Understand protein structure-function relationships and use this knowledge to answer fundamental questions of chemistry/biochemistry at the University of Otago.
Joined April 2020
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MatthiasFellner retweeted
Check out our latest covalent probes for imaging Staphylococcus aureus infections published @J_A_C_S. Great work from @JeyunJo and @TulsiUpadhyay5 and collaborators. pubs.acs.org/doi/full/10.102…
MatthiasFellner retweeted
Thrilled to share the news!! Thanks Matt @mbogyo, for giving this fantastic opportunity to work on this project. Enjoyed teaming up with @JeyunJo, @MFellnerLab and all our collaborators 🙌 Thanks @ec_woods, @NikkiPedowitz, @SijieWang5 for helping us with this project!!
Check out our latest covalent probes for imaging Staphylococcus aureus infections published @J_A_C_S. Great work from @JeyunJo and @TulsiUpadhyay5 and collaborators. pubs.acs.org/doi/full/10.102…
MatthiasFellner retweeted
Exciting news from our recent research with @TulsiUpadhyay5 on oxadiazolone-based probes targeting FphE, a S. areus specific serine hydrolase. This is a result of great collaboration with @MFellnerLab, the Valdez lab, Joanna Jaworek-Korjakowska, and the team at @mbogyo lab.
Looking for a new covalent electrophile for serine and cysteine nucleophiles? Check out this great work by @JeyunJo and @TulsiUpadhyay5 developing an oxadiazolone based probe for the S aureus serine hydrolase FphE. biorxiv.org/content/10.1101/…
MatthiasFellner retweeted
Looking for a new covalent electrophile for serine and cysteine nucleophiles? Check out this great work by @JeyunJo and @TulsiUpadhyay5 developing an oxadiazolone based probe for the S aureus serine hydrolase FphE. biorxiv.org/content/10.1101/…
MatthiasFellner retweeted
Bacterial biofilm therapeutics project wins Marsden Fund support ift.tt/Ylq0Vr9
A project investigating new ways to fight deadly bacterial biofilms has won a Marden Fast-Start fellowship for its lead researcher, Otago biochemist Dr Matthias Fellner.
Matthias is seeki…
MatthiasFellner retweeted
Otago researchers set to tackle health issues with Career Development Awards ift.tt/ED3hxJa
From a global health crisis to Aotearoa’s health inequity – University of Otago projects awarded Health Research Council funding will benefit those at home and around the world…
MatthiasFellner retweeted
$3.8 million to Otago researchers in Career Development Awards ift.tt/Zaz9o1D
The Health Research Council has awarded 19 Otago researchers almost $3.8 million in Career Development Awards.
These awards help launch research careers through a wide range of master’s and…
MatthiasFellner retweeted
Taputapu kē! Dr Matthias Fellner🧑🔬 @MFellnerLab @OtagoBiochemist @otago has been awarded a #MarsdenFund Fast-Start to study how #Staphylococcus aureus 🦠 use biofilms in antibiotic 💊 resistant bacteria #infection s🏥. #staph #AntibioticResistance
royalsociety.org.nz/what-we-…
MatthiasFellner retweeted
Really excited to have our paper describing mutations in histone H4 now out - a fantastic collaboration with @GijsvanHaaften and lots of families around the world. Now investigating the mechanism thanks to @MarsdenFund support!
New! Tessadori et al. demonstrate that de novo variants in histone H4 cause a neurodevelopmental disorder
bit.ly/3IgnevO
MatthiasFellner retweeted
Thanks also to @MacePeter for helping with the structural interpretations of these mutations within the nucleosome!
MatthiasFellner retweeted
@CeciMGLab has an open position for a postdoc to develop an environmentally friendly bacterial platform for the recovery of rare earth elements from complex E-waste. DM if interested, ad coming soon. @ARPAE
MatthiasFellner retweeted
JoLS #JournalofLifeSciences very first #Newsletter Doc Post is live journaloflifesciences.org/fi…
Huge boost to the initiative by ex-postdocs from #Harvard & #MIT! Our first-ever #PeerReviewed #OpenAccess global publication run entirely by #PostdocScientists.
Celebrate & Enjoy reading!
MatthiasFellner retweeted
As a cool followup I was also asked to prepare a 'Behind the Paper' post about the history of this work which turned into a history of my career in covalent probes. Check it out!
bioengineeringcommunity.natu…
MatthiasFellner retweeted
Want to visualize bacterial physiology or structure? Then try a chemical probe! Check out our new review in the 25th Anniversary Issue of @Molecules_MDPI. Thanks for your great work, co-authors @hirajonathan @Jalal_UiT and @mmhaugland!
mdpi.com/1420-3049/25/21/494…
MatthiasFellner retweeted
Our latest work is out ! We revealed novel enzymatic activities (α-hydroxyacid racemases and epimerases) in the nickel-pincer nucleotide (NPN) superfamily.
@SoumillionLab @MFellnerLab @CSB_UGent
nature.com/articles/s41598-0…
MatthiasFellner retweeted
@MFellnerLab et al. report on the molecular rationale for the design of probes/inhibitors for the S. aureus Fph family:
pubs.acs.org/doi/10.1021/acs…
MatthiasFellner retweeted
Excited to post our latest work collaborating with @ShabatGroup developing a chemiluminescent sensor of a Mycobacterium tuberculosis protease for rapid and inexpensive diagnosis, therapy monitoring and drug susceptibility testing. Great work @BrettMBabin biorxiv.org/cgi/content/shor…
MatthiasFellner retweeted
Very excited about the prospect of chemiluminescent probes for clinical applications. A great collaboration with @ShabatGroup. Many thanks to all the contributors: @gabyFercu, @AlvaroAOrdonez, @kellerlauraj, @JainLabHopkins, and others; and to @CarolynBertozzi for use of the BSL3
Excited to post our latest work collaborating with @ShabatGroup developing a chemiluminescent sensor of a Mycobacterium tuberculosis protease for rapid and inexpensive diagnosis, therapy monitoring and drug susceptibility testing. Great work @BrettMBabin biorxiv.org/cgi/content/shor…
MatthiasFellner retweeted
Hello @LatinXChem this is my group's work "Uncovering Rare Earth Elements Biochemistry: From enzymes to applications", #LatinXChemBio, BIO-003. #BIO-003
MatthiasFellner retweeted
Excited to share our latest publication from the PhD of Pavel Filipcik. We discovered that the MAP3K MEKK1 actually has a tubulin-binding domain of its own, providing a direct link to microtubule remodelling/stress. pnas.org/content/early/2020/…
