Renzo Luisi - Professor of Organic Chemistry #Uniba, Flow Chemistry, Organolithium Chemistry, Fluorinated Molecules, Heterocyclic Chemistry, Nitrogen Transfer
Bari, Puglia
Joined May 2018
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Luisi-Lab retweeted
New paper out in Organic Letters! ๐
Polar and e-radical strain-release strategies provide modular access to C1- and C4-functionalized OBHOs from bicyclo[1.1.0]butane carboxylic acids.
A collaboration across Bari, Bologna & Sassari!
pubs.acs.org/orlef7/article-โฆ
Luisi-Lab retweeted
Super-strained spirocycles meet AI-supported target fishing. โน๏ธ๐ค๐ฃ
We introduce a new class of "super-strained" spirocycles which through AI-supported target fishing (@CASChemistry) were found to be agonists for the sigma-1 receptor. ๐
Now in @angew_chem
Link in comments๐
A novel and sustainable continuous-flow approach for atom deletion and insertion by electrophilic nitrogen transfer - now published in Green Chemistry pubs.rsc.org/en/content/artiโฆ
Luisi-Lab retweeted
If strained spiro heterocycles have caught your attention, wait until you meet their "super-strained" counterparts. Full disclosure of results soon - stay tuned!! ๐
@Luisi_Lab @SusPharma_eu
Luisi-Lab retweeted
๐ @Luisi_Lab is supporting applications for a MSCA Fellowship!
Join us to develop your own project with a strong focus on knowledge exchange in:
๐ฌ Flow chemistry | ๐ก Photochemistry | ๐ค AI-driven drug discovery
๐ Bari, Italy ๐โ๏ธ
๐ฉ Send your CV+project idea to @Luisi_Lab
Luisi-Lab retweeted
Excited to share our Chem. Soc. Rev. paper on greener-by-design fine chemicals! ๐ฑ๐ฑ
A joint effort by Italian, German, British, Slovenian & Belgian teams. Congrats to PhD student Jonas Wuyts (ORSY) & all co-authors! pubs.rsc.org/en/content/artiโฆ
Check out the front cover!
Luisi-Lab retweeted
๐ฌModular access to spiro[2.3]hexanes!
New sulfonium salts enable JCC-type reactions to build oxa- & diazaspiro[2.3]hexanes-rigid, spยณ-rich bioisosteres.
๐Supported by in silico prediction + in vitro validation by @Luisi_Lab - @angew_chem - Wiley Online Library onlinelibrary.wiley.com/doi/โฆ
Luisi-Lab retweeted
๐New Preprint: We report a radical disconnection strategy that enables the direct, single-step, photocatalytic conversion of ฮฑ-amino acids into differentiated vicinal diamines.
Broad scope, functional-group tolerant, and scalable in flow.
๐@ChemRxiv: chemrxiv.org/engage/chemrxivโฆ
Luisi-Lab retweeted
๐Interested in strained spirocycles as potential bioisosteres? ๐
Our recent @angew_chem describes our approach for the modular synthesis of spiro[2.3]hexanes and our in silico & in vitro investigation of their potential bioisosterism! @Luisi_Lab
onlinelibrary.wiley.com/doi/โฆ
Luisi-Lab retweeted
An interesting skeletal construction method published in Nature:
nature.com/articles/s41586-0โฆ A similar approach, published 75 years ago, still seems to be more convenient (although may be less tolerant): orgsyn.org/demo.aspx?prep=CVโฆ
Luisi-Lab retweeted
After 50 years, radical chemistry returns to Italy! ๐ฎ๐น
Bologna will host ๐๐ฆ๐ข๐๐ฅ-๐ญ๐ฐ (7โ10 Jun 26), the international symposium on free radicals
Cutting-edge science, world leaders, and unforgettable radical chemistry!
๐isofr14.it
#ISOFR14 #Chemistry #Radicals
Luisi-Lab retweeted
Just wrapped up JISOC2025 โ the JapaneseโItalian Symposium on Organic Chemistry ๐ฏ๐ต๐ค๐ฎ๐น
A huge honor to host outstanding Japanese and Italian scientists in Bari. Inspiring talks and posters all around!
Thanks to all participants and the amazing @Luisi_Lab team! @farmuniba
Luisi-Lab retweeted
โญ๏ธ๐๐ก๐ซ๐ข๐ฅ๐ฅ๐๐ ๐ญ๐จ ๐ฉ๐ซ๐๐ฌ๐๐ง๐ญ ๐ฆ๐ฒ ๐๐ข๐ซ๐ฌ๐ญ ๐ฉ๐จ๐ฌ๐ญ๐๐ซ at the ๐๐๐ฉ๐๐ง๐๐ฌ๐โ๐๐ญ๐๐ฅ๐ข๐๐ง ๐๐ฒ๐ฆ๐ฉ๐จ๐ฌ๐ข๐ฎ๐ฆ ๐จ๐ง ๐๐ซ๐ ๐๐ง๐ข๐ ๐๐ก๐๐ฆ๐ข๐ฌ๐ญ๐ซ๐ฒ, and even more honored that it was awarded the ๐๐๐ฌ๐ญ ๐๐จ๐ฌ๐ญ๐๐ซ ๐๐ซ๐ข๐ณ๐!๐
@NathoPhilipp @JisocSymposium @Luisi_Lab
Luisi-Lab retweeted
It was very inspiring to attend the presentations given by such distinguished guest speakers at #JISOC2025: Prof. Keiji Maruoka (Kyoto University); Prof. Luisa De Cola (University of Milan); Prof. Yoshiaki Nishibayashi (Tokyo University) - part 1
@Luisi_Lab โ at Bari, Apulia
Luisi-Lab retweeted
It was very inspiring to attend the presentations given by such distinguished guest speakers at #JISOC2025: Prof. Gianluca Farinola (University of Bari); Prof. Motomu Kanai (Tokyo University); Prof. Francesca Paradisi (University of Bern) - part 2
@Luisi_Lab โ at Bari, Apulia
Luisi-Lab retweeted
It is a great honour that Prof. Mikiko Sodeoka is the first speaker at JISOC 2025, showing us the past, present and future prospects in late transition metal enolate chemistry!
#JISOC2025 @Luisi_Lab โ at Bari, Apulia
Luisi-Lab retweeted
Italy and Japan finally together: JISOC 2025 has begun in Bari! Prof. Renzo Luisi, Prof. Paolo Melchiorre, Prof. Gianluca Maria Farinola and Prof. Keiji Maruoka opened this unique event. @Luisi_Lab @SCIorganica โ at Bari, Apulia
Luisi-Lab retweeted
Congrats to Shijin, Drew, and Martin on publication of this C-H arylation with remarkable terminal selectivity! 3,5-lutidine turns out to be key! Check it out @ChemEurJ
chemistry-europe.onlinelibraโฆ
Iodonitrene-Mediated Nitrogen Transfer to Alkenes for the Direct Synthesis of NH-Aziridines | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jacโฆ
