📈 Is there an optimal blood ketone level for weight loss on a ketogenic diet? This study followed 217 adults with overweight or obesity who measured their blood ketones and body weight every day during a 14-day ketogenic diet. The goal was to identify the blood ketone level most strongly associated with successful weight loss. Researchers found: ✅ A blood β-hydroxybutyrate (BHB) level of ≥0.5 mmol/L was the strongest predictor of weight loss. ✅ Participants reached this level in an average of 7.7 days, with nearly 60% achieving it between days 5 and 8. ✅ Average weight loss was 7.0% in just 14 days. ✅ Every additional day spent with BHB ≥0.5 mmol/L was associated with about 0.5% greater weight loss. ✅ The Mediterranean ketogenic diet with phytoextracts helped participants reach ketosis faster than the classical ketogenic diet. The findings suggest that monitoring blood ketones may help optimize weight loss by ensuring nutritional ketosis is achieved and maintained. — Paoli A, Cerullo G, Paoli S, Charrier D, Givralli J, Bianco A, Boccuzzo G, Belloni P, Cenci L, Moro T. Defining a ketone threshold for weight loss: evidence from 14 day daily β-hydroxybutyrate monitoring in 217 subjects on a ketogenic diet. Nutr Diabetes. 2026 @antoniopaoliMD 📌 Link to study: doi.org/10.1038/s41387-026-0… 📌 Find more research summaries on our website: keto-mojo.com/research/ #KetogenicDiet #Ketosis #WeightLoss #MetabolicHealth

A recent meta-analysis suggests that ketogenic diets may improve both hormonal and metabolic outcomes in women with polyendocrine metabolic ovarian syndrome (PMOS; formerly PCOS) and overweight or obesity. Researchers analyzed data from 11 studies (4 randomized controlled trials and 7 pre-post intervention studies) evaluating ketogenic dietary interventions, including very-low-calorie ketogenic diets and other carbohydrate-restricted approaches. Key findings: 🔹 Total testosterone decreased significantly 🔹 Sex hormone-binding globulin (SHBG) increased significantly 🔹 LH and the LH/FSH ratio improved 🔹 BMI, waist circumference, body fat, fasting insulin, and insulin resistance decreased 🔹 Triglycerides and total cholesterol decreased, while HDL cholesterol increased 🔹 Several studies also reported improvements in menstrual regularity, ovulation, and fertility-related outcomes Interestingly, reductions in testosterone were not explained by changes in body weight or insulin levels, raising the possibility that ketosis may influence ovarian function through additional mechanisms. While the findings are very promising, larger randomized controlled trials are needed to confirm these effects. — Maseroli E, Alfaroli C, Cirillo M, Ravelli SA, Lambrinoudaki I, Focardi M, Virgili G, Vignozzi L. Ketogenic diet as a therapeutic intervention for biochemical hyperandrogenism in PCOS women with obesity or overweight: a meta-analytic study. Journal of Endocrinological Investigation. 2026 📌 Link to study: doi.org/10.1007/s40618-026-0… 📌 Find more research summaries on our website: keto-mojo.com/research/ #PCOS #PMOS #WomensHealth #MetabolicHealth #KetogenicDiet

Houston, let’s increase your metabolic intelligence! 🧠 Keto-Mojo is heading to Pompa LIVE. Stop by our booth to have your glucose and ketone levels tested, and talk with our team. Led by @DrDanPompa, the event brings together health educators, practitioners, and wellness advocates to explore connections between cellular function, energy, brain health, hormones, environmental exposures, and chronic symptoms. The announced lineup includes Dr. Daniel Pompa, metabolic health educator @THEBENAZADI, brain-health pioneer Dr. Patrick K. Porter, Dr. Rafael Gonzalez, Dr. Olivia Pompa, and wellness entrepreneur @JennyMcCarthy, and many more. 📅 October 16–18, 2026 📍 The Westin Houston Memorial City | Houston, TX We’ll see you in Vendor Village! 👉 Explore Pompa LIVE: pompalive.com/ #MetabolicHealth #MetabolicIntelligence #KetoMojo #KetogenicDiet

🧠 This #WorldMentalHealthDay, we’re shining a light on an evolving area of research: the link between metabolic and mental health. In this @lowcarbusa presentation, psychotherapist @KetoCounselor Nicole Laurent, LMHC, explores how individuals interested in ketogenic metabolic therapy can connect with a network of professionals who are building a more collaborative approach to mental healthcare. ▶️ Watch Building a Ketogenic Support System – Utilizing Professional Networks for Mental Health Treatment: keto-mojo.com/lowcarbusa_vid… #MentalHealth #MetabolicHealth #MetabolicPsychiatry #KetogenicTherapy #LowCarb #KetoMojo

The last day of The Ketogenic Foundation's Frontiers in Metabolic Health & Nutritional Ketosis might be over, but the work is just beginning. Three things you can do to keep the conversation going long after the conference ends: 1. Share your learnings with someone you know. The Ketogenic Foundation offers educational resources at no cost. 2. Bring what you learned into your everyday lives and help the science advance in clinical practice. 3. Engage future researchers and clinicians by sharing educational materials with students, professors, and clinical coordinators. Dorian Greenow, Gemma Kochis, Stephen Phinney Gary, Taubes, Jeff Volek, Brittanie Volk, PhD, RD, John Schoonbee, MD, Robert Ratner, MD, Doug Carlson, Richard Wood, Ph.D., Society of Metabolic Health Practitioners, Doug Reynolds, Pam Devine @garytaubes @john_schoonbee @TheSMHP @DougieReynolds @LCPamDevine We can't wait to see the collaborations this event sparks. 👉 To learn more about The Ketogenic Foundation and resources available: lnkd.in/g8MV8dvA #NutritionalKetosis #MetabolicIntelligence #Ketosis #KetoMojo

South Africa, Keto-Mojo is heading to the World Nutrition Summit! From 14–16 October 2026, The Noakes Foundation will bring together researchers, clinicians, and practitioners at Hazendal Wine Estate in Stellenbosch to explore nutrition, metabolic health, and chronic disease. Speakers include @ProfTimNoakes, @AKoutnik, @doctorkiltz , @KackleyMLPhD, @MariaEmmerich, Dr. Hassina Kajee, and @GrassBased. Keto-Mojo founder Dorian Greenow will also take the stage October 14 from 12:15 pm to 1 pm to present "Metabolic Flexibility: The Foundation of Longevity and How to Read the Signals That Drive It", and we look forward to connecting with delegates throughout the summit. October 14–16, 2026 Hazendal Wine Estate | Stellenbosch, South Africa We look forward to seeing you! The programme is now available. Explore the sessions and plan your summit experience: thenoakesfoundation.org/wns2… Join us in person or virtually. Use code WNS26-01 for 20% off your ticket. Book here: quicket.co.za/.../361582-wor… #MetabolicHealth #MetabolicIntelligence #KetoMojo #KetogenicDiet

Continuous glucose and ketone monitoring was recently approved by the FDA for people ages 2+ living with diabetes, an important milestone for metabolic health. The ability to see glucose and ketone dynamics continuously opens up new possibilities, particularly for people who need high-frequency information to make important health decisions. This reinforces something we’ve believed at Keto-Mojo for a long time: glucose alone doesn’t always tell the whole story. Looking at glucose alongside ketones and understanding your Glucose Ketone Index (GKI) can provide additional context about your metabolic state. Continuous and point-in-time monitoring can serve different needs. Continuous monitoring can be valuable when high-frequency tracking matters. Fingerstick blood testing provides an intentional, on-demand checkpoint when you want to understand where you are at a specific moment. We applaud the continued innovation happening in metabolic monitoring and the greater visibility it can give people into their own metabolic health. Townsend Letter explores what continuous ketone monitoring could mean: townsendletter.com/continuou… #MetabolicHealth #Ketones #Glucose #GKI #Diabetes #HealthTechnology

Day 3 of The Ketogenic Foundation's inaugural Frontiers in Metabolic Health & Nutritional Ketosis, and we're keeping the momentum going! Last night's poster session brought the science to life! On stage today, Caroline Roberts, MD, Laura Saslow, PhD, Guido Frank, DM, @AKoutnik, @GeorgiaEdeMD and many more shared research and clinical insights, giving us a fresh perspective to take home. One more day to go! #KetogenicLifestyle #Ketosis #MetabolicIntelligence

Starting a ketogenic diet comes with a learning curve, and most of us wish we'd known a few things before we began. In this article, Christi Terjesen, Keto-Mojo’s Head of Marketing, shares eight lessons she's learned over the past decade. Whether you're new to keto or have been following it for years, you're likely to find a few helpful takeaways. 🔗 keto-mojo.com/blog/what-i-wi… #KetoTips #LowCarbLiving #NutritionalKetosis #MetabolicHealth

Day 2 at Frontiers in Metabolic Health and Nutritional Ketosis, and the energy keeps building! 🙌 Researchers, clinicians, and attendees are sharing discoveries, sparking ideas, and moving the conversation around ketogenic living forward. The science is coming to life! Can't wait for day 3. #MetabolicHealth #Ketones #NutritionalKetosis #MetabolicIntelligence @john_schoonbee @DominicDAgosti2 @KetoCounselor @TheSMHP

Can a low-carb ketogenic diet be safely used in patients with heart failure and obesity? This retrospective study followed 125 adults with heart failure, including both reduced (HFrEF) and preserved (HFpEF) ejection fraction, who adopted a ketogenic diet for at least one year in a clinical weight-loss setting. Key results: ▪️ Median weight loss: 24.7 lb (11.2 kg) over approximately two years ▪️ HF hospitalizations dropped by about 50% (rate ratio = 0.5), especially in HFpEF ▪️ HDL cholesterol increased, triglycerides decreased; LDL and total cholesterol remained stable ▪️ 45% of patients with type 2 diabetes reduced their insulin dose ▪️ No significant changes in ejection fraction, diastolic function, or mitral regurgitation ▪️ ACE inhibitor, ARB, or ARNI doses were reduced in 39% of HFrEF patients These findings suggest a ketogenic diet may be a safe, effective strategy for weight loss and metabolic improvement in patients with heart failure and obesity, while also lowering hospitalization risk. While randomized trials are needed to confirm long-term safety and benefits, these findings are encouraging. — Moseley GA, Yancy WS Jr, Westman EC, Selvaraj S, Harrington J. Retrospective Review of the Safety and Effectiveness of a Low Carbohydrate Ketogenic Diet Intervention in Patients with Overweight or Obesity and Heart Failure. Journal of Cardiac Failure – Intersections. 19 September 2025. @drericwestman 📌 Link to study: sciencedirect.com/science/ar… 📌 Find more research summaries on our website: keto-mojo.com/research/ #KetogenicDiet #HeartFailure #Obesity #Cardiology #MetabolicHealth

Can a ketogenic diet influence tumor biology in endometrial cancer? In a randomized feasibility trial, women with overweight or obesity and newly diagnosed endometrial cancer followed either a very low-carbohydrate ketogenic diet (VLCD) or their usual diet for approximately 4 weeks before surgery. The ketogenic diet proved feasible and well tolerated: 🔹 91% of provided ketogenic meals were consumed 🔹 Nutritional ketosis was achieved within days, with mean β-hydroxybutyrate (BHB) levels reaching ~1.9 mmol/L 🔹 Only mild adverse events were reported; no serious adverse events occurred Participants in the VLCD group also experienced notable metabolic changes: 🔹 5.5% weight loss in ~4 weeks 🔹 22% lower fasting glucose 🔹 60% lower fasting insulin 🔹 Reductions in HbA1c, C-peptide, IGF-1, and leptin Beyond systemic metabolism, researchers observed reduced tumor PI3K signaling and increased CD8⁺ T-cell infiltration at the tumor margin. This was a small feasibility study and was not designed to assess cancer outcomes. However, the findings suggest that short-term carbohydrate restriction may influence both metabolic and tumor-related pathways in endometrial cancer. — Dantas E, Hootman KC, Moyer J, Tomberlin M, Curran K, Ramesh B, Price H, Kim J, McPherson AC, Hurd MA, Zhu YS, Plodkowski AJ, Nagase E, Tsomides A, Cuevas BM, Martin ML, Nguyen J, Bennetti G, Botero Rodriguez G, Chang K, Mezzancello M, Gardner GJ, Broach V, Mueller JJ, Sonoda Y, Zivanovic O, Leitao MM Jr, Iasonos A, Soldan K, Carthew K, Hom V, Villamater FN, Chaari RR, Gorski K, Sigouros M, Aghajanian C, Elemento O, Cantley LC, Hopkins BD, Weigelt B, Ellenson LH, Hacker K, Abu-Rustum NR, Makker V, Goncalves MD. Very low-carbohydrate ketogenic diet in treatment-naïve women with endometrial cancer and overweight: a randomized feasibility study. Nat Commun. 2026. 📌 Link to study: doi.org/10.1038/s41467-026-7… 📌 Find more research summaries on our website: keto-mojo.com/research/ #Ketosis #EndometrialCancer #MetabolicHealth #CancerResearch

The future of metabolic health is being shaped right now—and the people advancing the science are coming together in Dallas. Join us for Frontiers in Metabolic Health & Nutritional Ketosis, October 4–7, 2026, at the Sheraton Dallas Hotel. Presented by The Ketogenic Foundation, this conference will unite leading clinicians, researchers, dietitians, educators, healthcare innovators, and advocates for four days of emerging research, practical clinical insights, and meaningful collaboration. Hear from respected experts as we explore the science and application of ketogenic nutrition and metabolic therapies. If you are committed to improving health through evidence-based nutrition, this is a conversation you will not want to miss. I would love to see you there. Learn more and register: conference.ketogenicfoundati… #MetabolicHealth #KetogenicNutrition #NutritionalKetosis #KetogenicTherapies #NutritionScience #HealthcareInnovation #KetogenicFoundation

When weight loss is matched, does diet composition still matter? In this randomized clinical trial, 55 adults with obesity, prediabetes, and fatty liver were assigned to ketogenic, Mediterranean, or very-low-fat plant-forward diets. Metabolic outcomes were compared after ~10% weight loss. 🔹 Liver fat fell 67% with the ketogenic diet vs 45% with both other diets. 🔹 Hepatic insulin sensitivity improved 2–3 times more with the ketogenic diet. 🔹 24-hour insulin levels fell 74%, compared with 44% and 27% on the Mediterranean and very-low-fat diets. 🔹 Prediabetes remission occurred in 50% of the ketogenic group vs 29% and 7% in the other groups. The findings suggest that macronutrient composition may influence the metabolic benefits of weight loss, particularly liver and glucose metabolism. — Petersen MC, Smith GI, Farabi SS, Palacios HH, Shankaran M, Hellerstein MK, Patterson BW, Klein S. Effect of diet macronutrient content on the cardiometabolic response to weight loss: A randomized clinical trial. _Cell Metab._2026;38:1–12 📌 Link to study: cell.com/cell-metabolism/ful… 📌 Find more research summaries on our website: keto-mojo.com/research/ #KetogenicDiet #MetabolicHealth #Prediabetes #FattyLiver #Research

That’s a wrap on the Health Optimisation Summit! Our biggest takeaway? The more we understand our individual biology, the more metabolically intelligent we become - empowering us to make more informed decisions about our health. Thank you to everyone who stopped by, tested with us, asked questions, and shared your stories. We loved connecting with you! And a huge thank you to @TimBiohacker, the entire @HOsummit team, all the exhibitors, and the incredible volunteers who made such a dynamic weekend possible. See you next year, London! 🇬🇧 #HealthOptimisationSummit #Biohacking #MetabolicHealth #Longevity #DataDrivenHealth #MetabolicIntelligence

Metabolic health doesn’t stop at your metabolism. That idea took center stage at the @HOsummit where Keto-Mojo founder Dorian Greenow presented “How to Change Nearly Every Cell in Your Body.” He packed the house, exploring how metabolic health impacts the entire body and how tracking your biomarkers can make it measurable and personal. What’s one thing you learned at this year’s Summit that changed how you think about your health? #HealthOptimisationSummit #Biohacking #MetabolicHealth #Longevity #DataDrivenHealth #MetabolicIntelligence

In case there was any question — yes, we have the best co-founder. Happy Birthday, Gemma! #KetoMojo #Ketogether #WhatsYourMojo

Can a nutrition-focused, remote care program reduce liver disease risk in high-risk adults? In a large U.S. matched cohort study (n=10,062), Virta Individualized Nutrition Therapy (VINT) – a telemedicine program designed to achieve nutritional ketosis and promote metabolic health – was compared with usual care. Over an average of 2 years, the VINT participants had a consistently lower incidence of liver-related outcomes: 🔹 ~39% lower relative risk of any liver-related diagnosis (HR 0.61) 🔹 ~62% lower relative risk of progressive liver disease (MASH and beyond; HR 0.38) 🔹 ~67% lower relative risk of advanced liver disease (HR 0.33) 🔹 ~75% lower relative risk of liver-related complications (HR 0.25) 🔹Greater weight loss was also associated with lower risk: ≥15% weight loss, ~34% lower relative risk (HR 0.66) Despite similar medication use and healthcare utilization, fewer liver-related events were observed in the VINT participants. These findings support a lifestyle-first, metabolically targeted approach as a scalable strategy to reduce liver disease risk. — Athinarayanan SJ, Wolfberg AJ, Shanmugam PV, Hameed BA, Bonacini M. Reduced risk of liver-related events among patients receiving individualized nutrition-focused remote care in the United States. Hepatology. 2026; 10.1097 📌 Link to study: journals.lww.com/hep/fulltex… 📌 Find more research summaries on our website: keto-mojo.com/research/ #MetabolicHealth #KetogenicDiet #Ketosis #MASLD #NutritionScience