We are a molecular virology lab led by @samjwilsonphd. ISGs and viruses (SARS-CoV-2, HIV-1, IAVs). https://xitter.cf/t.co/Qyk3CTPkHm
Cambridge, England
Joined January 2017
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Pinned Tweet
New @wilsonlabcvr paper. Our work, led by @virologist_atu, showing that the prenylated variant of OAS1 can sense SARS-CoV-2 and protect against severe #COVID19 is out in Science:
science.org/doi/10.1126/scie…
#CVRCovidResponse
🧵 (with some new bits)
Wilson Lab retweeted
Our new paper @JExpMed - Nasal viruses & bacteria are very common in children (90% of symptomatic and ~50% of asymptomatic <5yrs!), and activate nasal defenses, which may have protected from #Covid_19 @YaleMed @Yale_LabMed @YaleIBIO @YalePediatrics
rupress.org/jem/article/221/…
Wilson Lab retweeted
I always say jobs in my lab are great opportunities but this one really is. The last incumbent published 3 1st-author @Nature papers, found a treatment for Covid, and now has a senior job in pharma.
Quantitative geneticists - please consider joining us!
jobs.ac.uk/job/DIL188/postdo….
Wilson Lab retweeted
🔔'Tis the season...to apply for a new job?! My group @MedCambridge is recruiting for 2 posts:
Postdoc: jobs.cam.ac.uk/job/44181/
Research assistant: jobs.cam.ac.uk/job/44250/
Both roles will seek to improve our understanding of coronavirus cross-species transmission. #preparedness
Wilson Lab retweeted
A lovely piece of work that places interferon-mediated antiviral immunity to betacoronaviruses into evolutionary & ecological context.
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
Wilson Lab retweeted
Really interesting thread and paper about an anti-coronavirus gene in humans that bats lost millions of years ago, which could help explain why bats are such prodigious reservoirs of coronaviruses, posing a constant threat of spillover into humans.
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
Wilson Lab retweeted
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
New WilsonLabCITIID publication led by @SpyrosLytras where we reconstructed an ancient OAS1 from the ancestor of modern horseshoe bats and demonstrate it possessed anti-SARS-CoV-2 activity.
journals.plos.org/plosbiolog…
This study builds on our previous work demonstrating human prenylated OAS1 (p46) inhibits SARS-CoV-2 whereas the nonprenylated (p42) form does not.
science.org/doi/10.1126/scie…
The nonprenylated human OAS1 p42 is not functionally analogous to nonprenylated horseshoe bat OAS1.
Wilson Lab retweeted
One thing the pandemic forever changed for me was my perspective on sharing biomaterials (tools and reagents) from publications. I’ve written about this, with co-author Alexander Harms (@AHarms485), in our new PLOS Biology perspective:
Could better biomaterial sharing improve the scientific community?
@Lab_Rihn_th & @AHarms485 draw on their experiences of sharing #biomaterials to discuss the advantages, challenges, and ways sharing could be more actively promoted and rewarded.
plos.io/3F9HajT
ALT A summary of the benefits and challenges associated with biomaterial sharing. Challenges include administrative burden, time, effort, cost, misuse/misrepresentation, and ethical/intellectual property considerations. Benefits include new ideas/collaborations, improved reproducibility, equity and community, savings in time, money and resources, and maintaining access to materials.
Wilson Lab retweeted
Join our EVIR team in the fight against the Crimean-Congo hemorrhagic fever! We're looking for a Research Assistant to work on #CCHFV. Contact us for more info or to apply!
Wilson Lab retweeted
Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.
jobs.cam.ac.uk/job/42654/
Deadline Oct 1st 2023
Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.
jobs.cam.ac.uk/job/42654/
Deadline Oct 1st 2023
We'll be invested in supporting your career and development. If you'd like more info, contact @samjwilsonphd, or read our recent papers:
nature.com/articles/s41586-0…
science.org/doi/10.1126/scie…
Wilson Lab retweeted
📢 Exciting job opportunity! 📢
A postdoc position is available in our lab at @Dunn_School @UniofOxford to study influenza virus transcription, genome replication, nuclear export and assembly.
More info: my.corehr.com/pls/uoxrecruit…
Wilson Lab retweeted
✨New title unlocked!!✨ Finally a Dr! Big thanks to @katrina_lythgoe and @rbiek for a great viva and ofc to my wonderful supervisors for the past four years @blJOg @SamJWilsonPhD @robertson_lab!! 😁😁🎉🎉
Wilson Lab retweeted
Join us! A postdoc position between my lab and @QuezadaLab has become available at @uclcancer in London. Please help us characterise the molecular mechanisms through which anti-tumour immune responses are controlled.
To apply
ucl.ac.uk/work-at-ucl/search…
Deadline 14 Sept
Please RT!
