@ORSPF
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Postdoc @Trono_Lab & former PhD student in @Crougeulle Lab! interested in genome evolution 🤘🏼
Switzerland
Joined February 2012
- Tweets99
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- Likes478
Olga ROSSPOPOFF retweeted
I’m excited to share a new preprint from some of my work in the lab of @todd_macfarlan ! 😄
We dived into young KZFP gene clusters in different mouse strains and species to uncover mechanisms that facilitated their evolution and diversification in mice
Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice biorxiv.org/content/10.1101/… #biorxiv_genetic
Olga ROSSPOPOFF retweeted
Finally out! We present EXTRA-seq, a new EXTended Reporter Assay to quantify endogenous enhancer-promoter communication at kb scale!
biorxiv.org/content/10.1101/…
A 🧵about what it can do:
Olga ROSSPOPOFF retweeted
Find out how genome loci are anchored to the nucleolus!
Exciting preprint @Trono_Lab shows that ZNF274 competes with CTCF to keep H3K9me3 silenced genome at the nucleolus periphery, fine-tuning cell-specific gene expression.
preLight: @Silviacamoeira ⬇️
prelights.biologists.com/hig…
Olga ROSSPOPOFF retweeted
Le Dr Claire Rougeulle, @CRougeulle, est nommée directrice du Centre de recherche de l’@institut_curie. Sa nomination le 3 juillet 2024 par le Directoire de l'Institut Curie, marque le début d'un mandat de 5 ans.
➡️ curie.fr/actualite/instituti…
Olga ROSSPOPOFF retweeted
Happy to share the latest publication from the lab: XIST dampens X chromosome activity in a SPEN-dependent manner during early human development pubmed.ncbi.nlm.nih.gov/3883…
Congrats to @CharbelFeghaly @JeffOui94 @manucazottes @GribnauLab, David lab @ParisEpigenetix
Olga ROSSPOPOFF retweeted
Excited to share our effort to understand mechanisms underlying the potential for gastruloids self-organisation! #Gastruloids #InNumberWeTrust #EMT
biorxiv.org/content/10.1101/…
1/11
Olga ROSSPOPOFF retweeted
Our paper is now out! Cell damage regulates expression of lipid-modifying enzymes via alternative transcription. @SARSCoV2 exploits this to boost Spike #acylation #palmitoylation and generate more infectious #virions! @FS_Mesquita @AbramiLaurence
nature.com/articles/s41467-0…
Olga ROSSPOPOFF retweeted
How does the segmentation clock instruct cells to form a somite boundary? Read our new pre-print “Clock driven waves of Tbx6 expression prefigure somite boundaries”, by @Olivier_Venzin and colleagues, to find out.
biorxiv.org/content/10.1101/…
Summary thread below: 1/15
Olga ROSSPOPOFF retweeted
Check out our latest preprint:
XIST dampens X chromosome activity in a SPEN-dependent manner during early human development biorxiv.org/content/10.1101/…
Olga ROSSPOPOFF retweeted
Ten points for cool paper title
cell.com/trends/genetics/ful…
Olga ROSSPOPOFF retweeted
Check this out: #lncRNA genes may exert their function through distinct mechanisms in different species. Thanks @JeffOui94 @ORSPF @Huret_C and all for your efforts. Stimulating collaboration with @RuggGunnLab and @heard_lab
academic.oup.com/nar/advance…
Olga ROSSPOPOFF retweeted
SO HAPPY that this paper is finally out. Congrats to all involved (especially @ORSPF, @CRougeulle) for this career changing endeavour! After several attempts, I'm delighted that this has found a welcoming home in @NAR_Open (🙏 review process)
#lncRNA
1/
academic.oup.com/nar/advance…
Olga ROSSPOPOFF retweeted
Express delivery from the @jbloom_lab arrived today!
Thank you very much @khdcrawford for sharing your plasmids for #SARSCoV2 neutralization assays from your recent @biorxivpreprint with us - we really appreciate it!
biorxiv.org/content/10.1101/…
Let the pseudotyping begin...
Olga ROSSPOPOFF retweeted
Working from home has reached a whole new level! Steve Henikoff is superexcited running his experiments using the CUT&Tag@home setup (PC: Jorja Henikoff). If you want to set this up, here is the link to CUT&Tag@home protocol
protocols.io/view/cut-amp-ta…
Olga ROSSPOPOFF retweeted
1/3 We had this recent #bioRxiv preprint from @todd_macfarlan and @Trono_Lab at our first Zoom-JC: biorxiv.org/content/10.1101/…. Very interesting study! Highlights include: large-scale ChIP-seq analysis of young KRAB-ZFPs in mouse followed by megabase CRISPR-deletion of KZFP clusters.
Olga ROSSPOPOFF retweeted
Didier Trono, a professor at @EPFL_en ’s Laboratory of Virology and Genetics, answers some common questions about SARS CoV-2 and the disease it causes, #COVID19.
bit.ly/2ULMQt1
Olga ROSSPOPOFF retweeted
Day 1 of remote working due to #coronavirus.
Well done @EPFL_en for taking the right measures and sending everyone to work from home - I hope other institutions across Europe do the same!
Let's all work together and do our part to #FlattenTheCurve of #COVID19
Olga ROSSPOPOFF retweeted
The Trono Lab @epflSV finally joined Twitter!
Follow us to keep up-to-date with our latest research on #transposons and #KZFPs in development, cancer and disease.
Olga ROSSPOPOFF retweeted
We are pleased to release an expanded CRISPR Targets track for the hg38 assembly, showing DNA sequences targetable by CRISPR RNA guides over the entire human genome. genome.ucsc.edu/cgi-bin/hgTr…
Olga ROSSPOPOFF retweeted
A #postdoc position is available in my lab to unravel the mystery of #Xchromosome inactivation in primates. If you are interested in #Epigenetics, #stemcells, #noncodingRNA, #evolution, please apply!! And please RT