Postdoc studying RNA biology, functional genomics, biochemistry, gene expression.
Denver, CO
Joined September 2018
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Laxman Gangwani: SMN knockdown causes dsDNA breaks?! And activation of DNA damage response pathways. Implications for high sensitivity of terminally differentiated motor neurons to SMN loss. #annualsmaconference #CureSMA
A great session at #annualsmaconference. Reduced mitochondrial transport in SMA motor neurons. Wonder if there's a link there to translation defects at the ER-mito connections? #curesma
Thanks so much for the opportunity to work on such an important problem. Does subcellular RNA localization become disrupted in SMA? If so, does this contribute to motor neuron disfunction? Hopefully these experiments will help answer these questions.
#CureSMA is pleased to announce the second 2019 recipient of the Audrey Lewis Young Investigator Award, Krysta Engel, PhD, at the University of Colorado.
To learn about Dr. Engel's project, visit:
curesma.org/news/engel-grant…
ALT Dr. Engel's picture
krystaengel retweeted
AveXis, a @Novartis company, recently announced interim data from ongoing trials of the investigational product Zolgensma® (AVXS-101) that showed positive results across a broad spectrum of patients with spinal muscular atrophy (SMA).
Learn more:
curesma.org/news/avexis-aan-…
ALT AveXis logo
krystaengel retweeted
Figuring out where RNAs are within cells and quantifying them can be tricky. Improved methods are being continuously developed to meet this challenge. Check out this review I wrote that summarizes classical and new techniques to study RNA localization. bit.ly/2LkO2BV
Oh man...really hits you in the feels! Won't give any spoilers but, oof!! What a bunch of story arcs! 💕💔
What Suja and I are wanting to learn more about is how universities get the word out about how they support the mental health of their staff at all levels. As a postdoc, it seems like gaining awareness of these services is not as straight forward as when I was a grad student.
krystaengel retweeted
Our lab is looking to add two positions to our team:
1) Postdoctoral scholar
2) Bioinformatician
PLEASE RT and help spread the word!
Applicants please email me directly at [email protected].
Thank you!
krystaengel retweeted
Just under a month left to register for this course. Excited to be a new instructor this year with @adelmanlab and @MarcMendillo!
Cold Spring Harbor Meetings and Courses - Long Island, New York. Scientific Conferences and Courses For Research and Education meetings.cshl.edu/courses.as…
Another covert? Nice work @chad_petit
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When I was in undergrad I named my cat Nero, then in grad school worked on the trigger loop! Life is weird. Also this quote, "where it inhibits an enzyme responsible for protein synthesis; without protein, the cells begin to die" 😕
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krystaengel retweeted
Three weeks left to apply for our summer internship program for undergrads!
Please RT: Our excellent paid Summer Internship Program for undergrads is accepting applicants for 2019!
Deadline to apply is Feb. 15, 2019.
rnabio.co/summer-interns
krystaengel retweeted
SUPER PROUD (and in awe of) @EngelKrysta for receiving a postdoctoral fellowship from @CureSMA. I have no doubt her work on how SMN regulates RNA localization will advance our understanding of SMA. Thanks @CureSMA! – at Colorado, USA
krystaengel retweeted
TONS of RNA localization datasets (including ours) have seen mRNAs encoding ribosomal proteins enriched in neuronal projections. Why would that be? Aren't ribosomes assembled in the nucleolus? Finally, an explanation for this bizarre observation!
biorxiv.org/content/biorxiv/…
krystaengel retweeted
The BMG department @CUAnschutz is looking for a new chair: cu.taleo.net/careersection/2…
Please consider applying and spread the word!
The incoming chair will lead a wonderful group of biochemists, molecular biologists (@molbcu), RNA (@rnabioco) and structure folks among others!
krystaengel retweeted
REPLACE ME! After 25 years, I'm stepping down as Director of CCAM. But not retiring - looking forward to more time for my research and teaching. @graveley chairs search committee for a multidisciplinary cell biophysics leader. Apply to @uconnhealth here:
jobs.uchc.edu/
