Assistant Prof at University of Illinois Chicago.
Joined January 2022
- Tweets41
- Following112
- Followers73
- Likes300
Preetish Murthy retweeted
Excited to share this work, now out in @NatureGenet . There is no cure for #COPD. To tackle this challenge, we performed nuclear sequencing, spatial transcriptomic, and proteomic analysis of lung tissue from 141 subjects to better understand this disease. nature.com/articles/s41588-0…
Preetish Murthy retweeted
Excited to share our latest preprint:
A spatially-resolved blueprint of the developing human lung reveals a WNT-driven niche for basal stem cells.
biorxiv.org/content/10.1101/…
Led by a talented team: @PeggyPHsu, Tristan Frum and Ansley Conchola - and with many other contributors!
Preetish Murthy retweeted
I'm incredibly excited to share our most recent work: "Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis"
doi.org/10.1101/2023.12.15.5…
Preetish Murthy retweeted
Excited to share new work from our group led by terrific @VUMC_MedPSTP @VUMCLung fellow Scott McCall
Hypoxia-inducible factor-2 (HIF2) regulates alveolar regeneration after repetitive injury biorxiv.org/content/10.1101/…
Preetish Murthy retweeted
Today our Human Lung Cell Atlas (HLCA) paper came out in Nature Medicine nature.com/articles/s41591-0…! The HLCA includes 2.4M cells from 486 individuals and 49 datasets. Check out this tweetorial to learn more about how we built it, and how you can use it (1/21)
Preetish Murthy retweeted
A new manuscript from the lab led by MSTP student, Ansley Conchola, with @tristanfrum @PeggyPHsu and others...
Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung
pnas.org/doi/10.1073/pnas.22…
Preetish Murthy retweeted
Incredibly excited to share out latest work using single cell RNA sequencing to identify eQTLs across 38 cell types in primary human lung tissue. biorxiv.org/content/10.1101/… 1/n
Preetish Murthy retweeted
Spatial epigenome–transcriptome co-sequencing🤩🤩🤩Beyond excited to see it out today @Nature! Enjoyable collaboration between my lab @YaleBME @YaleSEAS @YaleMed and @GoCasteloBranco of @karolinskainst. The most informative tool for spatial multi-omics!!
nature.com/articles/s41586-0…
Preetish Murthy retweeted
Hot off the @biorxivpreprint press: check out our latest work, making the world's flattest cells: "Generation of human alveolar epithelial type I cells from pluripotent stem cells" @CReM_Boston @BUPulmonary biorxiv.org/content/10.1101/…
Preetish Murthy retweeted
Big day in the lab! Always wanted to study how dormant cancer cells interact with #brain cells. Thanks to the support of @TheMarkFdn we'll do it! We are recruiting! Neuroscientist, computational scientist interested in vivo #imaging, #spatialtranscriptomic, #dormancy DM/email me!
Congratulations Jose Javier Bravo-Cordero @BravoCorderoLab @TischCancer @IcahnMountSinai bit.ly/3QQZ5Rn
Preetish Murthy retweeted
[1/20] Modeling disease directly in human tissue slice cultures transforms mechanistic studies as well as drug development and translation. A thread on our new work @biorxivpreprint.
bit.ly/3H9LTnr
Two amazing first authors: @niklasjlang @schniering_j
@HelmholtzMunich
Preetish Murthy retweeted
Delighted to share our pre-print on "Early human lung immune cell development and its role in epithelial cell fate" biorxiv.org/cgi/content/shor… in collaboration with Sarah Teichmann & Kerstin Meyer @teichlab @sangerinstitute. Thanks especially to the amazing co-first authors...(1/2)
Preetish Murthy retweeted
Brilliant to see this come out. Especially congratulations to the co first authors @KyungtaeL @PengHeCam @sundakao
The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer.
ebi.ac.uk/about/news/researc…
Preetish Murthy retweeted
Excited to share my first 1st-author pub from @Tatalab_Duke!
A quick 🧵:
Have you ever seen an epithelial cell with more than one apical domain? Here, we present evidence for multi-apical polarity of alveolar stem cells (AT2s) @iScience_CP
bit.ly/3Lt4lIB (1/6)
Preetish Murthy retweeted
Ever wonder how Transcription Factors work as a team?
Thrilled to share our latest work on TF cooperativity now online @MolecularCell
“Stripe” TFs provide accessibility to regulatory DNA in mammalian genomes
cell.com/molecular-cell/full…
What are stripe TFs, you ask?
🧵👇
1/13
Preetish Murthy retweeted
New preprint by @UMichCMB #UMichMSTP student Ansley Conchola, with lab mates @tristanfrum @PeggyPHsu and others. In collab with @klpreetish @Tatalab_Duke.
Distinct airway progenitor cells drive epithelial heterogeneity in the developing human lung.
doi.org/10.1101/2022.06.13.4…
Distinct airway progenitor cells drive epithelial heterogeneity in the developing human lung biorxiv.org/cgi/content/shor… #bioRxiv
Preetish Murthy retweeted
🚨📣💥 the @SweetCorderoLab is hiring a #postdoc interested in studying sarcoma metastasis with single cell omics and lineage tracing in unique patient-derived models and GEMs. Highly collaborative environment @ UCSF… join us!
Preetish Murthy retweeted
New from the lab: @robertblassberg & co on how the levels of SOX2 influence where WNT signaling effectors bind to chromatin
This determines the WNT response & explains how one signal elicits different responses in different cell types #OA
nature.com/articles/s41556-0…
Preetish Murthy retweeted
During our second session, Ying Zhang, @EManiou @_Bethan_Clark and @klpreetish will take the stage to talk about brain sparing, lung progenitors, pigmentation patterns and biomechanics 🧠🫁🐠👩🔧
Preetish Murthy retweeted
Tumors spread to lymph nodes before they metastasize to distant tissues, but for over a century scientists have debated whether this matters. It does. Check out our paper online now @CellCellPress @CellPressNews
cell.com/cell/fulltext/S0092…
1/15
