@LabListoni
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🇦🇺🇧🇪🇬🇧👨🔬🌈 Professor of Pathology & Head of Immunology at @Cambridge_Uni. Fellow & Welfare Tutor at @Catz_Cambridge. Founder & CSO at Aila Biotech.
Cambridge, England
Joined December 2018
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Two post-doc positions available in our lab!
It is a supportive environment and one which boosts careers! Historically, of our ~30 post-docs 27% have gone on to tenure-track positions, 27% did another post-doc, and 42% have gone on to positions in biotech or pharma.
Adrian Liston retweeted
Missed our latest Unravelling T Cell Recognition seminar?
Prof Chihiro Motozono, discusses the molecular basis of T cell antigen recognition and immune escape in viral infections, with lessons from SARS-CoV-2.
The full seminar is now freely available 👇
youtu.be/x-Ox8MwcHjc
🤖 Made with AI
I don't like how PhD defences are done in the UK. It is an ordeal without actually being a quality control step.
Adrian Liston retweeted
Today, we’re celebrating Jeffrey. 💙
A little boy whose life was far too short, but whose story changed the lives of countless others around the world.
Because of Jeffrey, families have greater awareness of primary immunodeficiency. Because of Jeffrey, babies around the world have the opportunity to be identified through newborn screening before they become seriously ill. And because of Jeffrey, children and families facing primary immunodeficiency have a community that continues to advocate for them.
His legacy lives on in every diagnosis made earlier, every family given answers, and every child given a chance.
Happy Birthday, Jeffrey. Your story continues to make a difference every single day. 💙
#ScreenEveryBaby
I just had to show off my latest purchase - the only water bottle around for lovers of lymph!
etsy.com/uk/shop/AisforAntib…
Adrian Liston retweeted
A great opening of our Immune Alliance Meeting 2026 in Bayreuth with Nobel Laureate Shimon Sakaguchi presenting his latest work on the role of Treg cells in cancer immunity. #immunology
Adrian Liston retweeted
The convergence on PRDX1 from this study and ours using completely different methodologies is remarkable! science.org/doi/10.1126/scie…
New findings on antioxidant suppression from Julian Lum: CRISPR screen of factors sensitising T cells to suppressive activity of human ovarian cancer ascites fluid identifies PRDX1 whose deletion increases intracellular ROS and enhances T cell function! biorxiv.org/content/10.64898…
Adrian Liston retweeted
We have a new book, and it is a cute one!
"Cell Mates" is the alphabet book all #immunology parents need!
amazon.co.uk/dp/1066702837/
We have a new book, and it is a cute one!
"Cell Mates" is the alphabet book all #immunology parents need!
amazon.co.uk/dp/1066702837/
And look, I know what you are going to say. "That Regulatory T cell is too cute! I need it on a mug!" So I am happy to also introduce the merch over at Etsy
etsy.com/shop/AisforAntibody
Silly take. Optimising every step is unnecessary. Applying prior principles, getting a functional protocol, and then sticking to it without needlessly troubleshooting is a perfectly scientific approach.
Bunsen burners don’t reduce contamination. It was all an illusion. My biology teacher was wrong.
This isn’t surprising, though. So much of biology, and the way we do experiments, claims to be “scientific” but is actually swaddled in mysticism.
Just walk into a laboratory and watch biologists for a day; they will do all sorts of weird rituals that — if you ask them to explain — will elicit no answer other than, “Well, that’s the way I was taught to do it.” Why are washes always five minutes long, for example? Why are they always done in groups of three? Did anybody actually ever measure this stuff?
The Bunsen burner wasn’t even invented for its modern use. Robert Bunsen, a German chemist, invented it in the 1850s to heat up his chemical reactions. Microbiologists later used it to flame and sterilize instruments, which makes sense. And then there was all this debate and controversy about Pasteur’s swan-neck flasks, and this idea that microbes were floating in the air and contaminating things, and so microbiologists decided to take the Bunsen burners they had used to sterilize instruments and just …. put the open flames on their benches to sterilize the air. But this was pure mysticism. Nobody ever actually studied whether or not this worked.
Someone ought to open up a lab and raise money to run “mysticism experiments.” Like, how bad is it (really) if we don’t wash things for five minutes in three cycles? How bad would it be if we didn’t incubate with antibodies at 4 degrees Celsius overnight? Why do cells eventually saturate in LB media? (Some people argue it’s because they run out of carbon, but others claim that's totally a lie and it's actually the magnesium.)
Much of experiment is tacit illusion.
"The Professor, The Pipette, and the Path Not Taken" has readers choosing to work in research, developing spin-out companies, becoming a professor or leave science altogether. The hundreds of paths through the book lead to a range of alternative endings.
biologist.rsb.org.uk/adrian_…
Adrian Liston retweeted
Delighted to share new work published in @ScienceMagazine entitled 'Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species,' led by @XanWesolowski in the lab science.org/eprint/YQNFAHKNF…
Someone only just found out that @Nature does science journalism (the best science journalism around). But they've only been doing it for 150+ years...
Interesting failure of governance at @Nature. Scientists peer review for the scientific journal for free--building up the prestige of the brand--while the Editor-in-Chief & her team get to trash the brand with politicised opinion journalism.
nitter.cf/SashaGusevPosts/status…
I've also seen plenty of times where the directed hypothesis and validation came first, then 'omics was done and thrown in to be the first figure of a paper. Trying to work out the history of science from published papers is problematic!
"There's this concept that circulates that if you don't ace your exams or get into the top university, then basically your whole career is burnt bread," Liston explained. "That's not a healthy framework."
That misconception became the spark for the book.
the-scientist.com/a-stem-car…
Sunlight is the best disinfectant. Revealing corrupt practices needs to be recognised as an act of bravery which ultimately makes institutions stronger.
Cambridge University's problems laid bare
There's a troubling culture of institutional self-protection, with HR sidelining complaints and protecting the University’s reputation — while those who speak up for its core values and mission face retaliation
thetimes.com/uk/education/ar…
Adrian Liston retweeted
Two post-doc positions available in our lab!
It is a supportive environment and one which boosts careers! Historically, of our ~30 post-docs 27% have gone on to tenure-track positions, 27% did another post-doc, and 42% have gone on to positions in biotech or pharma.