@Gould_Lab
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We study the coordination & execution of cell ➗ division using 🧬 genetics, 🦠 cell biology, 🔬microscopy, proteomics & more in #Pombe! Tweets from lab members.
Nashville, TN
Joined November 2017
- Tweets263
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- Followers720
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😍
Issue 18 is complete
Explore our ToC: journals.biologists.com/jcs/…
Our cover image shows mutant S. pombe cells lacking ER-PM tethers, with cortical ER in magenta and Duc1-mNeonGreen in cyan. Discover more in the article from Alaina Willet et al. @Gould_Lab.
journals.biologists.com/jcs/…
ALT Journal of Cell Science cover. The image is a live cell image of S. pombe cells expressing a marker for cortical ER (magenta) and Duc1-mNeonGreen (cyan). These cells lack the major ER–PM tethers Scs2 and Scs22 and as a result, the ER is partially separated from the PM and Duc1 localises along the plasma membrane lining the division septum.
Gould Lab retweeted
Alaina Willet, Kathleen Gould and team @Gould_Lab find that Duc1 influences plasma membrane lipid composition and cytokinetic ring anchoring. #OpenAccess
Highlight: journals.biologists.com/jcs/…
Article: journals.biologists.com/jcs/…
ALT Live-cell imaging of Duc1–mNG and mCherry–AHDL in wild-type or scs2Δ scs22Δ cells showing Duc1 is excluded from the cell division site
Gould Lab retweeted
From MBoC
@Gould_Lab report that the FHA domain in one SIP component is necessary & sufficient for SIP spindle pole body (SPB) targeting & function. Cell viability requires SPB SIP localization is transient. Residues unique to its catalytic subunit...
doi.org/10.1091/mbc.E24-04-0…
Gould Lab retweeted
From MBoC
The core spindle pole body scaffold Ppc89 links the pericentrin ortholog Pcp1 to the fission yeast spindle pole body via an evolutionarily conserved interface @Gould_Lab
doi.org/10.1091/mbc.E24-05-0…
Gould Lab retweeted
send your awesome #cleavage stories to @ASCBiology #cellbio2024 for our 8th biannual Cytokinesis subgroup! (stable actomyosin rings and network reconstitution work welcome too!)
please RT for all those last-minute #cell #Biology -ists out there burning the midnight arc lamp!
Gould Lab retweeted
Once again we organize the 8th Frontiers in Cytokinesis subgroup at #CellBio2024 in San Diego. The deadline to submit an abstract to be considered for a talk is August 6. Cytokinesis folks, please consider presenting!
Gould Lab retweeted
In the lab. 8 am Sunday to see the outcome of a genetic screen in S japonicus, made popular by @alebenoit Reminds me of the time in @Gould_Lab Lab meeting tomorrow and want to present my work.
New paper out now with a model for how pericentrin is anchored at the centrosome and spindle pole body! molbiolcell.org/doi/10.1091/…
Gould Lab retweeted
Please feel free to retweet
I have a post-doctoral position to measure cytokinetic forces in collaboration with Justin Molloy in Warwick.
warwick-careers.tal.net/vx/l…
Check out our most recent pub! Transient PP2A SIP complex localization to mitotic SPBs for SIN inhibition is mediated solely by the Csc1 FHA domain | Molecular Biology of the Cell molbiolcell.org/doi/10.1091/…
We are super proud of a recent micropub because the first author is a *high school student* !! Anna Bowman Fletcher (left) spent last semester in the Gould lab through a course at @HarpethHall . Huge thanks to Lesley Turner (in cat sweatshirt) for her mentorship of Anna!
Anna was also recently awarded first place within the Cellular and Molecular Biology division of Middle Tennessee Science and Engineering Fair - and if that wasn't enough - she was also the alternate grand prize winner!!
Read her micropub here on Spg1 alleles in S. pombe!
micropublication.org/journal…
A micropub inspired by @ValWood5 wanting to know the mutations for all the S. pombe alleles in @PomBase - we made a small dent 😅
Characterization of temperature-sensitive alleles of Schizosaccharomyces pombe septation initiation network components #micropublication #biology #data #caltechlibrary #Spombe #PhenotypeData #GeneticScreens #NewFinding #MaterialsAndReagents micropublication.org/journal…
Gould Lab retweeted
Characterization of temperature-sensitive alleles of Schizosaccharomyces pombe septation initiation network components #micropublication #biology #data #caltechlibrary #Spombe #PhenotypeData #GeneticScreens #NewFinding #MaterialsAndReagents micropublication.org/journal…
Our newest CK1 publication is now out in @ScienceAdvances headed by @KinaseQueen ! We built upon our model of CK1 function by investigating the role of the C-terminal tail in substrate specificity. science.org/doi/full/10.1126…
Gould Lab retweeted
The program of the Plant and Microbial Cytoskeleton GRC is online: grc.org/plant-and-microbial-…
Lots of opportunities for short talks!
Re-tweet and submit your abstracts!
#cytoskeleton #actin #microtubules #septins
#yeast #plants #bacteria #archaea #protists
Gould Lab retweeted
Another set of temperature sensitive alleles that didn’t fit into a recent pub. Special thanks to undergraduate student Bita Tavafoghi for her hard work finishing this up!
Generation and characterization of temperature-sensitive alleles encoding GPI anchored proteins Psu1 and Dfg502 in Schizosaccharomyces pombe #micropublication #biology #data #caltechlibrary #Spombe #PhenotypeData #FindingsPreviouslyNotShown micropublication.org/journal…
We made a set of ts alleles for a recent project but some of them didn’t end up fitting into the final paper. We wanted to make sure to publish them though! Special thanks to former undergrad @isaac__howard for all his hard work on this!
Generation and characterization of temperature-sensitive alleles of the glucanosyltransferase Gas1 in Schizosaccharomyces pombe #micropublication #biology #data #caltechlibrary #Spombe #GeneticScreens #NewFinding #MaterialsAndReagents micropublication.org/journal…
Gould Lab retweeted
FEATURED MBoC ASSOCIATE EDITOR: @SophieMartinLab, @unil
How do you believe MBoC can benefit researchers in your area?
MBoC has been a place to publish no-hype, solid research in cell biology & will continue to be thanks to strong community engagement.
molbiolcell.org/
