B-cell dynamics, oncogenic signaling in B-cell malignancies @YaleUniversity. Since January 2026 @muschenlab.bsky.social
New Haven, CT
Joined January 2021
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Müschen Lab retweeted
A signaling loop centering on the protein CD25 sustains the growth of acute leukemias such as #AML and #B-ALL by fine-tuning the activity of oncogenic tyrosine kinases, according to a new study. @MuschenLab @Yale scim.ag/4rMXddQ
Müschen Lab retweeted
New research presented at #ASH24 from the @MuschenLab by @RuifengSun2 shows the previously unrecognized role of PKCδ and CD25 in to control BCR signaling in Mature B-Cell #Lymphoma. @YaleMed @OncoAlert @YaleHematology
ash.confex.com/ash/2024/webp…
Müschen Lab retweeted
.@RuifengSun2 presents research @MuschenLab showing CD25 as a regulator of the B pathway and suggesting it as a new therapeutic target for acute lymphoblastic leukemia #ALL at #ASH24. @YaleHematology @OncoAlert @YaleMed @YaleIBIO ash.confex.com/ash/2024/webp…
Müschen Lab retweeted
Zhangliang Cheng @MuschenLab presents on the 3 stages of B Cells and oscillations between MYC and BCL6 dependent states in B Cell #lymphoma. #ASH24 @YaleMed @SmilowCancer
Müschen Lab retweeted
Leo Meriranta @Merijellona is defending his PhD thesis “molecular cross-section of high/risk #DLBCL” today. It is an honor to chair and enjoyable to listen high level scientific discussion lead by Dr Dan Hodson. Thank you Dan, well done Leo!
Müschen Lab retweeted
The ‘China Initiative’ failed US research and national security. Don’t bring it back. thehill.com/opinion/national…
Müschen Lab retweeted
Excited our final version of @tineisadora's work on targeted protein relocalization is out today @nature! Molecular control over protein localization could offer new opportunities for therapeutics and biological discovery. @Stanford_ChEMH @StanfordUChem nature.com/articles/s41586-0…
Müschen Lab retweeted
Very happy and proud to see this study on PU.1 transcription factor "redistribution" and its mechanistic implications out in @NatureGenet today. Huge congrats to lead author @SamuelJohnTayl1! (recruiters watch out: Sam is on the faculty job market now...!). A big thank you also to the entire collaborative team including the twitterless Gregory Poon and Kristy Stengel! @EinsteinCellBio @Einstein_SCI @EinsteinMed
Super thrilled to share our article on pharmacological PU.1 repositioning published in Nature Genetics today! Massive thanks to everyone involved!
Article -> nature.com/articles/s41588-0…
A digestible PUree of the main findings (aka Research Brief) -> nature.com/articles/s41588-0…
Müschen Lab retweeted
Immunologists out there, join us in New York City and @nyugrossman !! All candidates will be considered but the ones with a track record in the development of cutting-edge experimental, engineering and computational approaches to analyze immune responses are particularly encouraged to apply. Apply at: apply.interfolio.com/155023 !! @NYUGSOM_Path #Immunology
Müschen Lab retweeted
Thoroughly enjoyed my visit to @CellSignal and discovering our many shared priorities. Plus, nothing says “Northeastern Massachusetts” like lush tropical gardens, with Italian espresso machines planted throughout the atrium.
Müschen Lab retweeted
In the Spotlight: Tuning Responses to Polatuzumab Vedotin in B-cell Lymphoma, by Etienne Leveille and colleagues. @MuschenLab @Yale bit.ly/3XPEwKo
Müschen Lab retweeted
1/ Exactly one year after my PhD defense, I am very excited to share with you the last chapter of my thesis published today in @Nature about humans with inherited TNF deficiency: nature.com/articles/s41586-0….
Müschen Lab retweeted
Thrilled to share our latest work in Science. We discovered a novel non-mobilizable HSC pool. I really appreciate the huge support from @SteidlUli @The_Will_Lab and all the co-authors. I hope Paul is smiling at all of us from above! science.org/doi/10.1126/scie…
Müschen Lab retweeted
Hi! Recently became independent. Working on epigenetic dysregulations in B cell lymphoma and their impact on the tumor micro environment. #NewPI
Müschen Lab retweeted
We study epigenetics in cancer immunology at #Yale and we are hiring: miceviclab.github.io/postdoc… #newPI
Müschen Lab retweeted
Science needs excellent editors. And scientists need to stand by these editors who are fighting for a decent compensation and a respectable way of life.
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Müschen Lab retweeted
wonderful - keep up the good work!
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Müschen Lab retweeted
The 2 lymphomas (DLBCL / TCL) were immunophenotypically & morphologically distinct, but both shared EBV infection by EBER ISH. 6/15
Müschen Lab retweeted
On behalf of the organisers: @Borkhardt_Lab @heinaniemi & myself, a huge thank you to all speakers, participants and volunteers that made the @EMBO workshop on childhood blood cancer such a success! And for sharing fantastic science, ideas & more. #OneTeam #EMBOchildhoodCancer
