The Malmberg Lab studies the functional regulation of natural killer (NK) cells and seeks to employ new insights in NK cell biology in cancer immunotherapy
Oslo, Norway
Joined January 2016
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MalmbergLab retweeted
Online Now: Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor dlvr.it/TFV5VC
MalmbergLab retweeted
We have an open 2-year postdoc position focusing on computational approaches to identify antigen-specific immune receptors from adaptive immune repertoire data. Application deadline: Nov 6. jobbnorge.no/en/available-jo…
MalmbergLab retweeted
Working with a great team including @NathanSinghLab & Stephan Mielke to organize @KeystoneSymp Immune #CellTherapy: Advances in #Cancer and #AutoimmuneDisease
Please join us to explore emerging research in Banff, March 16-19, 2025 | Fairmont Banff Springs, Banff, AB, Canada
Scholarship Deadline: December 9, 2024
Short Talk Abstract Deadline: December 9, 2024
Poster Abstract Deadline: February 20, 2025
Early Registration Deadline: January 28
2025keysym.us/KSCellTherapy2… #KSCellTherapy25 pic.x.com/wb3hgSFKGz
keystonesymposia.org/confere…
MalmbergLab retweeted
GPR56 functions as an upstream checkpoint for migration of highly differentiated NK cells @J_Immunol @MalmbergLab @DanielPal88
doi.org/10.4049/jimmunol.240…
MalmbergLab retweeted
Exciting work by @AmirHorowitz and team! Congrats to all.
HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer
biorxiv.org/content/10.1101/…
MalmbergLab retweeted
Understanding NK cell heterogeneity dlvr.it/T9WTGk
MalmbergLab retweeted
Malmberg and colleagues provide a single-cell transcriptional reference map of healthy human NK cells and use this profile of tumor infiltrating NK cells. Read it here: rdcu.be/dM6V4
nature.com/articles/s41590-0…
MalmbergLab retweeted
Taken together, in this study in @CellStemCell, we demonstrate that modulating the immune synapse can be a promising strategy to avert rejection by the host and hopefully further unlock 🔓 the potential of next-generation allogeneic #Immunotherapy against #cancer
MalmbergLab retweeted
Huge congratulations @MalmbergLab and co-authors on this groundbreaking paper! A significant advance for the field #NK #CancerResearch #immunotherapy
Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." nature.com/articles/s41590-0…. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED
MalmbergLab retweeted
A landmark paper for the NK cell field, great work, congratulations team!
Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." nature.com/articles/s41590-0…. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED
MalmbergLab retweeted
@CoE_PRIMA breakfast meeting @OsloSciencePark - From complex biology to development of biomedical technologies! @UniOslo_MED @Oslounivsykehus @forskningsradet
MalmbergLab retweeted
Our perspective with @fabian_theis , @YUHANHAO2 , and @mo_lotfollahi on the power and potential of reference mapping across disease states, molecular modalities, perturbations, and species: cell.com/cell/fulltext/S0092…
MalmbergLab retweeted
Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/S0092…
MalmbergLab retweeted
Full version of the article here: 👇
doi.org/10.1182/bloodadvance…
MalmbergLab retweeted
Prof @ebba_sohlberg NK cell expert @karolinskainst GREAT TALK! Educates on adaptive NK cells/restricted by a single KIR/returns to “missing self” hypothesis/HLA-C mismatch unleashes killing/Developed GMP alloreactive ADAPT-NK #TIMO2024 @sitcancer HLA-E checkpoint conversion
MalmbergLab retweeted
In this article, we provide a brief perspective of the promise of allogeneic cell therapies against cancer. We consider rejection by the recipient as a central pitfall and discuss approaches to reduce this rejection by genetic engineering
nature.com/articles/s41577-0…
MalmbergLab retweeted
…and last but not least you can find some data on the topic here: biorxiv.org/content/10.1101/…
(Hopefully in final form available soon 🤓)
MalmbergLab retweeted
Rejection is a key challenge limiting the translation of allogeneic cell therapies. In our new @NatRevImmunol Perspective, @QuirinHammer, @KarloPerica, Michel Sadelain, @MalmbergLab, and I discuss strategies to engineer allorejection-resistant cells. rdcu.be/dFBAM
MalmbergLab retweeted
New opening for a PhD student in my lab, co-supervised with @F_Lund_Johansen . This position is ERC-funded and focuses on novel experimental technologies for antibody-antigen binding screening 📷 jobbnorge.no/en/available-jo…