@PeronLab

Cortical circuits lab @ NYU CNS. Lasers, neurons, coffee.

 NYU CNS
peronlab.org
Joined October 2019
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1/ How do somatotopically-matched regions of sensory cortex interact? In our most recent paper at @CellReports, @__laurenryan__shows that whisker S1-S2 amplify touch bidirectionally via a specialized population of broadly tuned touch cells. doi.org/10.1016/j.celrep.202…
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Pleased our study is now published. We catalog the structures and cell types innervated by corticospinal neurons (CSNs) of forelimb motor cortex. This research lays an anatomical foundation for many future functional studies from the lab. cell.com/cell-reports/fullte…

Topographical and cell type-specific connectivity of rostral and caudal forelimb corticospinal...

Carmona et al. comprehensively characterize the connectivity of two distinct forelimb corticospinal populations within the brain and spinal cord. Both groups preferentially target inhibitory spinal...

cell.com
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On my way to visit @UNC_Optics and his awesome department @aps_unc. Looking forward to a great visit. Talk is Tue at 4pm, come say hi if you’re in the area! And if you’re a grad student or a postdoc (or an eminent professor looking to relive your postdoc years) I’m hiring!
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The Oldenburg Lab is hiring! If you're interested in using fancy microscopes to stimulate cells and study neural codes let me know. We're looking for an adventurous postdoc who's interested in optics and neurobiology of movement. oldenburglab.com

Oldenburg Lab

Decoding the motor system through the use of multiphoton holographic optogenetics.

oldenburglab.com
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Anyone know of studies comparing same side stimulus and motor action (e.g., sound on right of body and rightward movement) vs. stimulus and action on opposite sides?
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Thrilled to have WenXi's thesis work out in the world! Over the past few years, WenXi has made some cool discoveries about how the brain learns to predict the consequence of an action. 1/9 biorxiv.org/content/10.1101/…

Learning within a sensory-motor circuit links action to expected outcome

The cortex integrates sound- and movement-related signals to predict the acoustic consequences of behavior and detect violations from expectations. Although expectation- and prediction-related...

biorxiv.org
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Excited about our long-brewing paper exploring dynamics in multi-regional neural circuits in a delayed movement task. Driven by@esthersselva, @yiliu021, and including Jennifer Colonell, Nuo Li and @ShaulDr and others (the MAP collaboration): cell.com/cell/fulltext/S0092… (1/7)

Brain-wide neural activity underlying memory-guided movement

A sparse neural network, distributed across major brain compartments, produces tightly orchestrated activity patterns underlying decision-making and movement initiation.

cell.com
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Our work using holographic optogenetics to study recurrent activity in visual cortex is out! This work was only possible due to the great collaboration between @AdesnikHillel and @BrentDoiron labs, especially co-firsts @GHandy50 @willyhendricks and myself nature.com/articles/s41593-0…
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So excited to see the second half of my dissertation work officially out in @CellReports ✨ if you’re interested in Inter-areal communications in sensory cortex check it out 💃🏻 big thanks to everyone who worked on this !!
Simon Peron@PeronLab7 Dec 2023
1/ How do somatotopically-matched regions of sensory cortex interact? In our most recent paper at @CellReports, @__laurenryan__shows that whisker S1-S2 amplify touch bidirectionally via a specialized population of broadly tuned touch cells. doi.org/10.1016/j.celrep.202…
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7/ When she targeted the C2 barrel in vS1, she found that it reduced touch responsiveness in vS2 in a whisker-specific manner.
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8/ Thus, a sparse population of multiwhisker cells amplifies touch responses across vS1-vS2 in a whisker-specific manner, showing that topographically matched regions of sensory cortical areas mutually amplify one another’s responses. Congratulations to Lauren and the team!
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Does scattering limit your in vivo imaging experiments? We 'super-resolve' neurons using the same trick how PALM/STORM microscopy resolves individual molecules (1/12).
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🚨#preprint alert 🚨 Happy to share new work from Kevin Ung, in collaboration with Per Nordmark! 🧵 on 👀👋🏻💉1/
bioRxiv Neuroscience@biorxiv_neursci30 Nov 2023
Acute loss of fingertip sensation leads to general compensatory changes in eye-hand coordination biorxiv.org/cgi/content/shor… #biorxiv_neursci
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🚨New paper alert from grad student @avmah44🚨 How do rats compute the value of their environment to guide their choices? nature.com/articles/s41467-0…

Distinct value computations support rapid sequential decisions

Nature Communications - How animals determine the value of the environment for motivation and error-based learning remains unclear. Here, the authors found that rats use multiple distinct...

nature.com
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