Professor of Pathology&Lab Medicine, Human Genetics and Computational Medicine at UCLA. Views my own.
Los Angeles
Joined November 2012
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We offer an individual-level interpretation of polygenic score (PGS) transferability across genetic ancestries:
PGS accuracy varies individual-to-individual across the genetic-ancestry continuum, even in populations usually labeled as homogeneous.
1/
nature.com/articles/s41586-0…
Bogdan Pasaniuc retweeted
Very grateful to have worked on this project with such a fantastic group of people!
Excited to share a new perspective on Graph Artificial Intelligence in Medicine | Annual Reviews @AnnualReviews - go.shr.lc/4g0KpLV
Led by fantastic @ruthie_johnson @_michellemli @ayushnoori @oq_35 @harvard_data @broadinstitute @KempnerInst @HarvardDBMI
Bogdan Pasaniuc retweeted
Excited to announce the Penn Postdoctoral Fellowship in Genetics! We seek to empower and nurture talented early-stage researchers to pursue cutting-edge research in our department.
Learn more here, due Jan. 15.
med.upenn.edu/apps/my/bpp_po…
Bogdan Pasaniuc retweeted
Very excited to see isoTWAS published today in @NatureGenet!
Big power gains for complex trait mapping via multivariate modeling of isoform-level regulation, particularly in brain.
Fantastic effort led by @bhattac_a_bt & collab with @bpasaniuc
rdcu.be/dsrzZ
Bogdan Pasaniuc retweeted
Welcome back! If you're looking for a faculty position in the intersection of computational methods and medicine [broadly], consider applying to UCLA CompMed's faculty search! It's a unique department spanning both SoE and SoM. Search is open rank recruit.apo.ucla.edu/JPF0891…
Bogdan Pasaniuc retweeted
You may ask yourself, what is this Connect thing? dceg.cancer.gov/research/who…
Bogdan Pasaniuc retweeted
Want develop methods while building a rigorous quant foundation? CompMed’s Biomath PhD program is looking for math/stat/bio/CS students. Our new site outlines our three major Focu Areas, Imaging and Biomed Data, Math and Systems Modeling, and Comp Genomics compmed.ucla.edu/phd/overvie…
Excited for the NHGRI workshop on Advances in Genetic Architecture of Complex Traits @NeuroMinded
genome.gov/event-calendar/ad…
Bonus: you may see some of @SashaGusevPosts tweets in my slides
xitter.cf/SashaGusevPosts/status…
polygenic👏score👏means👏cannot👏be👏compared👏across👏populations
[Figure modified from Ding et al. pubmed.ncbi.nlm.nih.gov/3719…]
Bogdan Pasaniuc retweeted
polygenic👏score👏means👏cannot👏be👏compared👏across👏populations
[Figure modified from Ding et al. pubmed.ncbi.nlm.nih.gov/3719…]
Bogdan Pasaniuc retweeted
Excited to share that our new multi-group multi-trait #finemapping method MGflashfm, that uses #GWAS summary statistics, has been published online at @NatureComms
@FZ_Cambridge, @OpeSoremekun, @tchikowore1, @SFatumo, @InesBarroso4, Andrew Morris
@MRC_BSU
rdcu.be/dqK8J
Bogdan Pasaniuc retweeted
Read more about this new *LDpred2* work, now published in @AJHGNews 🥳
authors.elsevier.com/a/1i372…
Bogdan Pasaniuc retweeted
@raungar and I are thrilled to share our paper on the trainee-led course on genetics, ethics, and society that was developed at Stanford: biorxiv.org/content/10.1101/… (1/9)
Bogdan Pasaniuc retweeted
I'm writing a molecular perspective on heritability, behavior, (and eventually) race/ancestry, group differences. The idea is to start with what we've learned from genetic data and then work backwards to what we used to know from classical studies.
gusevlab.org/projects/hsq/
Bogdan Pasaniuc retweeted
Very excited to share this work by @JingyouR that is the first in a hopefully very long collaboration with @willowcoyote! Hard to believe this started ~ a year ago during lunch at a @HHMINEWS meeting!
xitter.cf/JingyouR/status/171899…
Meet Rosace, a robust deep mutational scanning analysis tool that incorporates positional information and mean-variance shrinkage. Check it out if you are running DMS experiments or handling DMS data! (1/n)
biorxiv.org/content/10.1101/…
Bogdan Pasaniuc retweeted
Meet Rosace, a robust deep mutational scanning analysis tool that incorporates positional information and mean-variance shrinkage. Check it out if you are running DMS experiments or handling DMS data! (1/n)
biorxiv.org/content/10.1101/…
Congratulations Dr @yi_ding_ on successfully defending her PhD thesis: "Uncertainty, portability, and ancestry in polygenic scoring".
Many thanks to @TheBoutrosLab, @GeschwindLab and @sr_sankararaman for amazing mentorship!
Bogdan Pasaniuc retweeted
There's still time to apply! Our TT [open rank] position for a _computational_ geneticist at UCLA closes Oct 31. Apply if you focus on any computational genetics work and ignore the pigeon holing in the application. Feel free to reach out with questions.
recruit.apo.ucla.edu/JPF0848…
Bogdan Pasaniuc retweeted
📢 New @AJHGNews
📰Estimating heritability explained by local ancestry and evaluating stratification bias in admixture mapping from summary statistics
🧑🤝🧑@TszFungChan7 @CharlestonCWKC @nmancuso_
#HAMSTA
cell.com/ajhg/fulltext/S0002…
Bogdan Pasaniuc retweeted
📢New @AJHGNews
📰A scalable approach to characterize pleiotropy across thousands of human diseases and complex traits using GWAS summary statistics
🧑🤝🧑@nmancuso_ & colleagues
cell.com/ajhg/fulltext/S0002…
Bogdan Pasaniuc retweeted
NHGRI is having a workshop - Advances in the Genetic Architecture of Complex Human Traits - organized by @NancyGenetics, @lorin_crawford, @molly_przew, and Peter Visscher.
Thurs 16th - Fri 17th November
Register for the webinar here: nih.zoomgov.com/webinar/regi…
