@JamesRuFletcher

ageing, health, disability, cognition, digitalisation, infrastructure, connection

 Bath
scholar.google.com/citations?user=Qg80LqMAAAAJ&hl=en
Joined October 2015
  • Tweets3K
  • Following504
  • Followers875
208Media
James Rupert Fletcher retweeted
Robert Howard@ProfRobHowardJul 2
Our new OA paper explains what should convince a clinician of disease modification in Alzheimer's clinical trials and appraises what trials so far really show. TLDR - data as presented don’t convincingly support disease modification. alz-journals.onlinelibrary.w…

What should convince a clinician of disease modification in Alzheimer's disease clinical trials?

The recent publication of extension data from post-regulatory trials of amyloid-lowering antibody therapies, such as donanemab and lecanemab, requires clinicians to critically appraise trial designs...

alz-journals.onlinelibrary.wiley.com
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@DementiaUK @alzheimerssoc @AlzResearchUK @alzassociation @mariecurieuk @DorothyHouseHC @access2care @PEoLCSW @TheAPPMuk @kingsnmpc
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James Rupert Fletcher retweeted
UoM School of Social Sciences@uomsoss5 Nov 2024
🎬 See films made with local older people, including @rxtheatre Elders & explore urban life through different eyes. Followed by friendly Q&A! @anthonyburgess on Nov 6th, 2pm. Friendly atmosphere, great conversation. Book: [eventbrite.co.uk/e/mancheste…] #McrESRCFest #ESRCFestival
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James Rupert Fletcher retweeted
AWARD Network@AWARD_UCSF30 Oct 2024
The AWARD Network November webinar is next week! Wednesday, November 6, 9-10am PT “Utilizing VR and Robotics in Dementia" awardnetwork.ucsf.edu
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James Rupert Fletcher retweeted
UoM School of Social Sciences@uomsoss31 Oct 2024
📽️ Discover what it means to be part of the ageing urban community! Join us @anthonyburgess, 6 Nov, 2pm to explore films about life in Manchester as we age. Free entry, part of @ESRC. In collab with @MUARG1 eventbrite.co.uk/e/mancheste… #McrESRCFest #ESRCFestival
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James Rupert Fletcher retweeted
NICE
@NICEComms23 Oct 2024
Donanemab is not recommended by NICE for cognitive impairment or dementia caused by Alzheimer's. This is due to limited benefits and high costs, including monthly infusions and intensive side effect monitoring, therefore it not good use for the taxpayer: nice.org.uk/news/articles/ne…
Graphic showing photo of healthcare professional looking at brain scans and the following text: New Alzheimer's treatment donanemab does not currently demonstrate value for the NHS.

ALT Graphic showing photo of healthcare professional looking at brain scans and the following text: New Alzheimer's treatment donanemab does not currently demonstrate value for the NHS.

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James Rupert Fletcher retweeted
Ash Paul
@pash2218 Oct 2024
Replying to @pash22 @LogarithmicDis @MemoryDoc @LonSchneiderMD @AlbertoEspay @nvillain_alz @seb_walsh @EWidera @LTCShop @PAULJLAMONT @ProfRobHoward @MadhavThambiset @RenegadeSynapse @dr_shibley @PhilAlz @_michael_scholl @VincentPlanche @Gill_Livingston @DrTFromKC @JamesRuFletcher @AdamMBrickman @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @DrJoRyan @MaggieAime @DavidJonesBrain @PTenigma @adamhdyer @DrewQJoseph @jocelynkaiser @jmschott @ayton_scott @Kariem_Ezzat @jesse_brodkin
@EisaiUS to ask Australia's @TGAgovau to reconsider rejection of Alzheimer's drug Leqembi endpts.com/australia-rejects… via @KatherineMLewin

Eisai to ask Australia to reconsider rejection of Alzheimer's drug Leqembi

Australia’s regulatory agency rejected Biogen and Eisai’s Alzheimer’s drug Leqembi, noting that the drug's efficacy doesn't outweigh the safety risks. Australia's Therapeutic Goods Administration...

endpoints.news
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⬇️only two more weeks for submissions⬇️ @isa_sociology @SocioFamilyISA
James Rupert Fletcher@JamesRuFletcher7 Aug 2024
Working on 𝐌𝐎𝐁𝐈𝐋𝐈𝐓𝐈𝐄𝐒, 𝐂𝐋𝐈𝐌𝐀𝐓𝐄, 𝐅𝐀𝐌𝐈𝐋𝐈𝐄𝐒? Submit for “Connecting Mobility Ecologies, Climate Crises and Families” @isa_sociology conference 🇲🇦Rabat, Jul 6-11, 2025🇲🇦 ⏰300 word English abstracts due Oct 15⏰ isaconf.confex.com/isaconf/f…
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James Rupert Fletcher retweeted
Andrew Lees@ajlees26 Sep 2024
Concerning because this work has been used to support the alpha synuclein biological definition and the value of the seed assay @pash22 Did a top NIH official manipulate Alzheimer's and Parkinson’s studies for decades? | Science | AAAS science.org/content/article/…

Did a top NIH official manipulate Alzheimer’s and Parkinson’s studies for decades?

Agency announces research misconduct finding for neuroscientist Eliezer Masliah as scores of his papers fall under suspicion

science.org
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The 1st IN-CITU paper is Open Access @socscimed Guided by passengers with dementia on Manchester's re-municipalising bus network We go shopping👜 We pet dogs🐕 We navigate time, disability, inequality & segregation🏙️ sciencedirect.com/science/ar… @MCRSociology @morgancentre @MUARG1
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James Rupert Fletcher retweeted
Ash Paul
@pash2226 Sep 2024
Replying to @pash22 @LogarithmicDis @AlbertoEspay @nvillain_alz @seb_walsh @EWidera @MemoryDoc @LTCShop @PAULJLAMONT @LonSchneiderMD @ProfRobHoward @MadhavThambiset @RenegadeSynapse @dr_shibley @PhilAlz @_michael_scholl @VincentPlanche @Gill_Livingston @DrTFromKC @JamesRuFletcher @AdamMBrickman @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @DrJoRyan @MaggieAime @DavidJonesBrain @PTenigma @adamhdyer @DrewQJoseph @jocelynkaiser @jmschott @ayton_scott @Kariem_Ezzat @AE_MD @SpichakSimon
This is not new news from @US_FDA , this has been going on for donkey's ears "Financial conflicts of interest at FDA Drug Advisory Committee meetings" drive.google.com/file/d/1-DZ… via @VPrasadMDMPH et al
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James Rupert Fletcher retweeted
James Rupert Fletcher@JamesRuFletcher7 Aug 2024
Working on 𝐌𝐎𝐁𝐈𝐋𝐈𝐓𝐈𝐄𝐒, 𝐂𝐋𝐈𝐌𝐀𝐓𝐄, 𝐅𝐀𝐌𝐈𝐋𝐈𝐄𝐒? Submit for “Connecting Mobility Ecologies, Climate Crises and Families” @isa_sociology conference 🇲🇦Rabat, Jul 6-11, 2025🇲🇦 ⏰300 word English abstracts due Oct 15⏰ isaconf.confex.com/isaconf/f…
ISA@isa_sociology6 Aug 2024
📣 #ISAforum25 Call for Abstracts is now open! Review the guidelines and prepare your submission here 🌐 isa-sociology.org/en/confere… ⏰ October 15, 2024 is the final date to submit your abstract. No extensions to the deadline will be provided.
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A little late to the #WAD party but if you scroll deep down in the World Alzheimer Report 2024 you'll find a more critical stance👇 (QT because I can't reply to you for some reason!) alzint.org/resource/world-al…
Shibley@dr_shibley23 Sep 2024
Replying to @ProfRobHoward
This has been a known issue for some time - see work of @JamesRuFletcher - that, as James described, corporate charities raise awareness for themselves by blaming a lack of awareness about dementia, which they also say is responsible for stigma.
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Always love an @WankaAnna workshop✂️📸 So much great digital ageing work (& fun) @ socio-gerontechnology 2024 @socgerontech @MattLariv @wendymartin007 @juliane_jarke – at Vienna, Austria
Stephanie Hatzifilalithis, PhD@Stephaniehatzi20 Sep 2024
Excited to be at the @socgerontech conference in Vienna 🌞 Great morning spent workshopping and visualizing the relationality of age(ing) and technology 🤖
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James Rupert Fletcher retweeted
Prof June Andrews@ProfJuneAndrews14 Sep 2024
‘The data on extreme human ageing is rotten from the inside out’ – Saul Justin Newman. Best morning read. theconversation.com/the-data…
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A story in two parts.. Loving my first week at @BathSofM @ido_bath & pleased to report the rain has followed me south🌦️
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Frustrating morning of radio coverage based entirely on charity talking heads, disappointment and "hope" Haven't heard anything about the drug, its risks/benefits or cost implications
Ash Paul
@pash2223 Aug 2024
Replying to @pash22 @LonSchneiderMD @DanClintonRN @LogarithmicDis @nvillain_alz @seb_walsh @smead2 @EWidera @MemoryDoc @LTCShop @PAULJLAMONT @ProfRobHoward @MadhavThambiset @RenegadeSynapse @dr_shibley @AlbertoEspay @PhilAlz @_michael_scholl @vincentplanche @Gill_Livingston @DrTFromKC @JamesRuFletcher @AdamMBrickman @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @PharmRJ @DrJoRyan @MaggieAime @alzassociation @HAS_sante @MayoClinic @DavidJonesBrain @KeckMedicineUSC @DrK_W1984 @dmrind
Debate rages over Alzheimer’s drug lecanemab as UK's @NICEComms limits approval: The medicine is being assessed by agencies including the European Union regulator, but the community is divided on its efficacy and safety. nature.com/articles/d41586-0… via @DianaMKwon

Debate rages over Alzheimer’s drug lecanemab as UK limits approval

Nature - The medicine is being assessed by agencies including the European Union regulator, but the community is divided on its efficacy and safety.

nature.com
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James Rupert Fletcher retweeted
Ash Paul
@pash2222 Aug 2024
Replying to @pash22 @DanClintonRN @LogarithmicDis @nvillain_alz @seb_walsh @smead2 @EWidera @MemoryDoc @LTCShop @PAULJLAMONT @LonSchneiderMD @ProfRobHoward @MadhavThambiset @RenegadeSynapse @dr_shibley @AlbertoEspay @PhilAlz @_michael_scholl @VincentPlanche @Gill_Livingston @DrTFromKC @JamesRuFletcher @AdamMBrickman @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @DrJoRyan @MaggieAime @DavidJonesBrain @PTenigma @adamhdyer
@NHSEngland & @WGHealthandCare 's cost-effectiveness agency @NICEComms gives negative review of Alzheimer’s drug Leqembi: The treatment from Eisai and Biogen has hit another roadblock in reaching patients in Europe statnews.com/2024/08/22/uk-l… via @DrewQJoseph

U.K.'s cost-effectiveness agency gives negative review of Alzheimer's drug Leqembi

Leqembi, the Alzheimer’s treatment from Eisai and Biogen, has hit another roadblock in reaching patients in Europe. 

statnews.com
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James Rupert Fletcher retweeted
Ash Paul
@pash2222 Aug 2024
Replying to @DanClintonRN @LogarithmicDis @nvillain_alz @seb_walsh @smead2 @EWidera @MemoryDoc @LTCShop @PAULJLAMONT @LonSchneiderMD @ProfRobHoward @MadhavThambiset @RenegadeSynapse @dr_shibley @AlbertoEspay @PhilAlz @_michael_scholl @VincentPlanche @Gill_Livingston @DrTFromKC @JamesRuFletcher @AdamMBrickman @SFAckley @howard_gleckman @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @EmmyBetz @PharmRJ @DrJoRyan @MaggieAime @alzassociation @HAS_sante @MayoClinic @DavidJonesBrain @KeckMedicineUSC @DrK_W1984 @sanilrege @PTenigma
Eisai said in its own release that it is working with NICE, the Scottish Medicines Consortium and the NHS to make Leqembi available “as soon as possible.” endpts.com/biogen-eisais-leq… via @Ayisha_Sharma97
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Working on 𝐌𝐎𝐁𝐈𝐋𝐈𝐓𝐈𝐄𝐒, 𝐂𝐋𝐈𝐌𝐀𝐓𝐄, 𝐅𝐀𝐌𝐈𝐋𝐈𝐄𝐒? Submit for “Connecting Mobility Ecologies, Climate Crises and Families” @isa_sociology conference 🇲🇦Rabat, Jul 6-11, 2025🇲🇦 ⏰300 word English abstracts due Oct 15⏰ isaconf.confex.com/isaconf/f…
ISA@isa_sociology6 Aug 2024
📣 #ISAforum25 Call for Abstracts is now open! Review the guidelines and prepare your submission here 🌐 isa-sociology.org/en/confere… ⏰ October 15, 2024 is the final date to submit your abstract. No extensions to the deadline will be provided.
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