Accidental group leader in Cambridge. Inflammation, Immunology, IL-1, Vascular Biology, Cellular Senescence.

Cambridge, England
Joined March 2019
Murray Clarke Lab retweeted
CHIP—not just a chip off the ol’ block Paul R. Carter @PaulCarterology, Murray CH. Clarke @MurrayClarkeLab & team @Cambridge_Uni find common #CHIP mutations produce distinct sex-dependent effects on atherosclerosis and differentially affect macrophage cytokines and clonal expansion, arguing against a common mechanism across CHIP: doi.org/10.1172/jci.insight.… The images show atherosclerosis in male and female mice transplanted with 10% Tet2+/-.
1
9
888
Murray Clarke Lab retweeted
Looking for an Assistant Teaching Professor and Course Director of the MPhil in Translational Medical Research at Cambridge. The role is to run academic and research components of the MPhil, and develop teaching and scholarship @MedCambridge @CamBioCampus jobs.cam.ac.uk/job/51441/
1
5
4
991
🚨Job alert🚨 Research Associate (Fixed Term) to join @MurrayClarkeLab in the stunning @HLRI_Cambridge to study vascular inflammation, macrophages and cytokine IL-1. Funded for up to 3yrs by @TheBHF grant. Apply by 9 February: buff.ly/3PRmHWk @Cambridge_Uni
1
3
5
398
Want to come and help us deliver on our mission to improve cardiovascular and lung health worldwide? @HLRI_Cambridge are recruiting for multiple new team members at present. Why not take a look? 1/6
1
7
7
1,723
Murray Clarke Lab retweeted
Postdoc in single cell RNA-Sequencing and Functional Genomics in Cardiovascular Biology @Cambridge_Uni jobs.cam.ac.uk/job/48385/
9
8
1,247
Murray Clarke Lab retweeted
Interested in a 4-year PhD studying the genetics of BMI and comorbidities? Don't wait, apply for my @AstraZeneca-funded studentship w/ @MikeXiao_JIANG 🔗: jobs.cam.ac.uk/job/48333/ (due October 31)! @CAMBRIDGE_CEU @HLRI_Cambridge @Cambridgecardio @DPHPC @CambridgeATS
1
22
3
28
8,618
Murray Clarke Lab retweeted
We are pleased to announce our next speaker in the Cambridge Cardiovascular Seminar series - bit.ly/3KaopAl held @HLRI_Cambridge Please contact Jane if you would like to join remotely bit.ly/4bwhzk4
4
1
5
1,937
Murray Clarke Lab retweeted
Very happy to share our article showing that T follicular helper cells protect from atherosclerosis promoting IgM secretion by MZB cells! It was not an easy path!! I can’t be happier! Thank you#CVR @mallat_lab @cj_binder @LabMcnamara @Jmtarkin and all! academic.oup.com/cardiovascr…
9
10
1
56
4,307
Murray Clarke Lab retweeted
Happy New Year 2024! ..and a Happy New Job?! 🫁 Come work with us at @HLRI_Cambridge on an exciting new @The_MRC funded project looking at mechanisms of lung inflammation to help develop new therapies for airway diseases Grateful if you can RT - Thanks! jobs.cam.ac.uk/job/44539/
1
22
20
4,041
Murray Clarke Lab retweeted
Proving we can drag ourselves away from our facinating #research and have some festive fun 🎄😋😊
3
1
10
2,069
Murray Clarke Lab retweeted
Excited to share that our stem cell-based model for studying small vessel disease and vascular dementia has been published! A small step, but a crucial one, in addressing this important issue. #stemcells #vascularhealth @CamStroke @Cambridgecardio @HLRI_Cambridge @CamNeuro 1/5
5
18
1
65
9,136
Murray Clarke Lab retweeted
Happy to say I successfully defended my PhD thesis yesterday! Thank you to @MurrayClarkeLab and @harrisonpaulh for an interesting viva discussion. A huge thank you to Ed Rainger and @McGettrickLab for your support over the last few years. We did it! @MIDASUoB @ICVS_UoB
2
1
1
21
1,147
Murray Clarke Lab retweeted
VSMCs are efficient activators of IL-1β that do not use canonical inflammasomes or caspases. Hence, this alternative pathway could be targeted for long-term treatment of CVDs, as it is not central to everyday host defence @MurrayClarkeLab @society_eas 🔗atherosclerosis-journal.com/…
8
15
1,903
Just published by @GroupXuan @mallat_lab @ClareBryant13 @MurrayClarkeLab at #HLRI showing that drugs inhibiting PLK1 are of benefit in models of inflammatory disease characterised by excessive NLRP3 activation, such as heart failure & cardiac failure. jci.org/articles/view/162129
3
1
15
1,974
Murray Clarke Lab retweeted
Check our paper published at JCI, featured as cover for this issue. Brilliant team members (@m_baldri Christain Doreth Yang Li @DrEmilyFW …) and collaborators (@zxh1121 @MurrayClarkeLab @GdC_CCCB_lab @m_malumbres @ZMallat…) for this collective effort. Thanks to @TheBHF .
3
3
1
20
1,715
#Cover: PLK1 regulates NLRP3 inflammasome activation by controlling microtubule organization: buff.ly/3MmUEgj @GroupXuan @m_baldri @zxh1121 @DrEmilyFW @MurrayClarkeLab @GdC_CCCB_lab @m_malumbres @ZMallat #CellBiology #Immunology
1
9
29
3,438
🚨Seeking new team members! We're seeking an experienced Postdoctoral Research Associate to contribute to our work investigating the role of innate immune cells in acute inflammation. If this might be you, take a look at the link / DM me for more details: jobs.cam.ac.uk/job/43571/
1
36
28
8,286
Murray Clarke Lab retweeted
Thank you Jane @Beautifullight1 for sharing your wise scientific knowledge and your tips to survive in Academia. More than 30 yr of research #WomenInSTEM, 26 yr at @Cambridge_Uni @MedCambridge and 13 yr with @ZMallat . Also a mentor and a friend for us too! Great leaving do talk!
1
7
2
23
3,352
WANTED - an enthusiastic and experienced senior Operations Manager to help us deliver on our mission to improve cardiovascular and lung health across the globe: Victor Phillip Dahdaleh Heart & Lung Research Institute Operations Manager @Cambridge_Uni jobs.cam.ac.uk/job/42656/
9
1
13
7,869