Associate Professor @CGM_MGH @HarvardMed | Statistical Genetics | Brain Imaging | Precision Medicine
Boston, MA
Joined March 2018
- Tweets97
- Following528
- Followers486
- Likes974
Tian Ge retweeted
Our multi-ancestry GWAS of EXTernalizing conditions (ADHD, substance use...) in ~4M people reveals neurodevelopmental risk, drug-repurposing targets, and yields one of the strongest psychiatric polygenic indices yet! 🧬🎉 doi.org/10.64898/2026.02.09.…
Tian Ge retweeted
Excited to share that our new paper in Nature Genetics! Huge thanks to @hailianghuang and @getian107 for supervising this project and to @broadinstitute, @CGM_MGH and @PGCgenetics for supporting the research. rdcu.be/dR0sF
Pleased to share a new preprint led by the amazing @jd_tubbs, in which we developed a real-time PRS construction algorithm that can dynamically update SNP weights to integrate streaming data. Check out Justin's brief thread for more details👇
Introducing real-time PRS-CS! Excited to share our new preprint with @getian107. Optimized for healthcare settings, rtPRS-CS ensures patients receive the most up-to-date genetic risk prediction by dynamically updating PRS weights using streaming data. 1/7
medrxiv.org/content/10.1101/…
Tian Ge retweeted
Exciting news! Our latest study has been published in @NatureComms: nature.com/articles/s41467-0…
Congrats and huge thanks to @ChiayenChen, @heikorunz, and all our other co-authors, @getian107, @ToddLencz, @maxzylam, @jimmyzliu, @eatsai for their exceptional contributions!
Tian Ge retweeted
Thrilled to announce our latest study published in @CellGenomics !
cell.com/cell-genomics/fullt…
Big shoutout to our amazing collaborators @ChiayenChen @getian107 @hailianghuang @AnnejaneF and many others!
#GWAS #TaiwanBiobank🧬
Tian Ge retweeted
Check out our speakers and topics! Don’t miss this virtual conference. Registration is free for students and trainees and CME/CE credits available
We are just one month away from the 3rd Annual Conference on Precision Psychiatry: Innovation to Implementation! Register today to reserve your spot.
Register at mghcme.org/Precision2023
Check out the conference agenda and more info. at massgeneral.org/psychiatry/r…
#innovation #ai
Tian Ge retweeted
Principles and methods for transferring polygenic risk scores across global populations go.nature.com/3PbbGQ8 #Review
Many thanks to @Linda_Kachuri and @johnwitte for co-leading the review, and all the contributions, discussions and support from @nilanjan10c, @JibrilHirbo, Dan Schaid, Iman Martin, @iftikhar_kullo, @EimearEKenny, @bpasaniuc and the PRIMED Consortium @PRSdiversity!
Our review on the principles and methods for transferring PRS across populations is out today @NatureRevGenet: go.nature.com/3PbbGQ8
Tian Ge retweeted
Now published in @NatureGenet: Our exome study on proxy measures of cognitive function, revealing rare, yet large effect genetic contributions. 🙏to all participants & collaborators for their scrutiny & some truly insightful findings rdcu.be/dcZRe
New preprint! We studied how rare protein-coding variants impact cognitive function & linked diseases in @uk_biobank. We identified 8 large-effect cog fx genes, dosage-sensitivity for KDM5B, additivity of rare variant and polygenic risk & more (1/12) medrxiv.org/content/10.1101/…
Tian Ge retweeted
New work led by @EpiHeather on an under-appreciated problem:
How selection bias may be warping effect estimates of polygenic risk scores.
With @tthaweethai @AnnejaneF @yihansheu Beth Karlson @getian107 @GENES_PK
pubmed.ncbi.nlm.nih.gov/3722…
Tian Ge retweeted
We have open summer co-op positions at the Human Genetics group at Biogen (Jun. to Dec. 2023). Join us for some exciting scientific projects and learning experience! Please reach out if you're interested in this opportunity.
jobs.smartrecruiters.com/Bio…