@LabPombo

Genome, genes, regulation @BIMSB_MDC

 Berlin
mdc-berlin.de/pombo
Joined February 2019
  • Tweets82
  • Following584
  • Followers1.4K
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Extensive folding variability between homologous chromosomes in mammalian cells biorxiv.org/cgi/content/shor… #bioRxiv
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Ibai Irastorza@batxes12 May 2024
I am very pleased to share that our latest research🧑‍🔬 from @LabPombo, about allele-specific chromatin structure 🧬, now live on bioRxiv. Shout out to @apombo1, Alexander Kukalev, Rieke Kempfer and the rest of the team for this remarkable work of science. ↓ Short thread below ↓
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What are the functional roles of 3D genome organization? Our paper in @Nature led by @_prashantbhat demonstrates how dynamic 3D genome organization around nuclear speckles plays a crucial role in regulating mRNA splicing efficiency. rdcu.be/dHkez
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Incredibly excited that the DFG is establishing a priority programme in #neuroepigenetics. Initiative lead by Tanja Vogel with support from @BenschZimmer, André Fischer, @apombo1 and myself. Looking forward to great science to emerge from #EPIADAPT! dfg.de/de/service/presse/pre…
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Thanks for the warm welcome these past weeks @QMULepigenetics! What an amazing community to be a part of 🤩🧬👨‍🔬👩‍💻
@qmulepigenetics@QMULepigenetics7 Mar 2024
We are excited to welcome Elena Torlai Triglia @ele_tt qmulepigenetics.com/torlaitr… to @QMULepigenetics. Elena will bring single-cell omics expertise to our Epigenetics Centre, looking forward to all exciting interactions.
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BarcoLab@BarcoLab7 Mar 2024
We're thrilled to share our latest paper on the role of Kdm1a preserving chromatin compartimentalization and gene silencing! You can check it in the link down below: 👇🏻 nature.com/articles/s41467-0… Don’t miss it! @Beatriz_dBlanco @SergioNi92 #neuroepigenetics #Kdm1a 🧠

Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related...

Nature Communications - Kdm1a is a histone demethylase implicated in intellectual disability. Here, the authors show that removing Kdm1a in neurons of the adult mouse forebrain disrupts silencing...

nature.com
Instituto de Neurociencias UMH-CSIC@NeuroAlc7 Mar 2024
🔥A new study led by @BarcoLab at @NeuroAlc is now published on @NatureComms 🙌 Researchers have determined the role of the Kdm1a protein in maintaining the neuronal identity and relationship with age progression More info 👇 in.umh-csic.es/en/articulos/…
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EMBO workshop on "Chromatin dynamics and nuclear organization in genome maintenance". Great line-up of speakers, slots for selected talks, this will be a great meeting. Do not forget the deadline April 1st! meetings.embo.org/event/24-c… #EMBOchromatinDynamics

Chromatin dynamics and nuclear organization in genome maintenance

Maintenance of genome integrity lies at the heart of cell homeostasis. While DNA repair mechanisms have received significant attention since more than half a century, the contribution of the chromati…

meetings.embo.org
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SRRM2 splicing factor modulates cell fate in early development ⁦@apombo1⁩ ⁦@LabPombo⁩ biorxiv.org/content/10.1101/…
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Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level biorxiv.org/cgi/content/shor… #bioRxiv
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Our perspective on epigenetic regulatory layers of the 3D nucleus is out in @MolecularCell! doi.org/10.1016/j.molcel.202…. A solid teamwork with @domSzabo and @apombo1; @LabPombo. 1/3
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here it is- read about 3D virtual tissue blocks, metastasis-lymph node boundaries and unlocking molecular mechanisms in 3D. biggest congratz to the entire team. Open-ST: High-resolution spatial transcriptomics in 3D | bioRxiv biorxiv.org/content/10.1101/…

Open-ST: High-resolution spatial transcriptomics in 3D

Spatial transcriptomics (ST) methods have been developed to unlock molecular mechanisms underlying tissue development, homeostasis, or disease. However, there is a need for easy-to-use, high-resolu...

biorxiv.org
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🚀 Exciting update from VoltRon! Automated image alignment across Visium and Xenium platforms is now possible. 🧬💻 @10xGenomics #spatialbiology @opencvlibrary bioinformatics.mdc-berlin.de…
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Check out the upcoming Cold Spring Harbor meeting on Genome Organization & Nuclear Function, Apr 20 – May 4, 2024, on advances in spatial and temporal aspects of nuclear structure & function. We look forward to seeing you! @WickstromLab @jane_skok @belmont_andrew @cshlmeetings
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Join us at our 12th @cnag_eu Symposium! Great speakers 😜😅👇🏻
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PomboLab retweeted
BarcoLab@BarcoLab2 Oct 2023
This summer @Rafalcala2 and @SergioNi92 had the opportunity to visit @LabPombo at @BIMSB_MDC in Berlin! Such an stimulating experience!
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2 PI Positions Open in Biology and Biomedicine, broadly defined - #LTRI @SinaiHealth @UofT, in Toronto. Part of an exciting growth phase at #LTRI. Apply at apply.interfolio.com/130205. Women and racialized individuals are particularly encouraged to apply. Deadline Oct 15. Please RT!
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nomo@kerstinbys3 Jun 2023
The Genome in Space and Time, the International Nucleome Consortium's Symposium. Join us in beautiful Corfu ! short talk available inc-cost.eu/corfu-2023/ @INC_COST
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I am very happy to announce the full program for the 2023 #GRS on #GenomeArchitecture. We have many exciting talks as well as a career panel with people from different career paths! There is still time to sign up and join! grc.org/genome-architecture-… #GRC #Chromatin
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PomboLab retweeted
BarcoLab@BarcoLab31 Mar 2023
Awesome meeting, with excellent speakers and great synergies. @BarcoLab @LabPombo @LonieRWelch
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Teif Lab@TeifLab8 Mar 2023
xitter.cf/Co_Biologists/status/1…
The Company of Biologists@Co_Biologists7 Mar 2023
Applications are now open for funded early-career researcher places at our Workshop 'Single Cell View 3D Genome Architecture' organised by David Lando, Tim Stevens & Srinjan Basu @srinjan_basu. Find out more and apply at biologists.com/workshops/nov… #BiologistsWorkshops
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