@wormdoc1

Professor of Cell and Developmental Biology, Grandad, Swimmer

 Vanderbilt Univ.,Nashville, TN
lab.vanderbilt.edu/miller-lab/
Joined June 2009
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  • Followers417
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Who would have thought epithelial cells set cortical tension using information from a cell surface receptor? See our bioRxiv preprint for details - biorxiv.org/content/10.1101/…

After wounding, a G-protein coupled receptor restores tension to epithelial cells in a dynamic...

The maintenance of epithelial barrier function is due in part to cellular tension, with cells pulling on their neighbors to maintain epithelial integrity. Wounding interrupts cellular tension and...

biorxiv.org
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Congratulations Erik Jorgensen of @UUtah, newly inducted #NASmember! #NAS160 #neuroscience #physiology
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Congratulations Yi Shi Jin of @UCSanDiego, newly inducted #NASmember! #NAS160 #neuroscience
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David Miller retweeted
Alexander Bae@jalex_bae24 Mar 2023
Check out our newest preprint! doi.org/10.1101/2023.03.23.5… Releasing C. elegans dauer connectome, the last piece of the C. elegans connectomes across development. Work led by talented students @HyunsooYim, @dantae_choe with great collaborators. @SNUNow, @EinsteinMed , #SKKU #KBRI 1/n
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Cody J. Smith@cssmity16 Mar 2023
Really excited about our new preprint from the lab about microglia lifespan and cannibalism. Congrats to Hannah Gordon for her hard work! Read more below about the story 👇🧵👇 @ZTSlab biorxiv.org/content/10.1101/…

A paradox promoted by microglia cannibalism shortens the lifespan of developmental microglia

The overproduction of cells and subsequent production of debris is a universal principle of neurodevelopment. Here we show an additional feature of the developing nervous system that causes neural...

biorxiv.org
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Glad to finally share with you the publication of my thesis work ! We sequenced C. elegans transcriptome using @nanopore long-reads to provide a comprehensive analysis of trans-splicing ! Please read our study ! rdcu.be/c6O85
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We are hiring! Looking for a great opportunity to learn molecular genetics, live cell imaging and single cell RNA-Seq? Join us! vanderbilt-university.talent…
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Want to know how synapses are dismantled in remodeling neurons? Check out this exciting work from Andrea Cuentas-Condori and colleagues biorxiv.org/content/10.1101/… @AndreaCuentas91, @VanderbiltCDB, #cellbiology

The Epithelial Na+ Channel UNC-8 promotes an endocytic mechanism that recycles presynaptic compon...

Summary Presynaptic terminals are actively relocated during development to refine circuit function, but the underlying cell biological mechanisms are largely unknown. In C. elegans , the presynaptic...

biorxiv.org
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David Miller retweeted
Isabel Beets@isabelbeets1 Nov 2022
Finally out! Check our new resource of neuropeptide-GPCR interactions in C. elegans. We identify 461 peptide-GPCR pairs that allow mapping peptidergic circuits. See also this application on the worm's peptide connectome doi.org/10.1101/2022.10.30.5… Resource: doi.org/10.1101/2022.10.30.5… 🧵
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New tool available: you can now look at alternative splicing in many neuron types of the worm brain! Access it at splicing.cengen.org (1/7)
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Muy feliz de ser parte de la familia de #HannaGrayFellows Agradecida con todas las personas que se han cruzado en mi camino y de las que he aprendido tanto! Especialmente mis mentores @wormdoc1 @dacolon @PageMcCawLab @Gould_Lab @VGamaLab & Ege Kavalali. Gracias!
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Very proud of our latest publication on a great collaboration with Kang Shen's lab in Stanford: Endocytosis in the axon initial segment maintains neuronal polarity disq.us/t/4a08nb5
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Congratulations, Melanie!
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Our latest paper is out in the world! TL;DR: We found that outgrowth and myelination of peripheral nerves requires muscle patterning by tcf15/paraxis. See it here: authors.elsevier.com/a/1fRBc… (1/4)
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Dylan Burnette
@MAG2ART8 Jul 2022
The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes #Science #CellBiology #Cardiotwitter #myotwitter nature.com/articles/s41598-0…
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YogevLab@LabYogev8 Jul 2022
Congratulations to our former postdoc, Dr. Balseiro-Gomez, and current PhD Candidate, Mick Park, for their fantastic contribution to our understanding of microtubule minus-ends in synaptic transport! 🎊 We are proud of your work! authors.elsevier.com/a/1fNY2…
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David Miller retweeted
Macara Lab@LabMacara27 Jun 2022
We are excited to welcome Dr. Neil Dani, PhD, to Vanderbilt Dept of Cell & Developmental Biology, as our newest Assistant Professor - joining an amazing group of junior faculty here!
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Cody J. Smith@cssmity17 Jun 2022
New work from @larngrn11, @michaelrodea, and @camdenhoover3. Congrats for your hard work!
Nature Neuroscience
@NatureNeuro17 Jun 2022
The embryonic zebrafish brain is seeded by a lymphatic-dependent population of mrc1+ #microglia precursors New from @michaelrodea @camdenhoover3 @cssmity and colleagues nature.com/articles/s41593-0…

The embryonic zebrafish brain is seeded by a lymphatic-dependent population of mrc1+ microglia...

Nature Neuroscience - Green and O’Dea et al. identify that the embryonic zebrafish brain is colonized by a population of early-colonizing microglia that are dependent on lymphatic vessels,...

nature.com
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Cody J. Smith@cssmity7 Jun 2022
New publication from the lab😀. This was one of the first projects in the lab. We describe an #oligodendrocyte lineage cell that specifically associates with DRG sensory axons. There were a few surprising findings (see below) and many unanswered questions frontiersin.org/articles/10.…
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Fantastic technique to hopefully study connectivity at a single neuron resolution!
Tony Zador@TonyZador13 May 2022
BARseq can now reconstruct axonal projections at high-throughput! Below: Projections of 100 neurons from a single brain, subsampled (for display purposes) from the 8607 neurons recovered from barcoded viral library injection into auditory cortex. Great work by Li Yuan
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