@YenFengLin

Assistant Investigator attending physician @ NHRI Taiwan

 Taiwan
Joined July 2017
  • Tweets15
  • Following81
  • Followers41
1️⃣ Integrating multi-polygenic scores for antidepressant outcomes Multi-polygenic scores (for insomnia, pain, inflammation) predicted poorer SSRI response in East Asian patients - a step toward personalized antidepressant treatment. nature.com/articles/s41386-0…

Integrating multi-polygenic scores for enhanced prediction of antidepressant treatment outcomes in...

Neuropsychopharmacology - Integrating multi-polygenic scores for enhanced prediction of antidepressant treatment outcomes in an East Asian population

nature.com
1
1
1
55
Excited to share our paper on the methodology of MR‐based causal mediation analysis in Statistics in Medicine! Many thanks to Shu-Chin Lin, @ChiayenChen, @getian107, and ShengHsuan Lin. bit.ly/4aWycFI #MendelianRandomization #MediationAnalysis

Causal Mediation Analysis: A Summary‐Data Mendelian Randomization Approach

Summary-data Mendelian randomization (MR), a widely used approach in causal inference, has recently attracted attention for improving causal mediation analysis. Two existing methods corresponding to...

onlinelibrary.wiley.com
2
75
Yen-Feng Lin retweeted
Kai Yuan@KaiYuan199026 Aug 2024
Excited to share that our new paper in Nature Genetics! Huge thanks to @hailianghuang and @getian107 for supervising this project and to @broadinstitute, @CGM_MGH and @PGCgenetics for supporting the research. rdcu.be/dR0sF
2
17
39
7,711
Yen-Feng Lin retweeted
Justin Tubbs@jd_tubbs15 Jul 2024
Introducing real-time PRS-CS! Excited to share our new preprint with @getian107. Optimized for healthcare settings, rtPRS-CS ensures patients receive the most up-to-date genetic risk prediction by dynamically updating PRS weights using streaming data. 1/7 medrxiv.org/content/10.1101/…

Real-time dynamic polygenic prediction for streaming data

Polygenic risk scores (PRSs) are promising tools for advancing precision medicine. However, existing PRS construction methods rely on static summary statistics derived from genome-wide association...

medrxiv.org
2
14
1
45
6,635
Do you calculate #polygenic scores? Is it tedious and time-consuming? Try GenoPred! Easily installed, reproducible analysis, single command line. Choice of analysis methods, diverse ancestries.
Institute of Psychiatry, Psychology & Neuroscience@KingsIoPPN4 Jun 2024
Dr @ollie_pain & Prof @cathrynlewis have launched GenoPred - a tool that allows researchers to easily calculate #polygenic scores to uncover individuals' genetic risk for certain health-related outcomes 🧬 🔗 👉buff.ly/4c1hjJu
1
35
2
107
11,762
Taiwan Biobank: A rich biomedical research database of the Taiwanese population Top cited paper from @CellGenomics - 17 citations hubs.ly/Q02m-NVf0 @AnnejaneF @YenFengLin
1
8
33
5,437
Thrilled to announce our latest study published in @CellGenomics ! cell.com/cell-genomics/fullt… Big shoutout to our amazing collaborators @ChiayenChen @getian107 @hailianghuang @AnnejaneF and many others! #GWAS #TaiwanBiobank🧬

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for...

Chen, Chen, Feng, Yu, Lin, et al. reported findings from genome-wide analysis in 102,900 Taiwan Biobank (TWB) participants across 36 human quantitative traits. A total of 1,986 significant loci were...

cell.com
11
2
30
5,453
Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits dlvr.it/SywCCn
4
7
1,379
Yen-Feng Lin retweeted
Loïc Yengo@LoicYengo18 Sep 2023
Hi everyone, Our paper about boosting the power of GWAS using polygenic scores (PGS) is just out in @NatureGenet. Please check it out here: nature.com/articles/s41588-0…
3
48
3
159
22,028
Our latest preprint: a novel cross-ancestry fine-mapping method with much improved power and calibration. A collaboration with @kaiyuan1990 @RyanLongchamps @AFPopgen @getian107 @ChiayenChen @YenFengLin @bmneale @dalygene @PGCgenetics among others! medrxiv.org/content/10.1101/…

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying...

Genome-wide association studies (GWAS) of human complex traits or diseases often implicate genetic loci that span hundreds or thousands of genetic variants, many of which have similar statistical...

medrxiv.org
13
1
55
6,048
“Taiwan Biobank: A rich biomedical research database of the Taiwanese population" @AnnejaneF @YenFengLin cell.com/cell-genomics/fullt…

Taiwan Biobank: A rich biomedical research database of the Taiwanese population

Feng. et al. describe an impressive biomedical resource in Taiwan that measures a wide range of characteristics in >150,000 individuals along with their genetic makeup. This resource enables large-...

cell.com
3
4
Excited to see this paper online. Great collaboration with @getian107 @Yunfeng_Ruan @YenFengLin @ChiayenChen @maxzylam @genetisaur Shengying Qin and many others!
Nature Genetics@NatureGenet5 May 2022
🔥 HOT OFF THE PRESS @NatureGenet 📰 Improving polygenic prediction in ancestrally diverse populations 👩🏻‍🤝‍👨🏾 Shengying Qin, Hailiang Huang, Tian Ge, and colleagues 👇🏾 go.nature.com/3vO0Q9p
2
16
2
36
A large-scale genomics resource of East Asian ancestry made available by Taiwan Biobank. A joint project with @ChiayenChen @DrYenFengLin @getian107 @AnnejaneF @dalygene and many others!
medRxiv@medrxivpreprint15 Apr 2021
Analysis across Taiwan Biobank, Biobank Japan and UK Biobank identifies hundreds of novel loci for 36 quantitative traits medrxiv.org/cgi/content/shor… #medRxiv
1
18
3
59
Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms
Alzheimer's & Dementia Journals@alzdemjournals18 Sep 2018
Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms dlvr.it/QkdVXJ
4
Load more