@WickstromLab

Science & fun from the lab of Sara Wickström at the Max Planck Institute for Molecular Medicine & U of Helsinki. Stem cells and mechanical forces. Tweets by SW

 Münster, Germany
mpi-muenster.mpg.de/660820/wickstrom
Joined December 2017
  • Tweets1.9K
  • Following688
  • Followers3.7K
94Media
How do #stemcells integrate information to make fate decisions? Check out our latest preprint where we find that growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to determine whether to retain or exit #pluripotency🧵👇biorxiv.org/content/10.1101/…
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Finally out in print! Check out our study on multiparameter imaging to reveal cancer cell state-dependent crosstalk with stroma that determines patient outcome 👇
Cell@CellCellPress
13 Dec 2024
In the latest issue! Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer dlvr.it/TGmjZ8
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Are you looking for a postdoc opportunity to conduct ground-breaking research with excellent mentorship and supportive colleagues? Look no further! I wholeheartedly recommend 👇
MPI Molecular Biomedicine@MPI_Muenster
20 Nov 2024
We are looking for a: POSTDOC (M/F/D) Interested in implementing cutting-edge technologies, developing new tools, and their integration with spatial transcriptomics and mechanical measurements? Then apply 'til Dec. 31, 2024! jobs.mpi-muenster.mpg.de/job…
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Piezo1 balances membrane tension and cortical contractility to stabilize intercellular junctions and maintain epithelial barrier ... biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Looking for #mechanobiology enthusiasts for an exciting new project - apply and spread the word! 🤩
MPI Molecular Biomedicine@MPI_Muenster
20 Nov 2024
We are looking for a: POSTDOC (M/F/D) Interested in implementing cutting-edge technologies, developing new tools, and their integration with spatial transcriptomics and mechanical measurements? Then apply 'til Dec. 31, 2024! jobs.mpi-muenster.mpg.de/job…
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Check out our latest preprint where we show that the mechanosensitive channel Piezo1 balances membrane and cortex tension for timely assembly and stability of intercellular junctions 🤩 Congratulations @Ahxanjaved and team 🎉 biorxiv.org/content/10.1101/…

Piezo1 balances membrane tension and cortical contractility to stabilize intercellular junctions...

Formation of a bi-directional skin barrier is essential for organismal survival and maintenance of tissue homeostasis. Barrier formation requires positioning of functional tight junctions (TJ) to the...

biorxiv.org
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Highly recommended 👇👇 Great lab and environment!
MPI Molecular Biomedicine@MPI_Muenster
20 Nov 2024
We are looking for a: POSTDOC (M/F/D) Interested in implementing cutting-edge technologies, developing new tools, and their integration with spatial transcriptomics and mechanical measurements? Then apply 'til Dec. 31, 2024! jobs.mpi-muenster.mpg.de/job…
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Bewirb dich bis 01. Dez. 2024! Wir suchen: TECHNISCHE*N ASSISTENT*IN (M/W/D) (BTA, MTA, CTA) Apply until Dec. 1, 2024! We are looking for: TECHNICAL ASSISTANT (M/F/D) (BTA, MTA, CTA) jobs.mpi-muenster.mpg.de/job…ür+Arbeit
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Meet us at Slush: Multivision Diagnostics plans to transform cancer diagnostics and treatment. 🩺 Identifying the unique 'fingerprint' of a patient's tumor will enhance disease prediction and enable personalized care. 🧬💖 #Slush2024 @helsinkiuni helsinki.fi/en/helsinki-inno…

Multivision Diagnostics plans to transform cancer diagnostics and treatment | Helsinki Innovation...

Determining the unique ‘fingerprint’ of an individual patient’s malignant tumour will make it easier to predict the course of the disease and deliver personalised care. A digital pathology innovation...

helsinki.fi
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We have an exciting @sfb1348 lecture with Francesca Spagnoli (Kings Kollege London) about “Progenitor niches in the developing pancreas: regulation of cell fate and beyond” this week. More: uni-muenster.de/SFB1348/en/i… Everyone is welcome!
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H͟e͟a͟d͟ a͟n͟d͟ N͟e͟c͟k͟ O͟n͟c͟o͟l͟o͟g͟y͟ a window to the world of H&N Oncology Novel Method of Cancer Detection: Akin to a tumour fingerprint Read at: linkedin.com/pulse/novel-met… @BSAjaikumar_HCG @theRajGore @drvishalrao @uicc @KaroPunovuori @WickstromLab @CellCellPress

Novel Method of Cancer Detection: Akin to a tumour fingerprint

Given that there is little clarity on how the tumor’s architectural organization, spatial arrangement, and microenvironment impact pathogenesis, the clinical need for better molecular understanding...

linkedin.com
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Wickstrom-Lab retweeted
Cell Press@CellPressNews
1 Nov 2024
In this Q&A, stem cell biologist Dr. Sara A. Wickström emphasizes the value of collaboration and gives advice on how to combat public skepticism of science. #CP50 #50ScientistsThatInspire Read the full interview: cell.com/news-do/50-inspirin…
Quote by Dr. Sara A. Wickström: "I hope that my best discoveries still lie ahead."

ALT Quote by Dr. Sara A. Wickström: "I hope that my best discoveries still lie ahead."

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Fantastic piece of work showing the POWER of combining epithelial and mesenchymal cell states and image mapping to predict clinical cancer outcomes! Congratulations to @KaroPunovuori @WickstromLab and the entire team! Exciting new direction!
Wickstrom-Lab@WickstromLab
28 Oct 2024
Excited to share our latest work on an image analysis paradigm that combines cell state and morphology analyses of patient biopsies at single cell resolution to uncover clinically relevant head-and-neck #cancer phenotypes! @CellCellPress cell.com/cell/fulltext/S0092… tweetorial👇
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#AI meets diagnostics: new imaging analysis @MPI_Muenster @Wickstromlab combines #AI & cell staining to reveal patterns in head & neck tumours, aiming to improve prognosis & treatment strategies!🧪 mpg.de/23642984/1024-vasb-ne… #CancerResearch

Comprehensive diagnosis of head and neck tumors

A new method can be used to predict how a cancer will progress

mpg.de
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New imaging analysis technique revolutionises diagnostics of head and neck cancers. A study developed a new technique to accurately analyse the properties of cancer cells and the surrounding tissue at the level of individual cells. @WickstromLab helsinki.fi/en/news/cancer/n…

New imaging analysis technique revolutionises diagnostics of head and neck cancers | University of...

A study developed a new technique to accurately analyse the properties of cancer cells and the surrounding tissue at the level of individual cells. This innovation enables a more comprehensive...

helsinki.fi
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Tutkimusryhmämme on kehittänyt uuden analyysimenetelmän syövän täsmädiagnostiikkaan. Toivomme että tämä parantaa tulevaisuudessa potilaiden elämänlaatua ja ennustetta. Lue lisää täältä 👇
University of Helsinki
@helsinkiuni
30 Oct 2024
Uusi teknologia luo syöpäpotilaan solunäytteistä yksilöllisen "sormenjäljen", jonka perusteella voidaan arvioida syövän ennustetta ja hoitovastetta. Tulokset ovat läpimurto syövän kehityksen ymmärtämisessä ja diagnostiikassa. @WickstromLab @HelsinkiUniMed helsinki.fi/fi/uutiset/syopa…

Uusi kuvantamisanalyysi mullistaa pään ja kaulan alueen syövän diagnostiikan | Helsingin yliopisto

Tutkimuksessa kehitettiin uusi menetelmä, jonka avulla voidaan tarkasti analysoida syöpäsolujen ja niitä ympäröivän kudoksen ominaisuuksia yksittäisten solujen tasolla. Innovaatio mahdollistaa pään...

helsinki.fi
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Um Verlauf und Therapieansprechen bei #KopfHalsKrebs besser vorherzusagen, analysiert eine von @Wickstromlab an der 🇫🇮 @helsinkiuni, mit 🇫🇮 @UniTurku und 🇩🇪 @MPI_Muenster entwickelte Technik Krebszellen und umgebendes Gewebe auf Einzelzell-Ebene. dlvr.it/TFtT88

Bessere Diagnostik von Kopf- und Halstumoren durch neues Analyseverfahren

Krebserkrankungen des Kopfes und Halses gehören weltweit zu den zehn häufigsten Krebsarten. Kopf-Hals-Tumoren machen etwa 3-5 % aller Krebsfälle aus, wobei Plattenepithelkarzinome die vorherrschende...

healthcare-in-europe.com
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Wickstrom-Lab retweeted
ISSCR@ISSCR
29 Oct 2024
🎉Congratulations to ISSCR Member and member of the ISSCR Scientific Programs Committee Sara Wickström for being named one of #50ScientistsThatInspire! @WickstromLab @CellPressNews ow.ly/rHFY50TVpSK
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Very impressive work from the ⁦@WickstromLab⁩ Congratulations to @KaroPunovuori & collaborators!!! @IvaskaLab : “Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head and neck cancer” cell.com/cell/fulltext/S0092…

Multiparameter imaging reveals clinically relevant cancer cell-stroma interaction dynamics in head...

An image analysis pipeline that integrates cell-state and morphological markers identifies clinically relevant tumor phenotypes and cell-state-dependent interplay between tumor and stroma that drives...

cell.com
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1/4 After weeks of crunchtime I'm excited to start thinking about the future!🌟 I’m looking to establish a group focused on Collective #CellMigration, #Morphogenesis, #DevBio/#CellBio. We're flexible on location, with a preference for Europe. Any suggestions?🤔email:[email protected]
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Meeting alert! Registration deadline 15th November! Join us next year @TheCrick in London for The Beddington Dev Bio symposium. A stellar lineup of speakers, additional talks to be selected from submitted abstracts. You don't want to miss this crick.ac.uk/whats-on/the-3rd…
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