Eoghan Harrington (@eoghh) header
Eoghan Harrington (@eoghh) profile picture

Current: Oxford Nanopore, Previous: Flatiron Health, 23andMe, Stanford, EMBL, TCD. Opinions my own

New York, USA
Joined July 2010
Eoghan Harrington retweeted
Now, @nanopore only approaches are producing the best t2t automated assemblies ever produced with 30 contigs and 5 scaffolds! 🤯🤯🤯🤯 #nanoporeconf
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Eoghan Harrington retweeted
What if you could characterise brain tumours in hours, rather than weeks? And in doing so allow neurosurgeons to adjust their surgical strategies on the spot. Here, researchers showed that they were able to do just that by leveraging nanopore technology: bit.ly/46BH8x4
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Eoghan Harrington retweeted
Come and work with us! It's an amazing team and an incredible opportunity to develop computation tools that will have real world impact in a wide range of areas as well as being part of pushing the boundaries of what is possible with DNA and RNA sequencing.
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Eoghan Harrington retweeted
✂️Splice splice baby!✂️ New paper just out in @CellStemCell integrating @nanopore long read single-cell isoform mapping into our broader genotype-phenotype vision for clonal mosaicism ! authors.elsevier.com/a/1hat9…
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Eoghan Harrington retweeted
Here @BanfieldLab used #nanopore sequencing to study 'the nature and existence of enigmatic genetic elements' (Borgs) in soil. They assembled 7 new curated Borg genomes, revealing extensive DNA methylation that differentiates them from their host archaea, Methanoperedens. 🧵1/2
Borg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires biorxiv.org/cgi/content/shor… #bioRxiv
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Eoghan Harrington retweeted
Another LOADED update from the @nanopore EPI2ME team with wf-metagenomics and wf-somatic-variation getting new functionality & our desktop app getting easier for Windows users & displaying workflow progress. All this and more here: labs.epi2me.io/epi2me-23.07-… We’re also hiring…
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Eoghan Harrington retweeted
Bacterial epigenomes are very cool and extremely diverse! And you get them for free when you do @nanopore sequencing 🧫🧬
Our paper is out today! Bacterial genomics has exploded in recent years, but, with a few exceptions, researchers have ignored bacterial epigenomes. We analyzed hundreds of Bacteroides (and friends) isolates and found astonishing epigenomic diversity. rdcu.be/dgvAy
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Eoghan Harrington retweeted
Come talk 🦠💻🧬 with me at #ASMicrobe! I'll be: 1. At my poster: adaptive sampling, MAGs, and host methylome from human microbiomes (Sat, HMB06) 2. Intro-ing metagenomics pipelines for Nanopore data (Sat/Sun, Data for Breakfast, 10:05-10:20 @ booth 2207) 3. At the Nanopore booth
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Eoghan Harrington retweeted
#ASMicrobe folks: come see @christine_y_he at her poster to learn how @nanopore sequencing of human microbiome samples can simultaneously: - Deplete host DNA to get more microbial reads - Generate genome-resolved assemblies - Provide host DNA methylation from the proximal tissue
Come talk 🦠💻🧬 with me at #ASMicrobe! I'll be: 1. At my poster: adaptive sampling, MAGs, and host methylome from human microbiomes (Sat, HMB06) 2. Intro-ing metagenomics pipelines for Nanopore data (Sat/Sun, Data for Breakfast, 10:05-10:20 @ booth 2207) 3. At the Nanopore booth
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Eoghan Harrington retweeted
47,000 nanopore genomes processed a year (84k so far).
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Eoghan Harrington retweeted
New addition to the Oxford Nanopore Open Datasets: Genome in a Bottle Ashkenazi Trio, accessible via @AWSCloud. Sequencing was performed using #PromethION Flow Cells, (~200Gb yield each), Kit V14 chemistry & analysis driven by @nextflowio. Read here: bit.ly/3E96oyG
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This should save me some time
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Eoghan Harrington retweeted
Incoming…
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Eoghan Harrington retweeted
Blog post - 20 years of open science or how we haven't radically changed the way we do science online. Thoughts on how we don't seem to be using the internet to its fullest potential in scientific collaborations evocellnet.com/2022/11/20-ye…
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Eoghan Harrington retweeted
Come and join us – awesome community, great resources, and a cool city! Besides, in this crazy world is there a better place to be than Canada? 🇨🇦
The Donnelly Centre is inviting applicants for three (3!) faculty positions (tenure track) in #compbio & #genomics. ✅ great science ✅ great colleagues ✅ great city To learn more about the positions and how to apply👇 bit.ly/DonnellyRecruitment20… Deadline is January 16, 2023.
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Eoghan Harrington retweeted
Excited to share our paper, out today in @Nature, where we characterize transcriptome variation in human tissues by long-read sequencing. Huge thanks to @g_dafni @beryl_bbc Garrett Garborcauskas @dgmacarthur and other collaborators. 🧵 nature.com/articles/s41586-0…
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Eoghan Harrington retweeted
Really happy to see RRMS out! I'm sure will enable a bunch of new applications in epigenetics 🧬 Check out all the advantages of this adaptive sampling method for cost-effective methylation calling using #nanopore technology ! Spoiler: lots!
The #NanoporeAppsTeam are excited to release Reduced Representation Methylation Sequencing (RRMS) to uncover changes in methylation patterns associated with changes in gene expression and diseases such as cancer: bit.ly/3yL6kD9 (Community login required) 1/7
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Eoghan Harrington retweeted
Looking for a motivated person to join my #Algorithms and #MachineLearning team to further improve our industry leading @nanopore modified base detection capabilities!
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