@GoetzJacky

Cancer and Cell biologist🦀, CLEMist🔬, fan of #mechanobiology, #metastasis, #extracellularvesicles, #imaging. Amateur triathlete🚴‍♂️🏊👟.

 Strasbourg, France
goetzlab.fr
Joined September 2014
  • Tweets8.3K
  • Following1.1K
  • Followers3.4K
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💥 Pub.alert : check out our latest review article with @Tang_Lab_EPFL published @NatureNano today 🤩 📖 We discuss the implications of biomechanically regulated #immunosurveillance in #cancer and other diseases rdcu.be/dxdQ2 🧵 (1/n)
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I am confused - is (part of) the community still here 🐦 and not there 🦋 ?
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Very warm congratulations Jochen !
Max Planck Institute for the Science of Light@MPI_Light22 Oct 2024
Understanding the physics of cancer, preventing metastases: Jochen Guck (@GuckLab) receives the @Leopoldina Greve Prize 👏 The ability to explain the conditions that lead to cancer metastases is key to developing new approaches to cancer treatment. 👉 bit.ly/MPL-Guck-Greve-Prize
📸 © Markus Scholz / Leopoldina

ALT 📸 © Markus Scholz / Leopoldina

📸 © Stephan Spangenberg

ALT 📸 © Stephan Spangenberg

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Thank you @J_Cell_Sci ☺️ and please join us on 🦋
J Cell Science@J_Cell_Sci25 Nov 2024
Amandine Dupas, @GoetzJacky and @NaelOsmani @Inserm @CRBS_Strasbourg summarise the common and divergent mechanisms of endothelial responses during extravasation of leukocytes and CTCs. journals.biologists.com/jcs/…
Diagram showing mechanisms of extravasation, highlighting similarities and differences between CTCs and leukocytes. Circulating immune and cancer cells exit the vascular environment by crossing the endothelial barrier. The transmigration cascade occurs in a series of consecutive steps, which share similarities (green boxes) and discrepancies (orange boxes) depending on whether immune cells or cancer cells are extravasating.

ALT Diagram showing mechanisms of extravasation, highlighting similarities and differences between CTCs and leukocytes. Circulating immune and cancer cells exit the vascular environment by crossing the endothelial barrier. The transmigration cascade occurs in a series of consecutive steps, which share similarities (green boxes) and discrepancies (orange boxes) depending on whether immune cells or cancer cells are extravasating.

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Amandine Dupas, @GoetzJacky and @NaelOsmani @Inserm @CRBS_Strasbourg summarise the common and divergent mechanisms of endothelial responses during extravasation of leukocytes and CTCs. journals.biologists.com/jcs/…
Diagram showing mechanisms of extravasation, highlighting similarities and differences between CTCs and leukocytes. Circulating immune and cancer cells exit the vascular environment by crossing the endothelial barrier. The transmigration cascade occurs in a series of consecutive steps, which share similarities (green boxes) and discrepancies (orange boxes) depending on whether immune cells or cancer cells are extravasating.

ALT Diagram showing mechanisms of extravasation, highlighting similarities and differences between CTCs and leukocytes. Circulating immune and cancer cells exit the vascular environment by crossing the endothelial barrier. The transmigration cascade occurs in a series of consecutive steps, which share similarities (green boxes) and discrepancies (orange boxes) depending on whether immune cells or cancer cells are extravasating.

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First step, now find people 🤣 #lostinablueskydesert
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#job #alert we are looking for a #research #engineer to work on #organoids #organonchip development to model the #leukemia microenvironment Come and join our international #passarolab 🌍 to enjoy #multidisciplinary #science ⚗️🧫🧬🧪🩻 in the beautiful Paris 🥐🍷🫕 Please RT 🙏
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A treat ! & featuring our very own Cristina Liboni 🤩 You can’t miss that !
Andrés Hidalgo@AndrsHidalgo1615 Nov 2024
Interested in Cancer and Ageing? Last days to register!! 👇👇👇
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In this article, we summarize the common and divergent mechanisms of #endothelial responses during #extravasation of #leukocytes (in inflammation) and #CTCs (in #metastasis). We further highlight how these might be leveraged in the development of anti-metastatic #treatments.
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Funding of the related work : @Inserm @Université de Strasbourg @FondationARC @laliguecancer @RubanRose @Institut_cancer
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🔔 New publication alert : have you ever wondered whether #immune and #tumor cells use similar mechanisms to #extravasate ? Do they indoctrinate the #endothelium ? We did. Awesome work by Amandine & @NaelOsmani. Check it out : lnkd.in/dkHb4UAB Published in @J_Cell_Sci
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Check out our recently-updated preprint where we dig further in the #vascular contribution to #metastatic #extravasation. #Blood vessels aren't passive barriers : they react & help, when indoctrinated. Awesome updated work by Amandine supervised by @NaelOsmani #zebrafish
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The latest Ph.D. of the lab is born, and what a day 🍾! Congrats to @VMittelheisser for this amazing journey and to our sharp & constructive jury @hps2002 Sylvie Fournel Lucie Sancey Emmanuel Donnadieu, and to @AlxDetappe for the co-supervision.
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Opening the meeting of the French Society for #ExtracellularVesicles #FSEV2024 in #Strasbourg: @Neri_lab @HyenneV and the Young Network of #FSEV
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Awesome first afternoon at the annual FSEV @French_Soc_EVs meeting and a great talk by our post-doc Kuang-Jing 🤩 Great organization by FSEV, with our EV master @HyenneV à la baguette !
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Happening tomorrow in our beloved city of #Strasbourg !
FrenchSocEVs@French_Soc_EVs3 Oct 2024
linkedin.com/posts/french-so…

#extracellularvesicles #health #innovation #disease #drugs #biomarkers #training #careerpath...

THE FULL AND FINAL PROGRAM OF FSEV2024 IS OUT! CHECK IT OUT AT https://lnkd.in/d-KUPEB8 Our community is growing and getting more connected. 2024 and 2025 will be pivotal years for the FSEV, with...

linkedin.com
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We were very lucky to host @EloiseGrasset for almost 2 days in our lab @CRBS_Strasbourg and exchange on common interests with regards to metastatic progression of TNBC. Thank you Eloïse for a great seminar & thanks to @NaelOsmani for organizing that.
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Preprints: Embryogenesis @PauliGroup @CaloLabMIT @Arish__Shah (Dual ribosomal system/ Embryogenesis) biorxiv.org/content/10.1101/… @yinan_wan (transcriptomics/ gastrulation/ organogenesis) biorxiv.org/content/10.1101/… @AliceGodden @SimoneImmler (bioinformatics/ small RNA/ transposable elements) biorxiv.org/content/10.1101/… Nervous System @USC @gVallortigara (number sense; neural circuits; machine learning; ethanol) biorxiv.org/content/10.1101/… @meganydennis (autism/ risk gene/ megalencephaly) medrxiv.org/content/10.1101/… @CharlieDowell4 (Saccades/ neural activity) biorxiv.org/content/10.1101/… @annaostenrath @yaksi_emre (glutamate-driven inhibition/ neural circuit connectivity/ adaptive behaviors) biorxiv.org/content/10.1101/… @meganydennis (microglia/ cross-species analysis/ development) biorxiv.org/content/10.1101/… @meganydennis (neurological traits/telomere-telomere human genome sequence) biorxiv.org/content/10.1101/… @CalcNeuro (olfactory system/ adaptation/ stimulation) biorxiv.org/content/10.1101/… @T___Kawashima @zq_wei (serotonin/ neuromodulation/ circuit computations) biorxiv.org/content/10.1101/… @T___Kawashima (serotonin/ neuromodulation/ motor adaptation) biorxiv.org/content/10.1101/… @penghuang031 (BMP signaling/ Sclerotome/ Lineage) biorxiv.org/content/10.1101/… Regeneration @Savita_Gupta7 @rmarinjuez (heart regeneration/ glycoprotein/ fibrotic response) biorxiv.org/content/10.1101/… @DrIsaacWang @rmarinjuez (heart regeneration/ endothelial activity/ fibrotic response) biorxiv.org/content/10.1101/… @errricpeterman @jraslab (immune cells/calcium signaling/Langerhans cells) biorxiv.org/content/10.1101/… Behavior @GabrielBosse1 (development/ sensorimotor response/ behavioral characterization) biorxiv.org/content/10.1101/… @daniobrain (locomotion analysis/ neuroscience/ quantification sensorimotor transformations) biorxiv.org/content/10.1101/… #BaierLab @MPIforBI @IShainer @JohannesKappel (neuronal transcriptional profile/ visual responses/ morphology) biorxiv.org/content/10.1101/… @tal_lab (chemical toxicity/nervous system/behavioral phenotyping) biorxiv.org/content/10.1101/… Cancer @leonard_zon @chloe_s_brn (tumorigenesis/ leukemia/ treatment) biorxiv.org/content/10.1101/… @GoetzJacky @KatkaJerabkova (Lysosomal positioning/ Invasion/ Melanoma) biorxiv.org/content/10.1101/… @leonard_zon @aya_ludin (Melanoma/ Tumor-immune interactions) biorxiv.org/content/10.1101/… Heart & Muscle @TalbotLabMaine (Myofibril assembly/ Fast-twitch muscle/ Mylpf) biorxiv.org/content/10.1101/… @chrmosimann @hannah_moran (Pericardium/ Heart development) biorxiv.org/content/10.1101/… Vasculature @NorthTrista @EllieMeader (Mitophagy/ Hematopoiesis/ Bnip3lb) biorxiv.org/content/10.1101/… @Doulatov_lab (Hematopoietic stem cells/single cell dynamics/EHT) biorxiv.org/content/10.1101/… @NatashaOBrown1 (Blood-brain barrier/ Glia-vascular interactions) biorxiv.org/content/10.1101/… Evolution @craig_albertson @TomDoesScience @Pterycombus (Pectoral fin/ Cichlids/ Plasticity) biorxiv.org/content/10.1101/… Cell Biology @penghuang031 (Pdgfab/Pdgfra/ Chemoattraction/ Migration) biorxiv.org/content/10.1101/… @rita_d_mateus (purine crystals/vertebrate biocrystallization processes) biorxiv.org/content/10.1101/… @neurosandwich (Cadherin 16/ Corpuscle of Stannius/ Calcium homeostasis) biorxiv.org/content/10.1101/… Fin! 4 of 4
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Oyé oyé Strasbourg peeps - have a look at this exciting symposium with local, national andf internationol experts in we are organizing on November 7th and don't miss it ! Don't hesitate to diffuse & tell your neighbors, reach out (if you need info) or simply join.
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Had fun today explaining our research to a panel of heartful and generous souls #breastcancerawareness #octobrerose #CharityTuesday @InsermEst
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