Aussie scientist and musician (@Oxtobymusic) based in the UK. UKRI Future Leaders Fellow at @POND_UCL, @CMICUCL, @UCLCS (co-leader: @EDADS_jpnd, @Euro_POND).
London-ish, U.K.
Joined November 2008
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Goldilocks DPM: semi-automated tool to find the sweet spot between your #Alzheimer's data and disease progression model hyperparameters. Includes a worked example using SuStaIn.
github.com/noxtoby/goldilock…
Open source tool, first described at #AAIC2024: doi.org/10.1002/alz.092363
If you like using biomarker ratios for Alzheimer’s disease progression analyses, then check out our new normative statistic that makes efficient use of an entire panel of biomarkers
nature.com/articles/s41540-0…
Neil Oxtoby (Toybox Science) retweeted
After success in Phase 2, trontinemab is being tested in Phase 3 for early AD. A prevention trial—PrevenTRON—will start later this year. ow.ly/gPsB50ZsufG
I'll have two computational postdoc positions opening up soon in the @POND_UCL team. One on Alzheimer's clinical trials (data-driven disease models and digital twins). The other on Early Detection via digital/wearable tools. Hit me up for a chat if you're interested.
I'll have two computational postdoc positions opening up soon in the @POND_UCL team. One on Alzheimer's clinical trials (data-driven disease models and digital twins). The other on Early Detection via digital/wearable tools. Hit me up for a chat if you're interested.
My team’s latest release of free software for unravelling the mysteries of neurodegenerative diseases is from Isaac Llorente Saguer: joss.theoj.org/papers/10.211…
Fireside chat at #ADPD2026 including Pharma sees them nodding along with comments about sharing data.
I spat out my coffee
DeepMind at #ADPD2026 claiming that their A.I. Co-Scientist did a particular 10 years of research in 2 days…
…did Co-Scientist have to write grants and teach students in parallel?
Neil Oxtoby (Toybox Science) retweeted
"Do the Evolution", Yield 1998
Watch the full music video at: pj.lnk.to/DoTheEvolutionHD23…
Neil Oxtoby (Toybox Science) retweeted
A mystery signal is showing up in ADNI amyloid PET scans using NAV-4694. No one knows why. @HAIconference @UCSF ow.ly/tky250Yasbk
Mistaken! There is at least a 4th option, @RussInCheshire — tax wealth, not work. Check out @garyseconomics
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Neil Oxtoby (Toybox Science) retweeted
I don't think Twitter works for this anymore, but I had luck with it just <1 year ago, so let's try again!
I am recruiting multiple postdoc positions in Alzheimer’s and Dementia, Epidemiology, and Translational Neuroscience!
Plz RT!
recruit.ap.uci.edu/JPF09486
Neil Oxtoby (Toybox Science) retweeted
#AAIC2025 Wednesday POSTER by @DrMaitreiKohli from @POND_UCL & MANIFOLD lab:
Wednesday-410. "AutoML-Multiverse: Model Agnostic Framework for Optimizing Individual-level Alzheimer's Disease Classification"
Neil Oxtoby (Toybox Science) retweeted
#AAIC2025 Wednesday TALK by @chris_ucl from @POND_UCL: 2pm, session 4-23-DEV.
"Longitudinal trajectories of advanced cortical diffusion-weighted imaging measures of tissue microstructure in pre-symptomatic autosomal dominant Alzheimer's disease"
Neil Oxtoby (Toybox Science) retweeted
#AAIC2025 Monday POSTER by @LawrenceBinding from @POND_UCL:
Monday-437. "Uncovering regional atrophy not explained by tau deposition using Additional Pathology Inference (AddiPath)"
A new SuStaIn... :-)
Check out @YoungAlexL’s talk at #AAIC2025 tomorrow. Event-based models with time!
#AAIC2025 Monday TALK by @YoungAlexL from @POND_UCL: 4:15pm, session 2-32-FRS-A.
"Disease timeline modelling of amyloid and tau PET reveals dynamic timescales of amyloid and tau accumulation in Alzheimer's disease"