@SamJWilsonPhD

Molecular virologist/Professor working on things that stop viruses (especially SARS-CoV-2, IAVs and HIV-1 ) My own opinions. Lab tweets @WilsonLabCITIID.

 University of Cambridge
mrcppu-covid.bio/
Joined September 2016
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Exciting few weeks, as I will soon become the new GSK Professor of Microbial Pathogenesis at the Cambridge Institute for Therapeutic Immunology and Infectious Disease (CITIID), @Cambridge_Uni @MedCambridge 🎉 And our BTN3A3 work was published in @Nature (doi.org/10.1038/s41586-023-0…)
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Just published in @NatureComms! We show that Usutu virus is the only mosquito-borne flavivirus to resist ISG20-mediated inhibition, thanks to a unique domain in its 3'UTR that protects its genome from degradation. A project led by @JimZPhD at @IRIM_life. rdcu.be/dVMK1
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Why do people seem to be getting sick more often now? For yet another year we are already seeing earlier and significantly higher hospital admissions for respiratory illness than pre-pandemic levels. Are there new mysterious pathogens starting to attack us now? 🧵1/
Graphic of a person's body with a target on their chest and a COVID-19 arrow sticking in the bullseye, depicting an artistic representation of immune dysfunction. Prompt: "Create a graphic of immune dysfunction" by Microsoft Copilot.

ALT Graphic of a person's body with a target on their chest and a COVID-19 arrow sticking in the bullseye, depicting an artistic representation of immune dysfunction. Prompt: "Create a graphic of immune dysfunction" by Microsoft Copilot.

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BREAKING🔔 A new study from G2P-Japan🇯🇵 is out! The preprint will be out so soon, but we first show our results on the efficacy of XBB.1.5 monovalent vaccine - comparison between infection-naïve and XBB-infected individuals. Please retweet/repost🔥 1/
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Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses. jobs.cam.ac.uk/job/42654/ Deadline Oct 1st 2023
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It was an honour representing the @CVRinfo @UofGlasgow at the @Els_Vaccine 17th Vaccine Congress, here in Glasgow! As a non-vaccinologist I got to learn a great lot about vaccines from all the other speakers! #17VaccineCongress
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In 1986 Staeheli et al seminal MX1 paper noted re: IFN/ISGs “it is not known...how many of these proteins are required for protection against a particular virus”. 37 yrs later, Phd student @mattbmcdoug's new paper shines a light. 1/3 embopress.org/doi/full/10.15…

Interferon inhibits a model RNA virus via a limited set of inducible effector genes

EMBO Reports - Interferons control viral infection by inducing the expression of antiviral effector proteins encoded by interferon‐stimulated genes (ISGs). The field has mostly focused on...

link.springer.com
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The Greek island of Rhodes continues to burn. My wife @theodora_nyc was supposed to be on vacation, visiting her family, but instead helping with the relief effort theguardian.com/weather/2023…
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Thanks to everyone who mentored me along the way, with a special shoutout of thanks to my key mentors @PaulKellam_2 (PhD), Greg Towers (@towerslab, postdoc1) and @PaulBieniasz (postdoc2).
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And most importantly, thanks to my wife (@Lab_Rihn_th) and everyone from the @wilsonlabCVR & @Lab_Rihn_th groups (past and present) and all of our colleagues at @CVRinfo for the wonderful journey.
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Best naughty Elf on the shelf! 😁👇
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Sam J Wilson retweeted
Lionesses
@Lionesses31 Jul 2022
THE FULL-TIME SCENES 🤩

X. It’s what’s happening

From breaking news and entertainment to sports and politics, get the full story with all the live commentary.

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Sam J Wilson retweeted
Towerslab@towerslab28 Jan 2022
Really looking forward to this
UCL Faculty of Medical Sciences@uclmedsci28 Jan 2022
Join us for our next online #FMSLectures: SARS-CoV-2 and COVID-19: What have we learned and what’s next? The lecture will be followed by a Q&A with Prof Greg Towers. 📅 8 February ⏲️ 5-6pm GMT @towerslab @UCLInfectImm Register your free place 👇 bit.ly/3IJeluv
An image of Professor Greg Towers

ALT An image of Professor Greg Towers

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Sam J Wilson retweeted
Rupert Beale@bealelab25 Jan 2022
Replying to @ShamezLadhani
This is flat out incorrect. Vaccines do substantially reduce the risk of infection and transmission, just not 100%. You should delete this tweet.
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😖. Leaflet circulated to parents last week from Scottish government/NHS telling parents NOT to get kids tested if they have symptoms like runny nose or sneezing. What are the top symptoms of Omicron? RUNNY NOSE AND SNEEZING ( doi.org/10.1136/bmj.n3103)
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*sigh* youngest is covid+. That's ~60% of the class now, most of whom have taken it home & infected their (thankfully mainly vaccinated) families. Remind me again how kids don't matter because they don't spread it or get sick? Roll on the family-wide long covid lottery!
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Replying to @adamhfinn
Please reconsider this tweet and clarify. Vaccines may not be sterilising but they are incredibly effective at reducing transmission.
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Replying to @adamhfinn
Adam. This is not accurate or helpful. REACT report out this week clearly shows protection from transmission in vaccinees, albeit with some concerns around waning. It is also the case that exposure is at shockingly high levels, no doubt playing a role. #VaccinesWork
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