Principal Research Fellow @uclcs @UCL_Hawkes | Disease progression modelling | Heterogeneity | Neurodegenerative diseases | Machine learning
Joined July 2018
- Tweets30
- Following157
- Followers139
- Likes44
Alex Young retweeted
#AAIC2025 Wednesday TALK by @chris_ucl from @POND_UCL: 2pm, session 4-23-DEV.
"Longitudinal trajectories of advanced cortical diffusion-weighted imaging measures of tissue microstructure in pre-symptomatic autosomal dominant Alzheimer's disease"
Alex Young retweeted
#AAIC2025 Wednesday POSTER by @DrMaitreiKohli from @POND_UCL & MANIFOLD lab:
Wednesday-410. "AutoML-Multiverse: Model Agnostic Framework for Optimizing Individual-level Alzheimer's Disease Classification"
Alex Young retweeted
#AAIC2025 Monday POSTER by @LawrenceBinding from @POND_UCL:
Monday-437. "Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath)"
A new SuStaIn... :-)
Two postdoc positions available developing and applying AI and machine learning tools for neurodegenerative disease research with Prof Danny Alexander and I.
Closing date 30th July.
ucl.ac.uk/work-at-ucl/search…
ucl.ac.uk/work-at-ucl/search…
@fishpiechicken
Alex Young retweeted
‼️PhD Position now available in my lab‼️
Do you like:
* Neurodegenerative disease?
* Neuroimaging and/or multi-omics?
* AI and data-driven life science?
Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse?
Apply here: lu.varbi.com/what:job/jobID:…
Please rt/share 🙏
Alex Young retweeted
@AndrewZalesky and I will organize a symposium on "Unraveling brain heterogeneity across scales, systems, and diseases" at OHBM 2025! We have a great line-up of speakers (@YoungAlexL @chrisdav66 @yetianmed, Maria Di Biase, and myself) who will discuss cutting-edge topics, including AI/ML subtyping, multi-organ, and multi-omics modeling!
Check info here: ww6.aievolution.com/hbm2501/…
See you in beautiful Australia this summer/winter! @OHBM
Alex Young retweeted
Estarellas et al. report that an adapted Subtype and Stage Inference algorithm accommodates missing data in multimodal #Alzheimersdisease studies. @mar_estarellas @UCLMIGPOND @NeilOxtoby @jmschott @fishpiechicken @YoungAlexL
edin.ac/3SjesUI
Alex Young retweeted
I am hiring a research technician to help process and analyze multimodal neuroimaging data. Please RT!!
* Great opportunity to gain research experience pre-PhD
* Access to exciting data
* Opportunities for independent projects
Apply here:
lu.varbi.com/en/what:job/job…
Alex Young retweeted
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology
@SEMastenbroek strikes again!
Using SuStaIn modeling of neuropathological data (n=814) we show substantial heterogeneity in the temporal spread of Lewy body pathology, with 81.9% showing earliest pathology in the olfactory bulb while 18.1% initially exhibited abnormalities in brainstem regions.
Link to @biofinder_study thread > xitter.cf/biofinder_study/status…
Link to paper @NatureComms > nature.com/articles/s41467-0…
w/@BannerHealth, @AlzheimerAms @_JakeVogel_, @LECollij, @YoungAlexL, @cece_tremblay, @FBarkhof & @OskarHansson9
🚨Paper alert
Led by PhD student @SEMastenbroek “Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology” now published in @NatureComms !
nature.com/articles/s41467-0…
We found a novel brainstem-first Lewy body subtype 👇
Alex Young retweeted
The first @eumind_congress takes place on 25-27 September in Caen, Normandy. The deadline for submitting your neuroimaging abstracts and travel awards is today. Be sure to submit!
eu-mind.org/abstracts-submis…
Alex Young retweeted
Extremely happy to see this one out at last!!!🎉🎊
Here, we showed that a single CSF draw 💉is sufficient to accurately stage participants along the #Alzheimer's continuum.
This has been a long and tough journey, but totally worth it to finally share it with the whole community☺️
New publication in @NatureAging led by @gesalbla ‼️
Here, we propose and validate a staging system for #Alzheimer's disease based on fluid biomarkers nature.com/articles/s43587-0…
A 🧵 ...
Alex Young retweeted
‼️ Postdoc ad // Please RT/circulate ‼️
Are you interested in
* Big euroimaging and multi-omic data?
* Neurodegenerativ disease?
The @biofinder_study is looking for a talented postdoc to sink their teeth into some rare and exciting data!
Apply here:
lu.varbi.com/en/what:job/job…
Alex Young retweeted
New pre-print alert! The aim of this study was to identify imaging subtypes of CBS based solely on a data-driven assessment of atrophy patterns, to test the hypothesis that modelling disease subtype and stage jointly would provide information on underlying pathology in CBS.. 1/7
Distinct spatiotemporal atrophy patterns in corticobasal syndrome are associated with different underlying pathologies medrxiv.org/cgi/content/shor… #medRxiv
Alex Young retweeted
Are you an early-career scientist interested in learning about the latest advances in medical image computing? The 10th UCL Medical Image Computing Summer School (MedICSS 2024) will take place from 1st – 5th July 2024 in person in Central London. ucl.ac.uk/medical-image-comp…
Alex Young retweeted
Data-driven modelling of neurodegenerative disease progression: thinking outside the black box — a Review by Alexandra L. Young, Neil P. Oxtoby, Sara Garbarino, Nick C. Fox, Frederik Barkhof, Jonathan M. Schott & Daniel C. Alexander
go.nature.com/492x4yg
