@DrRGJonesLab

Immunology/cancer researcher. Chair, Metabolism Dept at @VAInstitute @VAIMetabolism. Former @McGillU @UofT. GRR/YYZ. Opinions are my own

Grand Rapids, MI
Joined February 2010
The Jones lab @VAInstitute is recruiting postdoctoral fellows interesting in studying how nutrition impacts anti-tumor immunity. vai.wd1.myworkdayjobs.com/en…
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How exercise decreases the risk of cancer and cancer- related mortality by reducing immunosenescence and inflammaging sciencedirect.com/science/ar…
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Replying to @EricTopol @Nature
Commentary on diet caloric restriction vs cancer nature.com/articles/d41586-0… and importance of cancer metabolism statnews.com/2025/12/15/onco…
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How a restricted diet (DR) improves the immune response to cancer and success of immunotherapy in the experimental model. T cell metabolic reprogramming @NatMetabolism nature.com/articles/s42255-0…
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New! Online now: Restricting lipid accumulation in tumor-infiltrating neutrophils mediates caloric restriction-induced anti-cancer effects dlvr.it/TPlGV5
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Human gut M cells resemble dendritic cells and present gluten antigen @Nature @HansClevers nature.com/articles/s41586-0…
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All in all, this work suggest that the anti-tumor effects of calorie restriction works in part by boosting anti-tumor T cell responses. Our study adds to the exciting new work out recently indicating that nutrition plays an important role in immunity against cancer.
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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumor immunity and immunotherapy responses @NatMetabolism @DrRGJonesLab @VAInstitute nature.com/articles/s42255-0…
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How it started How it’s going
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Epigenetic scarring after chronic infection or cancer can lock immune cells into a dysfunctional state. Here, @Hazemghoneim11 & team @OhioState develop an in vitro model of terminal CD8+ T cell dysfunction that better mimics in vivo exhaustion. insight.jci.org/articles/vie…
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#GLP1 medicines now address weight loss and other health conditions through innovative formulations and expanded indications, highlighting key questions about their efficacy and safety. ja.ma/4nHJMKw
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