🚀 our new paper is out in Nature.
Huge congrats to everyone for their creativity, persistence and brilliant teamwork! 🥳🙌
It all started many years ago with a failed experiment...
👉 full 🧵 on Bluesky 🦋
Nature research paper: Hijacking a bacterial ABC transporter for genetic code expansion
go.nature.com/3J2iTSE
🔥 We have two open full prof positions at our institute (LOC) at @ETH_DCHAB @ETH_en
1. Synthetic Organic Chemistry
2. (Bio)Analytical Chemistry
Apply until Nov 15 and be our colleague!
ethz.ch/en/the-eth-zurich/wo…
Come be our colleague 👇. Two positions (synthetic organic and (bio)analytical) open at our institute (LOC). Amazing students and staff, colleagues, facilities, location, and long-term funding perspectives. What are you waiting for? Apply today 😀. @ETH_DCHAB #chemjobs
Happy that this is finally online!
Genetic code expansion approaches to decipher the ubiquitin code @ACSChemRev
Many congratulations to Vera, Max and Marco!
@VeraWanka @MaxFottner @MarkoCigler 🥂🎉🥳
pubs.acs.org/doi/10.1021/acs…
On our way to #GCE2024 in Corvallis @GCEcenter, starting with a small Chinlab reunion in San Francisco. So great to see you all again! Inja, Wolfgang, Tao, Sebastian…like in old times 🤩😊
Many thanks Daniela @DankovaDaniela and @ChristianAOlsen for writing this comprehensive News and Views!! We really appreciate it 😊!!
I'm happy to share our News & Views article featured in @NatureChemistry, highlighting the excellent work on site-specific incorporation of glutarylated and succinylated lysine residues into multidomain proteins via genetic code expansion by @klanglab!
nature.com/articles/s41557-0…
We have a new Dr 🎓👨🎓in the @klanglab! Many congrats Toni, Dr. Murnauer, we are very proud of you! 👏🏻😊 and many thanks to co-examinator @StephanHacker2 who came all the way from Leiden and to @mvkovalenko for chairing the committee! 👨🔬⚗️🐘 #tetrazines #DMBO #bioorthogonal
It was great to be at @ETH Zurich for the PhD defense of Anton Murnauer of the @klanglab. He performed a lot of exciting science on genetic code expansion and bioorthogonal chemistry. Congratulations, Dr. Murnauer, and thank you, @klanglab, for inviting me doi.org/10.1002/anie.2019082…
Very excited to co-organize GCE2024 with @AChemSynBio and @Mehl_lab at @GCEcenter!
Come to Corvallis, Oregon to hear about the newest in genetic code expansion! We have a stellar speaker lineup from academia and industry!👇
Retweet and register!
gceconferences.org/
🚨🚨All genetic code expansion enthusiasts, don’t miss the GCE 2024 conference this summer (gceconferences.org/)! Fantastic speakers both from academia and industry. Please retweet! @klanglab @Mehl_lab
Genetically encoding negatively charged lysine PTMs succinylation/glutarylation and studying their funcional roles! Great team effort by first authors @ML_Jokisch and @Maria_Weyh! Congrats @Maria_Weyh @ML_Jokisch @MaxFottner and Anh! 🥳🤩🙌👨🔬🧑🔬 @klanglab
nature.com/articles/s41557-0…
SucK and GluK can be encoded co-translationally as temporarily masked thioester derivatives. They regulate enzymatic activity of metabolic enzymes (GAPDH), protein-protein interactions (Ub signaling) and DNA-protein intereactions (DNA clamp loading)
#PTMs, #GCE @NatureChemistry
Straight to the face 👊
Nice collaboration with @houk1000 and @Click_Chemist! Small cycloalkane fusions enhance the cycloaddition reactivity of dibenzocyclooctynes (especially towards tetrazines 🩷)
Many congrats to Toni and Dennis! 🧪💻🧑🔬🧑💻
#bioorthogonal
doi.org/10.1039/D3SC05789E
Very much looking forward to this!! 🤩 Exciting chembio in great company in one of my favourite european cities (with some of the best restaurants 😋), what is not to like! Many thanks for inviting and organizing @LabPless @stromgaardlab @ChristianAOlsen and everyone involved.
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This is pretty cool! 🤩👌
Another exciting new tool to engineer biology from the Jason Chin Lab >>> Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli | Science science.org/doi/10.1126/scie…
Looking forward to this one!
Application deadline extended to Nov. 12!
Discuss the development of chemistry-based tools to unravel signaling networks in cells + tissues #chembio
Registration + hotel + meals covered
Learn more + apply @ bit.ly/CHM2024
@HHMINEWS @BiochemSoc @nchembio @HHMIJanelia
Kathrin Lang retweeted
👩🔬👨🔬 Calling all Prof. & Independent Senior Scientists in 🇨🇭 chemical biology! 🧪🔬 Join 🇨🇭SNE chembio community sne-chembio.ch& become a member:
👉 bit.ly/492pAw5 sne-chembio.ch
👇exclusive benefits 😀
🙏 share the info!
#ChemBio #Together
very much looking forward to having you here, Michael!
safe travels!
Really excited to be visiting ETH Zürich @ETH_DCHAB next Monday to meet new people and give a talk on our latest work on controllable nucleic acids 😊🤩🧬
Thanks to @klanglab for the invite!
We have a new doctor in the @klanglab! Well done to Kristina - Dr. Krauskopf - who successfully defended her thesis!🎓🥳👏 Many thanks to @SieberLab and Hubert Gasteiger for being on the committee at TUM! Very sorry for only being present via Zoom and missing the party fun 🤒🦠🙄
Oh yes!! Waiting and rooting for this for years! DNA synthesis/Marvin Caruthers...there would be no molecular biology without! Maybe 2023 is the year! 💪 #chemnobel
It's #chemnobel season, so your reminder that DNA synthesis/Marvin Caruthers needs to win!
Without DNA synthesis there is NO *PCR*, *sequencing*, *cloning*, *CRISPR*, *siRNA*, *synthetic biology*, *mRNA vaccines*, *nucleic acid therapeutics*, *Nanotech*
What more am I missing?
Really enjoying my walks to and from work in this gorgeous september weather @ETH_DCHAB ☀️🏔️🐮🐈🐑🇨🇭
