#Immunoengineering for better therapies | Associate Prof. of BioE @EPFL | Associate Editor @ESMO_IOTECH | Co-founder of @LemanBiotech
Lausanne, Switzerland
Joined May 2021
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- Following1.6K
- Followers2.7K
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Li Tang retweeted
Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/arti…
Li Tang retweeted
Interested in working with 🐸, 🐭, stem cells, or computational methods 🖥️ to delve into the unknowns of regeneration in our new lab? Looking forward to enthusiastic and ambitious applicants! PhD program applications open! 🔗 phd.tuebingen.mpg.de/14722/p… Please RT! 🙌
Li Tang retweeted
Interested in #singlecell and #spatial #metabolomics ? Then book your calendar for December 10th! – Our online, free event will summarize major achievements of the field in 2024. #metabolism #omics #MALDI #EPFL With @Gio_Dangel0 lab we prepared a fantastic lineup. 🧵 1/5
Li Tang retweeted
#ScienceSaturday
❓ How can we enhance CAR-T cell activity against solid cancers?
➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of solid tumor murine models.
‼️ This exciting approach holds promise for patients with solid malignancies.
Here’s a link to the full article- go.nature.com/3vh5Bdv
@Tang_Lab_EPFL @YugangGUO2 @ZJU_China @DrFredLocke @MarcoRuella @BReinfeld @RPachynski @DrBetofMDPhD
Li Tang retweeted
Our new study published today @Nature uncovers that Transgelin 2 preserves T cell lipid metabolism and anti-tumor activity. Transgelin 2 is silenced in dysfunctional TILs, and restoring its expression enhances CAR-T cell therapy in #OvarianCancer 👇nature.com/articles/s41586-0…
Li Tang retweeted
Doing research in Surface and lnterface Science & Tribology, and want to join @Materials_EPFL @EPFL_en? Send your application by December 1st! All info here:
epfl.ch/about/working/page-2…
Li Tang retweeted
Are you looking for a Faculty Position in Surface and lnterface Science & Tribology? The School of Engineering and The School of Basic Sciences at @EPFL_en are hiring!
Check out the job description for more details:
epfl.ch/about/working/page-2…
Li Tang retweeted
An Fc–IL-4 fusion protein reprogrammed cellular metabolism in terminally exhausted T cells in tumors, leading to enhanced cellular survival, cytotoxicity, and antitumor immunity. Read our summary here 👇 bit.ly/3Yi9uLm @Tang_Lab_EPFL @YugangGUO2 @RongFan8 @GruppSteve
Li Tang retweeted
Dr. Li Tang @Tang_Lab_EPFL presented their work on developing IL-10 secreting CAR-T’s which is now in critical trials with impressive outcomes. @BilkentUniv #Car-T @actsbilkent
We have started the second day of Advanced Cancer Biotherapeutics Symposium with a great and inspiring talk by Prof. Fatih Ezgü on “Current State of Gene Therapies in Clinic” @Gazi_Universite @actsbilkent #genetherapy
Li Tang retweeted
A preclinical study in mice led by @Tang_Lab_EPFL & a collaborative clinical study in patients show that the type 2 immune response, usually associated w/ parasitic infection, is correlated w/ long-term cancer remission actu.epfl.ch/news/unexpected… @epflSV @Yale @Penn @ClevelandClinic
Li Tang retweeted
Today is the day 🤩. Thrilled to share our @Nature paper on Th2 function, CAR-T, & 8-year remission!! Huge team effort w/@GruppSteve @carlhjune @MelenhorstLab @Tang_Lab_EPFL, kudos to my postdoc @Zhiliang_Bai nature.com/articles/s41586-0…
Li Tang retweeted
Here we report the DNA Origami Tension Sensor (DOTS) & measure TCR-pMHC forces in cell-cell junctions! Forces measured using microscopy or flow cytometry! @EmoryChem @YuesongH @salaitalab @EmoryUniversity nature.com/articles/s41565-0…
Li Tang retweeted
Last keynote announcement for #BIC2024:
Prof. Dr. Joachim Spatz, Director of @mpi_mr_hd
His headline talk in the #biomaterials session will focus on Matter to Life: Bottom-up assembly of #syntheticcells.
What an honour - don't miss it! biointerfaces.ch/
Li Tang retweeted
Excited to share our new publication in @Cell! We developed a new single-molecule force spectroscopy method, allowing precise measurement of duration and loading rates of single-molecule forces, revealing protein roles in force dynamics in living cells!
Now online! DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells dlvr.it/T7sT4r
Li Tang retweeted
Excited to share our 1st TCR-T therapy study with Drs. Haopeng Wang and Jizhong Lou, published in Cell Chemical Biology: Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity!
cell.com/cell-chemical-biolo…
Li Tang retweeted
Our work, "Benzene with Alkyl Chains, Is a Universal Scaffold for Multivalent Virucidal Antivirals" led by @yozhu_ ,@frstella is now out in @ACSCentSci 🤩🥳 Congratulations to the whole team 👏 Read the full paper 👇
pubs.acs.org/doi/full/10.102…
Li Tang retweeted
Interested in the translation of #nanomedicine to the clinic?
Prof. Dr. Carole Bourquin from @unige_en @hug_ge will present her latest research on #nanomaterials for #drugdelivery in #cancer and #inflammation in a #keynote talk at #BIC2024.
Join us! biointerfaces.ch/
Li Tang retweeted
What is #DNA #mechanotechnology and how can it help us develop new #biosensors and #nanomedicine?
Prof. Dr. @k_salaita from @EmoryUniversity will share the latest from @salaitalab in his #keynote talk at #BIC2024.
Submit your abstract by March 31: biointerfaces.ch/
Li Tang retweeted
As #keynotespeaker, Prof. Dr. @mastrangelim from @tudelft will headline the #bioprinting and #biofabrication session at #BIC2024!
He will bring us up to speed with the latest advances in Microelectromechanical #organonchip.
📅Sumbit your abstract by March 31, 2024.
