The Austin Allegro was ridiculed.
The solution? Add chrome, walnut and luxury. Enter the Vanden Plas.
Genuine improvements. Same underlying car, sprinkled with glitter.
Medicine can face the same dilemma.
How do we recognise when it's time to stop refining and start rethinking?
Ian Lake retweeted
This was Monday's note - the second of two parts on the ZOE 30 plants product.
Many of my lovely subscribers asked if it could go on open view so they could share it. So it's here...
zoeharcombe.com/2026/10/zoe-…
Ian Lake retweeted
“Not enough evidence.” “Unsustainable.” “You need carbs for energy.”
Still on the same track 😞
🗣️ Dr Ian Lake, a GP who has type 1 diabetes, shares this year’s Delphi consensus guideline on therapeutic carbohydrate reduction: journalofmetabolichealth.org…. Straight and usable in clinic.
Real food: protein, fats from whole foods, and vegetables. The panel sees it as sufficient and safe in obesity, metabolic syndrome and type 2 diabetes. Adaptation is short, and people can stick with it.
🥗 @DietDoctor says the same — their guide for dietitians, updated in August: dietdoctor.com/low-carb/for-… — and quotes the ADA: cutting carbs has the most evidence for improving blood glucose. The brain does not need dietary carbs; gluconeogenesis and ketones cover it.
📚 @NutritionNetwrk backs it too: their November research update summarises systematic reviews with type 2 diabetes remission of up to 62% at one year: nutrition-network.org/resear…
Things are moving !! 🤟 💪
✍️PS: the same Dr Ian Lake sat down with Nutrition Network for a live on a lower-carb approach to type 1 diabetes — paediatric glucose swings, Bernstein’s law of small numbers, night hypos, and the usual myths about growth. 🔗 xitter.cf/NutritionNetwrk/status… – at Valparaíso, Chile
"Not enough evidence"
"Unsustainable"
"You need carbs for energy"
Still repeating this?
The new 2026 clinical guideline on therapeutic carbohydrate reduction in metabolic disease. Highly readable, Highly practical.
Things are moving on.
tinyurl.com/5emkm97y
#diabetesuk
Ian Lake retweeted
Been on low carb for 11 years now.
If i waited for "evidence based approvals" then i would have been on multiple meds by now.
"Not enough evidence"
"Unsustainable"
"You need carbs for energy"
Still repeating this?
The new 2026 clinical guideline on therapeutic carbohydrate reduction in metabolic disease. Highly readable, Highly practical.
Things are moving on.
tinyurl.com/5emkm97y
#diabetesuk
"Not enough evidence"
"Unsustainable"
"You need carbs for energy"
Still repeating this?
The new 2026 clinical guideline on therapeutic carbohydrate reduction in metabolic disease. Highly readable, Highly practical.
Things are moving on.
tinyurl.com/5emkm97y
#diabetesuk
Same breakfast buffet. Two plates. Two people convinced theirs is the healthiest.
She knew nothing about my metabolism. I knew nothing about hers.
Food doesn't meet a guideline. It meets a metabolism.
Perhaps the question isn't “Which breakfast is healthy?”
Healthy for whom?
Into wellness or Type 1 diabetes (or both?)
Do you time your meals to suit your metabolism or the daily routine?
It can be difficult but having information helps decisions.
Easy when you know .
What can 21 days of continuous glucose and ketone data, recorded during a 1,000-mile cycling journey, reveal about managing type 1 diabetes on a ketogenic diet?
@idlake is a UK-based primary care physician who has lived with type 1 diabetes for more than 30 years. After two decades of conventional high-carbohydrate management, he adopted a very low-carbohydrate, ketogenic approach and began examining insulin not simply as a glucose-lowering medication, but as a metabolic hormone whose requirements are influenced by nutrition, exercise, sleep, circadian rhythm, hydration, and stress. His new book, Shifting Gears, documents the ride and the lessons he took from it.
Dr. Lake treated the journey as a 21-day personal experiment, wearing continuous glucose and ketone monitors while consuming roughly 20 grams of carbohydrate per day. In this conversation with @DominicDAgosti2, he shares what his data showed: an average ketone level near 1.2 mmol/L, daily insulin requirements declining from the mid-20s of units to around 16, and an episode in which glucose and ketones rose together after he had taken too little insulin.
Dr. Lake describes how, in his case, one unit of insulin brought his ketones from approximately 3.0 to 0.9 mmol/L within about 20 minutes. He and Dr. D’Agostino use the experience to explore the distinction between nutritional ketosis and diabetic ketoacidosis, the essential role of adequate insulin, and why ketone readings must always be interpreted alongside glucose levels and clinical context.
They also discuss insulin sensitivity during prolonged exercise, the practical challenges of adjusting insulin during endurance activity, and research suggesting that fat-adapted athletes may sustain high rates of fat oxidation at relatively high exercise intensities.
Questions Answered in This Episode
• What did 21 days of continuous glucose and ketone monitoring reveal during a ketogenic, 1,000-mile cycling journey?
• How did prolonged endurance exercise affect Dr. Lake’s daily insulin requirements?
• How is nutritional ketosis different from diabetic ketoacidosis, and what role does insufficient insulin play in DKA risk?
• What did Dr. Lake observe when his glucose and ketones began rising at the same time?
• How might fat adaptation influence fuel use and endurance performance?
• What are the practical limitations of continuous glucose and ketone monitoring for real-time insulin decisions?
This conversation offers a rare look at 21 consecutive days of glucose, ketone, insulin, nutrition, and exercise data, while also emphasizing that Dr. Lake’s experience is an individual case, not a substitute for personalized medical supervision.
Ian Lake retweeted
How often do you set aside a few minutes to evaluate your priorities, challenges, & progress?
Ian Lake retweeted
John Rollo, a Scottish physician in the British Army in the late 1700s, wrote “An Account of Two Cases of the Diabetes Mellitus”, which provided a detailed clinical report and was among the first to propose a low-carb, high protein dietary management approach.
Thanks to @BiggestComeback for your interview about very low carb in type 1 diabetes and why it is important to manage insulin as tightly as we try to manage glucose. Swilling it around as if it is harmless is not going to end well.
Replying to @GregoryMaysMD
I had the opportunity to interview @idlake for this article for @lowcarbusa
lowcarbusa.org/dr-ian-lake-w…
Ian Lake retweeted
Replying to @GregoryMaysMD
I had the opportunity to interview @idlake for this article for @lowcarbusa
lowcarbusa.org/dr-ian-lake-w…
Ian Lake retweeted
After the brilliant conference at the weekend where we celebrated our 10th anniversary I now have even more reading to do!! @PHCukorg @SteveBennettMhP @drlouisenewson @idlake @RichardJJohns11
Thank you #NHS. Just had my annual Type 1 review. It was quick but the wonderful nurse was super efficient and covered everything including bloodwork follow up and retinal screening. And the room temperature didn't drop when I mentioned the keto word either. All good here.
Something's not right.
In many fields of medicine, the importance of insulin is recognised as a contributor to the disease.
Yet in the very speciality invented to study it, diabetology, insulin is overlooked in the pursuit of 'control the sugar at all costs'.
Confusing
Ian Lake retweeted
If the doctors who first used insulin visited a diabetes clinic today they would have no trouble updating. The measure of control is still glucose, insulin is still injected into the skin. ‘We’ve always done it like that’
What would shock them though would be the diet. Regressive
Depends what you mean by nutrition training. 40 hours of old style macro and metabolic teaching would be a disaster if it is the same stuff I was taught all those years ago. Thank goodness it was only a few hours. But if it is OUR type of nutrition training it will be great.
Replying to @SecKennedy @EDSecMcMahon
The average medical student currently receives less than 20 hours of nutrition training in four years, even though diet-related metabolic dysfunction now accounts for nearly 70% of all global deaths.
We are essentially asking doctors to fight a wildfire with a water pistol while the industrial food system pours gasoline on the flames.
our modern food supply was engineered to keep us sick, check the deep-dive exposé on my pinned post.

























