Henderson Neurodegenerative Disease Lab. Misfolded proteins, disease processes, therapeutic development. PD and AD pathogenesis š¬š§
Grand Rapids, MI
Joined October 2019
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HND_Lab retweeted
Findings from @HND_Lab, published in @NatureComms, identified a molecular āfingerprintā that marks brain cells vulnerable to Lewy bodies, key hallmarks of #Parkinsons & Lewy body dementia. The image depicts cells in yellow & pathology in magenta.
vai.org/henderson-lewy-bodieā¦
HND_Lab retweeted
@VAInstitute is hiring faculty in the Department of Neurodegenerative Science! Come join this exceptional team!
nature.com/naturecareers/jobā¦
HND_Lab retweeted
@VAInstitute is hiring faculty in the Department of Neurodegenerative Disease! Come join us in this highly-collaborative institute with excellent support!
nature.com/naturecareers/jobā¦ š§ š§Ŗ
HND_Lab retweeted
This network of neurons (in blue) is helping the @hnd_lab study #Parkinsons. By understanding what goes wrong on the cellular level, they hope to find ways to impede disease progression ā something not possible with current treatments. Learn more at hendersonlab.vai.org
HND_Lab retweeted
So excited our single-cell transcriptomic survey of the adult human brain is on bioRxiv! @slinnarsson @MossiAlejandro @ka_wai_rine @ErnestArenasSWE A really fun collaboration with Rebecca Hodge, Trygve Bakken, Ed Lein and others at the @AllenInstitute doi.org/10.1101/2022.10.12.5ā¦
HND_Lab retweeted
As part of our commitment to supporting and investing in postdoctoral trainees, Van Andel Institute is increasing #postdoc starting salaries to $70,000 a year. Read more: vai.org/postdoc-support
HND_Lab retweeted
This is an excellent paper looking in detail at neuronal vulnerability to tau pathology in Alzheimer's disease! Great to see this out following the preprint in 2020.
cell.com/neuron/fulltext/S08ā¦
HND_Lab retweeted
This was a great opportunity to write a collaborative review with @BrundinPatrik, Jim Surmeier and colleagues. We hope it will serve as a framework for thinking about integration of selective vulnerability and connectivity in Parkinson's disease progression.
New #openaccess review on critical assessment of why some brain regions exhibit #synuclein pathology and others do not in #Parkinson disease and #DLB. The roles of #connectome and selective vulnerability.
@ScienceofPD @WorldPDCongress
@MXHend
sciencedirect.com/science/arā¦
HND_Lab retweeted
A poignant description of dementia with Lewy bodies from the patient/neurologist perspective. journals.lww.com/continuum/Fā¦
HND_Lab retweeted
Johnās impact will continue to be seen for generations through all the scientists he trained and mentored.
John Q. Trojanowski, mentor, friend.
Larger than life leader in neurodegenerative disease research, probing intellect, limitless enthusiasm and energy, ever present personality.
I will miss you. #RIP
HND_Lab retweeted
New research from @BenHobs3 @soldier_dave @psimslab & colleagues explores subcellular proteomics of dopamine neurons in the mouse brain & reveals axonal enrichment of proteins encoded by #Parkinsons-linked genes (figures are next level!)
elifesciences.org/articles/7ā¦
HND_Lab retweeted
Learn more about Van Andel Institute's summer #internship program at our upcoming Zoom office hours! The next session is from noon to 2 p.m. ET Monday, Nov. 29. Click here to register: bit.ly/3DPJQBd
HND_Lab retweeted
Happy to share this preprint from our lab
A novel mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein. Congratulations to
@SenThangaraj and @MahulALM and other members of the Lashuel, @FrankSobott and @mz_science labs. biorxiv.org/content/10.1101/ā¦
HND_Lab retweeted
Van Andel Institute Graduate School is a global destination for doctoral students. Join us on Nov. 12 for a free webinar to learn more about our #research #PhD program in molecular and cellular #biology: bit.ly/3BJYxDR @sgraingerPhD @DrRGJonesLab #highed #gradschool
HND_Lab retweeted
.@ASAP_Research has awarded a team of scientists from VAI, @Yale & @Penn a $9 million grant to identify areas and cell types in the brain that may be particularly vulnerable to #Parkinsons disease. Congrats to VAIās @MXHend & collaborators! bit.ly/3BgyrIq
HND_Lab retweeted
Very excited to join #ASAP_CRN and work with @BiedererLab, @DaniSBassett, @mjhigley, and Elena Gracheva to understand circuit and cell level vulnerability in Parkinson's disease!
Excited to announce that 14 new teams will be joining the ASAP Collab Research Network (#ASAP_CRN) with a focus on #circuitry and brain-body interactions connected to #Parkinson's.
Meet the #ASAPGrantees! parkinsonsroadmap.org/researā¦
HND_Lab retweeted
Learn more about Van Andel Institute Graduate School's Ph.D. program in molecular and cellular biology at the @CareerEco Biomed Virtual Grad School Fair on Oct. 20! Details and registration: bit.ly/3vmfpiF
HND_Lab retweeted
Grand Challenges in Parkinson's Disease virtual conference is this week!
We have a focus this year on GBA1 and LRRK2. Registration may be technically closed, but you can still get in if you email Kim (see website)!
@VAInstitute
grandchallengesinpd.org/
HND_Lab retweeted
Do you research Parkinson's disease? GBA1 or LRRK2? Have interesting data to present? Submit an abstract to Grand Challenges in PD @VAInstitute. Deadline is September 20.
grandchallengesinpd.org/postā¦