@SpitaleLab

🚀🚀🚀

 Irvine, CA
spitalelab.com
Joined June 2015
  • Tweets4.1K
  • Following1.5K
  • Followers2.6K
378Media
Robert Spitale retweeted
50cent
@50cent10 Jun 2024
My country album on the way Beyoncé ain’t got shit on me. LOL 😆 gunitbrands.com
1,616
4,960
1,048
38,053
2,916,205
Robert Spitale retweeted
Charlie Mace@Charles_Mace4 Mar 2024
Newest ChemRxiv preprint from the lab - "Colorimetric detection of fentanyl using a supramolecular displacement assay". We wanted a simple way for first responders to identify unknown white powders without putting themselves at risk. doi.org/10.26434/chemrxiv-20…

Colorimetric detection of fentanyl using a supramolecular displacement assay | ChemRxiv

Fentanyl is a potent synthetic opioid with an alarmingly low lethal dosage of 2 mg. The equipment necessary to detect fentanyl in field settings (e.g., handheld spectrometers) is restricted to highly...

chemrxiv.org
1
1
4
861
Robert Spitale retweeted
Tim Allen@AllenNeuroLab4 Feb 2024
Projections from thalamic nucleus reuniens to hippocampal CA1 area enable context value updating biorxiv.org/content/10.1101/…

Projections from thalamic nucleus reuniens to hippocampal CA1 area enable context value updating

The ability to extinguish contextual fear in a changing environment is crucial for animal survival. The ‘classic’ neuronal circuit of contextual fear extinction includes the medial prefrontal cortex...

biorxiv.org
4
40
3,612
Robert Spitale retweeted
bioRxiv@biorxivpreprint31 Dec 2023
Comparison of software packages for detecting unannotated translated small open reading frames by Ribo-seq biorxiv.org/cgi/content/shor… #bioRxiv
2
2
6
14,906
How are timescales integrated in biology? Glucose fluxes (sec) are captured by transcription (hrs) — but how? Learn more in our new paper! #LLPS #timescales #proximity #spatiotemporal #condensate #metabolism #metabolon #glucose #glycolysis Thanks to @MDPIOpenAccess @UCI_SPPS mdpi.com/2072-6694/16/1/16
2
21
1
93
14,895
Probing the dynamic RNA structurome and its functions go.nature.com/3TndMva #Review by @SpitaleLab & @danny_incarnato

Probing the dynamic RNA structurome and its functions

Nature Reviews Genetics - In this Review, Spitale and Incarnato discuss how the application of sequencing-based RNA structure mapping methods to entire transcriptomes in living cells is providing...

nature.com
1
23
83
17,503
Robert Spitale retweeted
Ardem Patapoutian@ardemp4 Oct 2023
AI predicts smell from chemical structure! science.org/doi/10.1126/scie…
1
22
5
121
31,615
Beautiful work from @TonyMustoe lab showing how DMS can be used to probe all 4 bases by carefully filtering mutational signatures in MaP experiments! doi.org/10.1093/nar/gkad522

Mutation signature filtering enables high-fidelity RNA structure probing at all four nucleobases...

Abstract. Chemical probing experiments have transformed RNA structure analysis, enabling high-throughput measurement of base-pairing in living cells. Dimet

academic.oup.com
1
9
1
46
7,510
As part of the UCI Office of Research and the Center for Neurobiology Learning and Memory, we are seeking a highly motivated project scientist to oversee the management of the UCI Behavioral Neuroscience Testing Core (ucibtc.org). Apply at: recruit.ap.uci.edu/JPF08388
7
1
20
2,697
Robert Spitale retweeted
Sjogren Lab@SjogrenLab10 Mar 2023
The Sjogren Lab is on the move!! Starting July 1, 2023, we will take up residence at @UCIrvine! California here we come!
8
1
49
8,358
Don’t let this compelling description of where this random link leads keep you from considering an RA position in @FChrisBennett. Translation: This is a job posting for an RA position in his group.
Chris Bennett@FChrisBennett7 Mar 2023
tinyurl.com/2m7xutwt
2
1
20
5,404
Talking to the next generation of female professionals from Compton Unified School District @ Girls in STEAM 2023. GEAR Up! Compton. Our future is in diversity. #GirlsInSTEM #GearUp #UCI
1
2
10
1,555
Robert Spitale retweeted
Keriann Backus@Keribackus27 Feb 2023
Delighted to share our lab's newest preprint chemrxiv.org/engage/chemrxiv…, which was spearheaded by PhD student @Nik_Burton and the result of another great collaboration with @nesvilab!

Enhancing multiplexed cysteine chemoproteomics by uniting FragPipe with solid-phase compatible...

The human proteome harbors tens of thousands of ligandable or potentially druggable cysteine residues. Consequently, pinpointing the optimal covalent molecule for each cysteine residue represents an...

chemrxiv.org
4
11
3
45
21,209
From our Pioneering Investigators collection ✨ 'Cycloaddition enabled mutational profiling of 5-vinyluridine in RNA' by Robert Spitale and first author @mrityug. @SpitaleLab rsc.li/3ECtVIH
1
1
8
3,490
Robert Spitale retweeted
Jeff Mugridge@JeffMugridge23 Feb 2023
📢First preprint from our lab now out! 🥳 We show how the human tRNA-modifying enzyme TRMT1 is recognized & cleaved by the SARS-CoV-2 main protease. Congrats to Angel D'Oliviera who led this work and collaborators Yingkai Zhang & @Lucie_Virevolte! 🧵... biorxiv.org/content/10.1101/…

Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease

The SARS-CoV-2 main protease (Mpro) plays a crucial role in the production of functional viral proteins during infection and, like many viral proteases, can also target and cleave host proteins to...

biorxiv.org
6
11
2
48
7,789
My dad had Frontotemporal Dementia (FTD), and for many years family & physicians didn’t know was causing his dramatic behavioral changes. Now I hope to spread awareness about this horrible disease. Visit @AFTDHope to learn more about #frontotemporaldementia #FTD
2
23
45
4,049
Robert Spitale retweeted
Tim Allen@AllenNeuroLab23 Feb 2023
Replying to @Leila_M_Allen @AFTDHope
Please RT and spread awareness. It’s very clear after the experiences my family had here that neurodegenerative dementias are more varied than convention wisdom has it. My father in law and family suffered from not knowing what was going on for years. FTD is devastating. 💗 🧠
6
8
733
Robert Spitale retweeted
Trader Lab@DJTraderLab16 Feb 2023
The Trader lab is on the move! We will be starting at UC-Irvine in the Dept of Pharmaceutical Sciences in July. Thank you to everyone at Purdue-MCMP for making our time here very successful. New proteasome research to come from SoCal! @UCI_SPPS @UCI_CRI @UCIChemistry
17
6
5
105
20,009
On behalf of our Department of Clinical Pharmacy Practice, we are honored to present to you our very first Department Annual Report! Read here: bpb-us-e2.wpmucdn.com/sites.… #UCISPPS #UCIPharmSci #PharmSci #UCIDCPP
1
5
894
13 yrs ago, I took my first neurosci class as a sophomore at @UCIrvine. @AllenNeuroLab taught Neurobiology of Learning and Memory that summer, and well, it pretty much set the stage for my scientific career. Can’t wait to meet him again, now as a postdoc studying neuroplasticity!
NCF Chapter of SfN@NcfSfn16 Dec 2022
Get ready for the NCF SfN 2023 Conference! It will be held @ UF on Feb 17th 2023. This year's theme is understanding the mystery of memory with Dr. Tim Allen as our keynote speaker. Abstract forms are open NOW & will close Jan 11th, 2023. Plan to present in our poster session!
2
2
1
12
4,130
Load more