoionic N-heterocyclic olefins (mNHOs) have been added doi.org/10.1002/anie.2023097…

Pushing the Upper Limit of Nucleophilicity Scales by Mesoionic N‐Heterocyclic Olefins

A series of mesoionic N-heterocyclic olefins (mNHOs) was synthesized and their reactions with Michael acceptors and CO2 investigated. The outstandingly high nucleophilicities of mNHOs were determin...

onlinelibrary.wiley.com
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Cyclic ɑ-diazo carbonyl compounds have been added to the database doi.org/10.1002/ejoc.2023000…

Nucleophilicities of Cyclic α‐Diazo Carbonyl Compounds

The kinetics of the reactions of cyclic α-diazo carbonyl compounds with electrophilic benzhydrylium ions were evaluated to determine the Mayr reactivity descriptors N (and sN) of the nucleophiles....

chemistry-europe.onlinelibrary.wiley.com
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NADH and NADPH reactivities (in water, pH 7) determined by @RJ_Mayer and Moran (@MoranLabUdS) have been added pubs.rsc.org/en/content/arti…

Quantification of the hydride donor abilities of NADH, NADPH, and BH3CN− in water†

The nucleophilic reactivities of the hydride donors NADH, NADPH, and BH3CN− in water were quantified using kinetic measurements with benzhydrylium ions as

pubs.rsc.org
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Alkenyl boronate nucleophilicity by @pengliu_group, Ready and co-workers has been added to the database. pubs.acs.org/doi/10.1021/jac…

Mechanistic Basis for the Iridium-Catalyzed Enantioselective Allylation of Alkenyl Boronates

Abstract. Iridium­(phosphoramidite) complexes catalyze an enantio- and diastereoselective three-component coupling reaction of alkenyl boronic esters, orga

pubs.acs.org
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The electrophilicities of diazo compounds in azo couplings have been added to the reactivity database. doi.org/10.1002/chem.2022013…

Quantification of the Electrophilicities of Diazoalkanes: Kinetics and Mechanism of Azo Couplings...

Enamines and sulfonium ylides attack the terminal nitrogen of diazoalkanes with rate-determining formation of zwitterions. The measured second-order rate constants were used to determine the one-bo...

chemistry-europe.onlinelibrary.wiley.com
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The reactivity database has been updated to include the nucleophilicity parameter of diazocyclopentadiene (Synthesis 2021, DOI: 10.1055/s-0041-1737327)
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Electrophilic indoles from @samilakhdar1 and Isabelle Chataigner have been added to the database. (ChemCommun 2021, doi: 10.1039/d1cc04074j) pubs.rsc.org/en/content/arti…
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MayrsReactivityScale retweeted
Ofial_Lab@OfialLab25 Jun 2021
Check out our reactivity scales poster! A convenient way to compare the nucleophilicities and electrophilicities of various compounds. cup.lmu.de/oc/mayr/2020_Mayr…
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