Exploring and expanding non-conventional druggable space. Postdoc in the @disney_lab (Scripps Research), @StephanHacker2 lab alumnus (TU Munich, Uni Leiden)
Jupiter, FL, USA
Joined January 2020
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Excited and proud to be recognized for my PhD work with this award! Thank you for this honor and to everyone involved in my projects, first and foremost my advisor and mentor @StephanHacker2. And congratulations to my fellow award winners!
#fimc2022 @GDCh_aktuell
Congratulations to the winners of the GDCh Division of Medicinal Chemistry's 2022 PhD Awards: Dr. Patrick Zanon @patrick_zanon, Dr. Johannes Morstein @mo_hannes, and Dr. Verena Kunig!
#FiMC2022 #medchem #pharma #drugdiscovery #euromedchemtalents #medchemtalents @GDCh_aktuell
Patrick Zanon retweeted
Congratulations Jess sam and team on study to manipulate rna quality control in neurons/mice to eliminate disease RNAs - RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome | PNAS pnas.org/doi/10.1073/pnas.22…
Patrick Zanon retweeted
Congrats to Sam and Team - DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC) pubs.acs.org/doi/10.1021/jac…
Patrick Zanon retweeted
Just found out that our isotopically labeled desthiobiotin azide (isoDTB) tags (doi.org/10.1002/anie.2019120…) for residue-specific chemoproteomics using a variant of isoTOP-ABPP are now commercially available. clickchemistrytools.com/prod…
Patrick Zanon retweeted
Congratulations to Hamish on new paper - Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA pubs.acs.org/doi/10.1021/jac…
Patrick Zanon retweeted
@AntheJanssen and I have a fully-funded, 4-year PhD position for a researcher interested in computational and chemical biology approaches to develop new antibiotics. Join us to do great science in beautiful Leiden @UniLeiden @LeidenScienceEN @LeidenScience universiteitleiden.nl/en/vac…
Patrick Zanon retweeted
Join us for the 2nd Munich-Leiden Virtual @ChemBioTalks! A very exciting lineup of speakers and the first time that we will also include flash talks by PhD students and postdocs. If you want to actively participate in that way, make sure to look at the abstract challenge.
We are excited to share the full program of the 2nd Munich-Leiden Virtual ChemBio Talks on September 27th, 2022 with talks by @ChemicalBiology, Herbert Waldmann, Zhengqiu Li, @kimbonger, @Adam_S_Nelson, @RentmeisterLab and @hargrovelab. Free registration: events.bizzabo.com/402968/ho…
Patrick Zanon retweeted
Today in @eLife we reveal the mechanism of action of a large family of highly cytotoxic lipids and show how it can be exploited. Opens many applications, since novel molecules with selective cytotoxic effects can be designed from this elifesciences.org/articles/7…
Patrick Zanon retweeted
Excited that this great study led by @SebBritton1 is out @eLife. Very happy that @patrick_zanon and I could make a contribution using residue-specific proteomics. Check it out to learn how SDRs oxidize alkynylcarbinols into protein-reactive electrophiles. doi.org/10.7554/eLife.73913
Patrick Zanon retweeted
Very excited that our former group member @patrick_zanon received one of the GDCh Division of Medicinal Chemistry's 2022 PhD Awards for his PhD thesis at the Frontiers in Medicinal Chemistry #fimc2022 @GDCh_aktuell. Congratulations, Patrick! #proudPI
Patrick Zanon retweeted
I am glad to share our new optimised chemical proteomic workflow for low protein input in 96-well plate, we call it SP2E. Easy, robust and fast. Try it out! We used it for analysis of AMPylation and O-GlcNAcylation. Thanks to Tobias and all coauthors. biorxiv.org/content/10.1101/…
Patrick Zanon retweeted
Our group has a few postdoc positions open on rna chemical biology esp degraders. If you have base skills in organic synthesis, structural biology/biophysics/biochemistry, or informatics and are interested pls email me at Disney@scripps.edu
Patrick Zanon retweeted
I am still looking for talented PhD candidates!
We have funding and exciting projects in the field of early drug discovery! pomplunlab.com/open-position…
Looking for background in (and love for) organic synthesis!
@LeidenScienceEN #chemjobs #medchem #chembio
Patrick Zanon retweeted
Congratulations to @ListLaboratory and @MacMillan_Lab on the @NobelPrize for their amazing work on asymmetric organocatalysis!
Here's a throwback to about two years ago, when @ben_list gave a talk at our CheMUC Campus Event together with @DaumannL, @DavidBKonrad and Golo Storch!
Happy to have contributed to this cool story!
A chemical biology story: in this preprint we report the discovery of the mechanism of action of a large family of cytotoxic lipids, turning out to be prodrugs bioactivated into protein reactive-species by the human Short-Chain Dehydrogenase (SDR) HSD17B11 biorxiv.org/content/10.1101/…
My defence on Friday was the grand finale to my time in Munich. I am very grateful for all friends, family, colleagues and collaborators who accompanied me during this almost full decade!
Very excited that @patrick_zanon is now officially the first Ph.D. student to finish his Ph.D. in our group. After a very successful Ph.D. project, he also excelled in his oral thesis defense and passed with distinction. Congratulations, Patrick! #proudPI
In particular I want to thank @StephanHacker2 and @SieberLab for making my PhD an extremely positive experience and my examination committee Matthias Feige, @CathleenZeymer and @klanglab.
Patrick Zanon retweeted
Interested in integrating #FragPipe in your Chemical Proteomics workflow? Listed to this webinar by our terrific collaborators, presented by Patrick Zanon from @StephanHacker2 lab. One area where we are putting a lot of effort, new collaborations welcomed! youtube.com/watch?v=qEDDCLsc…
Patrick Zanon retweeted
In case you missed the talk by @patrick_zanon at the @LPDGproteomics seminar, check out the recording on @YouTube #proudPI: youtube.com/watch?v=qEDDCLsc…. Learn about our chemoproteomic experiments to study electrophile reactivity using a #FragPipe workflow developed by @nesvilab.
@patrick_zanon gave an excellent talk at the @LPDGproteomics seminar presenting our recent @ChemRxiv preprint on the proteome-wide reactivity of diverse electrophiles. #proudPI (1/3) doi.org/10.26434/chemrxiv.14…
Excited to be part of this event on Friday! Register and join the conversation on chemoproteomics here: londonproteomics.co.uk/
Our next webinar, this time sponsored by MSWil, is this Friday 18th June, 2pm BST and will be focused on chemical proteomics. We will have two exciting speakers @theWittySquare, @patrick_zanon and guest chair @MBantscheff
