
DNA Nanotechnology | Super Resolution Microscopy | Single Molecule Localization Microscopy Postdoc @LabTinnefeld
Göttingen
Joined October 2015
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Dive into the captivating realm of 3D multi-target super-resolution microscopy with MIET and DNA-PAINT techniques! This innovative research unveils a new frontier in understanding cellular structures, promising to revolutionize our grasp of biology at the microscopic scale.
📢 Excited to share our new preprint "Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT"! biorxiv.org/content/10.1101/…
#DNAPAINT #MIETPAINT #FLPAINT #SRM #MIET #FLIM @uniGoettingen
A short 🧵👇
Samrat Basak retweeted
🦙🧛♂️ Alpacula brewed up #SMLM treat! No more horror stories of no blinking & black holes⚫️🔬Our single-domain anti-BOOdies 👻 #FluoTags and #SmartSecondaries now glow with self-blinking JF635b✨, delivering frightfully precise and simple #dSTORM imaging 👉bit.ly/4ffIkdB
Samrat Basak retweeted
The #MaxPlanckPostdocProgram offers a guaranteed contract of at least 3 years, targeted mentoring, and career workshops. The call for applications is open now! 🚀 Take advantage of this opportunity and browse the job vacancies. mpg.de/en/max-planck-postdoc…
Samrat Basak retweeted
Excited to share our new work on Brownian DNA Computing!
1/4 📢🥳now online: BROWNIAN DNA COMPUTING - Unlike fuel-driven molecular computing with high-energy barriers, it exploits thermal fluctuations.
Inputs rectify state access, enabling fast, low-energy computation. 📜More in our preprint: biorxiv.org/content/10.1101/…
Samrat Basak retweeted
Brownian DNA Computing biorxiv.org/content/10.1101/…
Samrat Basak retweeted
a bit emotional moment to see this out. Thanks to the team for evolving the idea and its demonstration 😀.
1/4 📢🥳now online: BROWNIAN DNA COMPUTING - Unlike fuel-driven molecular computing with high-energy barriers, it exploits thermal fluctuations.
Inputs rectify state access, enabling fast, low-energy computation. 📜More in our preprint: biorxiv.org/content/10.1101/…
Samrat Basak retweeted
Formal ads are out now for openings in our #CDlab:
careers.tudelft.nl/job/Delft…
careers.tudelft.nl/job/Delft…
careers.tudelft.nl/job/Delft…
careers.tudelft.nl/job/Delft…
careers.tudelft.nl/job/Delft…
So, ambitious talented experimentalists: please apply!
WORK!
My lab currently have 5 (!) open positions for postdocs/PhD students for:
-Nanopore protein sequencing
-Archaeal CDV cell division
-Microfluidics for synthetic cells
-Nuclear Pore Complex
-Origami mimics of peroxisomes
Please apply! ceesdekkerlab.nl/come-join-u…
RT=👍
Proud to see this preprint out!
First time demonstrated Confocal MIET DNA-PAINT and has been a challenging but rewarding journey, and I’m excited about the possibilities it opens for 3D multiplexed nanoscopy in cells.
🚨 New preprint update! 🚨
We introduce Confocal MIET-PAINT — extending our 3D nanoscopy method with:
✨ High multiplexing capacity
✨ Isotropic nanometer-scale resolution
✨ Compatibility with custom & commercial confocal SMLM equipped with FLIM
biorxiv.org/content/10.1101/…
Samrat Basak retweeted
WORK!
My lab currently have 5 (!) open positions for postdocs/PhD students for:
-Nanopore protein sequencing
-Archaeal CDV cell division
-Microfluidics for synthetic cells
-Nuclear Pore Complex
-Origami mimics of peroxisomes
Please apply! ceesdekkerlab.nl/come-join-u…
RT=👍
Excited to share that our project from @LabTinnefeld with @JungmannLab and has been selected for the CeNS Investment Fund! Looking forward to advancing nanoscale imaging and molecular mapping at LMU Munich, and to many more synergies of exciting work ahead!
Shoutout to @heerpa from @JungmannLab to make this happen together!
Samrat Basak retweeted
GAGA zinc finger transcription factor searches chromatin by 1D–3D facilitated diffusion
nature.com/articles/s41594-0…
Samrat Basak retweeted
Great to see this is now out in @NatureNano! Thanks to @leonard_prins for this (yet another) collaborative project...kudos to @erica_delgrosso and Ben Roberts for combining experiment and theory in such a nice way. Thanks also to @EPenocchio for help with the theoretical part!
New paper online:
An information ratchet improves selectivity in molecular recognition under non-equilibrium conditions.
"...mechanism increases selectivity for the correct DNA duplex from 2:1 at equilibrium to 6:1 under energy-dissipating conditions."
nature.com/articles/s41565-0…
Great lab and PI to start with..!
🚨 2 × PhD positions @EPFL @epflSV! Help us push the boundaries of fluorescence microscopy - DNA nanotech, custom optics & spatial omics in Lausanne 🇨🇭. Start Jan 2026. Send CV + motivation + 2 refs → [email protected]
#PhD #Hiring #microscopy #SpatialOmics #DNAPAINT #FLASHPAINT
Samrat Basak retweeted
Fresh out of the oven, although originally very cold😜
Hybridization of molecules via a common photonic mode
| PNAS pnas.org/doi/10.1073/pnas.25…
Samrat Basak retweeted
🎊Fantastic work!!! This pre-print by @LE_Laurent_ @S_LevequeFort et. al introduces Brightness Demixing for simultaneous 3-target imaging using 1 laser🤯
📷 Our #DNAPAINT ready 2ry antibodies & imagers were used for vimentin, clathrin,& tubulin imaging
biorxiv.org/content/10.1101/…
Samrat Basak retweeted
🔬 𝗕𝗲𝗵𝗶𝗻𝗱 𝘁𝗵𝗲 𝗕𝗶𝗻𝗱𝗲𝗿𝘀: 𝗠𝗲𝗲𝘁 𝗝ü𝗿𝗴𝗲𝗻 𝗦𝗰𝗵𝗺𝗶𝗲𝗱🔬
Today, we’re spotlighting Dr. Jürgen Schmied, CEO and co-founder of Massive Photonics, whose leadership is central to our goal of enabling scientists solve critical research questions using DNA-PAINT technologies.
With a background in Biophysics, Microscopy, and DNA nanotechnology combined with a sharp sense for innovation and business, Jürgen brings both visionary leadership and technical insights to the table.
Jürgen earned his PhD in Physics from the Technische Universität Braunschweig, where he developed imaging standards for super-resolution microscopy using fluorescently labeled DNA origami. In 2014, he co-founded @GATTAquant, known for its high-precision fluorescent nanorulers and standards for microscope characterization. In 2019, he co-founded Massive Photonics to make DNA-PAINT tools widely accessible to the scientific community.
Today, Jürgen guides our strategy, direction, and operations, ensuring researchers have powerful, precise, and easy-to-use tools they need to uncover biology at the nanoscale.
🔜 Stay tuned as we take you #BehindTheBinders - one moment at a time.
#SMLM #DNAPAINT #Microscopy #DNAorigami #LifeScience #SuperResolution
Samrat Basak retweeted
🔬🧬 New in @NatureComms: Nanoscale 3D DNA tracing in non‑denatured cells maps the #3Dgenome at nm‑resolution and reveals Cohesin‑dependent dynamic loops! 🚀 #OpenAccess
nature.com/articles/s41467-0…
EllenbergLab @JungmannLab #Genomics #SuperResolution
Samrat Basak retweeted
🎉 Großer Erfolg in der Exzellenzstrategie für die #LMU: Alle sieben beantragten Exzellenzcluster haben sich im Begutachtungsverfahren durchgesetzt und werden ab 2026 für sieben Jahre gefördert! Ein herausragendes Ergebnis! 🎉lmu.de/de/newsroom/newsueber…
Super news...! Many congratulations
Big news: I’m joining @EPFL_en as Tenure-Track Assistant Professor of Life Science Engineering!
Can’t wait to push super-resolution microscopy & spatial omics even further and build new collaborations in Lausanne. 🚀
#EPFL #SuperResolution #Microscopy #SpatialOmics #DNAPAINT
Samrat Basak retweeted
🔬 SPAOM is a 3-day dive into the latest in optical microscopy & image analysis, with applications from 🧠 neuroscience to 🧬 cancer biology.
Bringing together Iberian & European scientists to connect, share & innovate 🤝🌍
#microscopy #imageanalysis #lifesciences #SPAOM


























