Head of Data Science at Neptune Bio

Joined May 2019
In April 2022, on a quiet afternoon, Rahul invited Harm and me to cofound a startup, Neptune Bio. Three years have passed. From pitching to investors, building a network with other founders, setting up a company, to publishing my first senior-author paper!
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Now, I am excited to begin my postdoctoral position in Eddie Chang’s lab at UCSF, where I will focus on decoding human neuronal activity underlying language articulation and perception. Still working at the single-cell level, but this time studying neuronal firing patterns.
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I do appreciate Eddie’s courage to recruit someone from outside the field. I hope to bring the same energy and excitement to solve some important and fundamental questions in this new and cool area!
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Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
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A big step in virtual cell!
We release 300 million single cells (and counting) for virtual cell modeling, our first AI agent work @arcinstitute, and 100 million perturbed cells with @vevo_ai This is the largest repository available, open source, and hopefully an ImageNet for cell biology
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YUHAN HAO retweeted
We release 300 million single cells (and counting) for virtual cell modeling, our first AI agent work @arcinstitute, and 100 million perturbed cells with @vevo_ai This is the largest repository available, open source, and hopefully an ImageNet for cell biology
Today, we're launching the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements. As the initial contributions, @vevo_ai has open sourced Tahoe-100M, the world's largest single-cell dataset, mapping 60,000 drug-cell interactions, and we’re announcing scBaseCamp, the first RNA sequencing data repository curated using AI agents. Combined, the release includes data from over 300 million cells. arcinstitute.org/news/news/a…
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YUHAN HAO retweeted
We trained a genomic language model on all observed evolution, which we are calling Evo 2. The model achieves an unprecedented breadth in capabilities, enabling prediction and design tasks from molecular to genome scale and across all three domains of life.
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It's an exciting experience to engage in discussions and exchange ideas about computational challenges and opportunities in the single-cell area with these remarkable individuals, @mo_lotfollahi @fabian_theis @satijalab ! Ultimately, this becomes our current perspective in Cell.
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Our article reinterprets reference mapping, moving from short reads to single-cell analysis, and focuses on two key points: building and using single-cell references.
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Deeply sad to learn the news of James Simons' passing, a legendary mathematician and quantitative investor who successfully decoded market patterns. By coincidence, I completed my PhD research at NYGC, an institute he generously supported.
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On May 9 last year, I was incredibly fortunate to speak with him, during the time we even discussed combinatorial generalization. Our conversation ended with his commonly used but best words, "Good Luck." Thank you, James. R.I.P.
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Happy #singlecellgenomicsday 2024 with so many incredible presentations! This is my first time joining the SCGD outside the Satija lab, but I'm still surrounded by a group of exceptional people. We all gathered to enjoy the sessions at the Alexandria Center, NYC!
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Want to hear about the latest updates/new techniques in single cell and spatial genomics? Check out the full agenda for our Single Cell Genomics Day on Friday, 3/29. All talks will be live-streamed (no registration required) at satijalab.org/scgd
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YUHAN HAO retweeted
In some new work (the first from the new lab!), we lay out a vision for a biological foundation model that unites DNA, RNA, and protein modalities and operates at molecular, systems, and genome levels of scale. Blog: arcinstitute.org/news/blog/e… Preprint: arcinstitute.org/manuscripts…
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This is the recording of a public talk I gave in the Copenhagen Koncerthuset. It was an amazing experience to talk to a sold out concert hall before an audience of >1000 or so. Thanks to Jacome Armas for making this possible. youtube.com/watch?v=6FZ12DuO…
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I'm honored to be invited to present a talk at MIA Broad. It was a lot of fun discussing research with junior and senior colleagues at Broad. If you're curious about the algorithm details in Seurat v5, here is the talk: youtube.com/watch?v=ao9XdyZ4…
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Simultaneously, I'm excited to announce my new career path as the Head of Data Science at Neptune Bio. If you are interested in single cell + combinatorial perturbation + deep learning, please join us.
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We're actively recruiting for both wet-lab and computational roles at various levels. If you or someone you know is interested, please reach out to me. Your help in spreading the word is greatly appreciated! boards.greenhouse.io/neptune…
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