Platelets as key modulators of the immune response 🤯
Amazing work from the Franklin lab!
This Post is from an account that no longer exists. Learn more
This is super cool! 🤩
Biggest paper yet from the lab out now in @ImmunityCP! It is a massive #openscience resource on #tissueTregs, and what makes #Tregs tick in the #tissues. Spoiler-alert: Tissue Tregs are really different from what we all thought. 🧵 1/21
sciencedirect.com/science/ar…
Ernesto Picon-Galindo retweeted
Thrilled that our huge team effort with @Kornfeld_JanW is out in @NatMetabolism 🥳 supported by @TRR_BATenergy A huge thank you to all collaborators! If you want to know how a truncated AC3 isoform regulates #BAT function, have a look here nature.com/articles/s42255-0…
Ernesto Picon-Galindo retweeted
In @JExpMed, Rodrigo, @chrkurts et al @UniklinikBonn develop dual fluorescence reporter mice to identify cells that secrete and/or sense chemokines and to delete producing cells. hubs.la/Q02v2HHl0
#InnateImmunity #inflammation #InfectiousDisease #HostDefense
Ernesto Picon-Galindo retweeted
Excited to share our review on NLRP3 #inflammasome signalling in #Alzheimer’s disease with @eickelatz. Check it out to learn the latest on NLRP3 activation, the inhibitors in #clinical trials and new NLRP3-targeted therapies under development
sciencedirect.com/science/ar…
Ernesto Picon-Galindo retweeted
Excited to share our latest research published today in
@nature on sex-differences in adipose resident Treg cells @TheDohertyInst @WEHI_research @ASImmunology. Big thanks to our collaborators from
@MonashPharm @PeterMacCC @Austin_Health @harvardmed
nature.com/articles/s41586-0…
🤩
An exceptional review of how obesity revs up the immune system and inflammation, including what happens with weight regain
science.org/doi/10.1126/scit… @ScienceTM @ahasty4 @VUMChealth
Ernesto Picon-Galindo retweeted
Where do #TissueTregs come from? The previous standard model is the "seeding and specialisation" model, where #Tregs enter from tissues, turn on a dedicated transcriptional program per #tissue, and dwell indefinitely in that tissue as specialised cells.
1/3
Congrats! 🎊
I am very happy to share our recent paper published in Nature Communications about G4s and their role in DNA damage! 🥳 Check it out! @PaeschkeL
nature.com/articles/s41467-0…
Ernesto Picon-Galindo retweeted
The first publication from our #FOR5547 - review about primary #cilia dynamics @jayslab2 @MickLab @NathalieJuYa @RosiFeistel @WalentekLab @BernhardScherm1 @anne_grapin @friedrich_group @lab_mass @muellerRom @helenmaysimera
embopress.org/doi/full/10.15…
Ernesto Picon-Galindo retweeted
We made it🎉 excited to announce that @jayslab2 @MickLab @NathalieJuYa @RosiFeistel @WalentekLab @BernhardScherm1 @anne_grapin @friedrich_group @lab_mass @muellerRom @helenmaysimera #MiriamSchmidts will start a research unit #FOR5547 working on #cilia @DFG_public
Ernesto Picon-Galindo retweeted
Medullary TECs have the potential to differentiate into various types of molecularly distinct and functionally defined cells that contribute to both induction of central tolerance & homeostasis of other thymus-resident populations @Nature
nature.com/articles/s41586-0…
Ernesto Picon-Galindo retweeted
Interested in working on primary #cilia signaling funded by @NSF @dfg_public, combining genetics, proteomics, optogenetics at @TamaraGenes @MickLab @DagmarWachten ? Apply now! Our labs have open calls for a #PhDposition and a technician. Please get in touch if you are interested!
Ernesto Picon-Galindo retweeted
BREAKING: The drug semaglutide, made by 🇩🇰 Denmark's Novo Nordisk, is found to cut risk of heart attacks and strokes by 20%, possibly making it one of first drugs to have effect of both reducing cardiovascular events and helping with weight loss.
Check out the last post from @ImmunoSens Blog! Former colleague and good friend, @fourmidouble wrote about the interwiring between Philosophy and Immunology.
Taking the red PinS as a post-doc in biology immunosensation-blog.de/taki…
Ernesto Picon-Galindo retweeted
'In vivo hematopoietic stem cell modification by mRNA delivery' science.org/doi/full/10.1126…
Ernesto Picon-Galindo retweeted
Utilizing both electron microscopy and MERFISH, we're nearing Feynman's dream of a more efficient EM! Take a look at our research on brain injuries below 🔥 please RT!
Is ultrastructure of the cell mirrored by its transcriptional state? What is the relationship between molecular and structural phenotypes? How do they localize in the tissue and reorganize after brain injury? A thread on our new study…🧵
nature.com/articles/s41467-0…
