Scientist @Genentech. Previously: Postdoc @Stanford and PhD @Caltech. Chemical Biology, Mass Spectrometry, Biophysics. he/him
California, USA
Joined December 2011
- Tweets183
- Following708
- Followers310
- Likes1.2K
Brett Babin retweeted
Our latest paper is out at bioRxiv. Great work from @FrancoFaucher and collaboration with Alex Adibekian. biorxiv.org/content/10.1101/…
Brett Babin retweeted
Excited to share the first research paper from our team deposited on bioRxiv biorxiv.org/cgi/content/shor…. Our study harnesses a natural-product inspired electrophile for covalent protein modification. Led by amazing postbacs with tremendous help from proteomics core @NCIResearchCtr
Brett Babin retweeted
Our department has grown quite a bit over the last year. We have one group leader position remaining- Principal Scientist, Interactomics. If you are interested in developing and applying cutting edge proteomics research to therapeutic discovery apply here: careers.gene.com/us/en/job/G…
Brett Babin retweeted
My team has a postdoctoral position open at Genentech in Infectious Disease focused on the development and use of chemical biological approaches in microbiome research. If interested, please see: roche.wd3.myworkdayjobs.com/…
Open position in our biophysics group. A great opportunity to make an impact in small molecule drug discovery. No PhD required.
careers.gene.com/us/en/job/G…
@Chemjobber #chemjobs #biotech
Brett Babin retweeted
Congratulations to team Saki @hopeflaxman @Big_Fish_Linda @nandinivsr Hannah Dacheng and collaborators @MattRPratt and Binyou! This was a true collaborative effort in the group to discover a degron for cereblon! rdcu.be/cXTkl
Great opportunities for applying chemical biology to study the microbiome.
Interested in unraveling how the #microbiome modulates health and disease? Come join my new lab at @UniJena!
We have two #PhDpositions in #ChemicalBiology
Synthesis: bit.ly/3JEjIwT
Biochemistry: bit.ly/3BP7D5T
#chemjobs #chemPhD #ChemTwitter #microverse_exc 1/3
Brett Babin retweeted
So excited to finally be sharing this story!! Thank you to the many collaborators (including @taylorhnguyen in KC Huang's lab, the teams of @ajodonoghue, @MJNiphakis and Ami Bhatt, and my mentor @MLakeme) for helping me and @mbogyo bring this story to life!
Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. biorxiv.org/content/10.1101/…
Brett Babin retweeted
Our first paper on our efforts mapping serine hydrolases in gut commensal bacteria is out. We identified a homolog of the human DPP4 protease in B. theta that is important for community fitness. biorxiv.org/content/10.1101/…
Brett Babin retweeted
Excited to see this cryoEM of Pseudomonas aeruginosa RNAP! With my favourite regulator, SutA! Thanks to Yu Zhang, Yu Feng and colleagues for this very cool work.
nature.com/articles/s41467-0…
Brett Babin retweeted
Honored to see our work on ABPP-aided Mtb inhibitor discovery and characterization back to back with @mbogyo @BrettMBabin in excellent company in this special issue. Thanks, @CellChemBiol!
Open access: doi.org/10.1016/j.chembiol.2…
Now online, a focus issue on #Chemical #microbiology, highlighting chemical biology strategies to understand and manipulate host-pathogen interactions to enable development of new antiviral and antimicrobial therapies. hubs.li/Q01d4yKf0
Our #biophysics group at #Genentech is #hiring at the Sr/Principal Scientist level. Exciting opportunity to join a great group of colleagues working on challenging small molecule drug discovery projects.
Reach out if you have any questions about the role. careers.gene.com/us/en/job/G…
Great to see this published. Congrats @RockLabTB !
Excited to share our paper now out in @NatureMicrobiol nature.com/articles/s41564-0…. We used our CG screening and clinical Mtb genomics method to reveal novel mechanisms of drug resistance and identify a new opportunity to potentially use clarithromycin in TB treatment
Brett Babin retweeted
Excited to share our lab’s latest research article led by @FelipeB_dAndrea and @NickPoulton6, now on @ScienceAdvances. In this work we dissected the in vivo contributions of the essential caseinolytic protease subunits, ClpP1 and ClpP2, to M. #tuberculosis growth and pathogenesis
Brett Babin retweeted
Pls RT: I’m hiring! 🎉 Now opening a Scientist position (!) at Genentech to build 3D cultures of the TME.
Intended to provide industry exp for new PhDs/PDs that want to learn drug discovery. 1 yr contract.
Benefits:
-$120-130k salary
-health ins
-401K
-mentorship
#Postdoc position in our group at Genentech. This is a great group and a great environment for learning from our combined expertise in SPR, mass spectrometry, and other biophysical techniques. #postdocjobs Quinn Lab linkedin.com/jobs/view/30107…
Brett Babin retweeted
Some scientific illustrations become memes*, some turn into cultural icons.
It requires a combination of originality, aesthetic, simplicity and scientific accuracy.
Here are some of them 🧵
1/n
*memes in the original sense: units of cultural inheritance that replicate and evolve
ALT DNA double helix
ALT Waddington's landscape
ALT Vitruvian man
ALT Ebola virus
Brett Babin retweeted
Not many Keystone conferences have a strong chemical biology focus but this one does: keystonesymposia.org/confere…. Please retweet as I think it features a mix of #chembio and pharmaceutical speakers. #chemtwitter
Brett Babin retweeted
A jarring story on how the war in Ukraine affects our colleagues at @EnamineLtd and the @covid_moonshot efforts.
bloomberg.com/news/articles/…
Brett Babin retweeted
Check out the special issue of Biological Chemistry that I guest edited together with Claudia Jessen-Trefzer and that features eight exciting articles on "Chemical biology in drug discovery". You can find our editorial here: (1/11) doi.org/10.1515/hsz-2022-011…