@MarcMendillo

Assoc. Prof, Biochem & Mol Genetics, @NUFeinbergMed, Full Member @LurieCancer

 Chicago, IL
mendillolab.org
Joined February 2014
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  • Following734
  • Followers565
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Very happy to share our latest paper – terrific work by Milad Alasady in @PNASNews An HSF1–JMJD6–HSP feedback circuit promotes cell adaptation to proteotoxic stress | PNAS pnas.org/doi/10.1073/pnas.23…
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Replying to @MarcMendillo @PNASNews
Thank you to all other contributors: @SeeshaTakagishi , @DavidAmici4 , @Roger5mith , Dan Ansel, @EBartom , along with Dmitri Segal working with @mike_tilapia, and Martina Koeva working with Luke Whitesell and Susan Lindquist - who I miss very much
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Happy to share our latest HAPSTR1 paper revealing novel factors in the HAPSTR1/HUWE1 axis & demonstrating its essential role in mammalian life. Terrific work by @DavidAmici4 with important contributions from Sammy Alhayek @LSAjournal doi.org/10.26508/lsa.2023023…
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Additional contributions from @PrezKlein, Milad Alasady, McKenzi King, and our great collaborators Yi-Zhi Wang, Anika P Wilen, Weimin Song, Pei Zhu, Abhishek Thakkar, Adam Steffeck, @clara_peek & @savas_lab
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And big thank you to @ACS_Research @aboa_chicago @theNCI for support!
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The recently discovered HAPSTR1 protein facilitates a nuclear quality control pathway essential for mammalian life @MarcMendillo @DavidAmici4 @NU_BSA @NU_BMG_SQE @NUMSTP life-science-alliance.org/co…
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Delighted to announce, for his fundamental discoveries with broad impact on biochemistry, biology & medicine, Dr. Craig Crews @CraigMCrews is the 2024 recipient of the #KimberlyPrize in Biochemistry and Molecular Genetics awarded by SQE @NUFeinbergMed bit.ly/47JFnyT

Pioneering Biochemist Craig Crews Named Winner of 2024 Kimberly Prize - News Center

Northwestern University Feinberg School of Medicine and the Simpson Querrey Institute for Epigenetics announced today that renowned biochemist Craig M. Crews, PhD, who pioneered the pharmaceutical...

news.feinberg.northwestern.edu
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What are the genes most essential for stressed cancer cell growth -exciting talk by Marc Mendillo @MarcMendillo lab! #CSSI #HSF1 #stress
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🔦Spotlight on Lv et al in @ScienceMagazine: Addicted to proteostasis: How KRAS-driven cancers acquire resistance to clinical KRAS inhibitors by Austin T. Klein and @MarcMendillo at @NUFeinbergMed @LurieCancer dlvr.it/SyzBJG
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Looking forward to this!
Northwestern BMG and SQE@NU_BMG_SQE26 Apr 2023
Join us tomorrow for the BMG Seminar Series Speaker Matthew D. Shoulders! Hosted by Marc Mendillo. @MarcMendillo #viruses #Evolution #epigenetics #medicalresearch @NUFeinbergMed @ChemistryMIT
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Big congrats Dr. ⁦@DavidAmici4⁩ ⁦@NUMSTP⁩ on his thesis defense! Stellar body of work (stay tuned for last chap!)—such an absolute joy working with him! Back to M3 now, and I know so many more discoveries coming in the future!! ⁦
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Beautiful work by @CaraveoPiso in @PNASNews on a neuron-astrocyte interplay driven by the octopamine metabolite with relevance to PD -- Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein pnas.org/doi/10.1073/pnas.22…

Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein | PNAS

Octopamine is a well-established invertebrate neurotransmitter involved in fight or flight responses. In mammals, its function was replaced by epin...

pnas.org
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Awesome to see this very nice spotlight in @TrendsGenetics on our recent HAPSTR2 @NatureComms pub by @DavidAmici4 ! cell.com/trends/genetics/ful…
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A link to the original paper: nature.com/articles/s41467-0…

The HAPSTR2 retrogene buffers stress signaling and resilience in mammals

Nature Communications - The recently described protein HAPSTR1 governs cellular stress resilience. Here, the authors discover a mammalian HAPSTR1 paralog, called HAPSTR2, which formed via...

nature.com
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NEW ISSUE ALERT!!! Check out the new issue of Genes & Development @GenesDev, in appreciation of Terri Grodzicker. Read more about her contributions to science communication and publishing here: ➡️genesdev.cshlp.org/content/c…
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Meet a new addition to the HAPSTR family. Findings in @NatureComms from @LurieCancer's @MarcMendillo & @DavidAmici4 may help improve understanding of how #cancer and other diseases hijack stress response programming to survive. news.feinberg.northwestern.e… via @NUFeinbergMed

New Gene Implicated in Cancer, Cellular Stress Response - News Center

Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity.

news.feinberg.northwestern.edu
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Thank you NU news for covering our recent HAPSTR2 publication (see nature.com/articles/s41467-0… ) and great photo of @DavidAmici4 !

The HAPSTR2 retrogene buffers stress signaling and resilience in mammals

Nature Communications - The recently described protein HAPSTR1 governs cellular stress resilience. Here, the authors discover a mammalian HAPSTR1 paralog, called HAPSTR2, which formed via...

nature.com
Northwestern Feinberg School of Medicine@NUFeinbergMed20 Feb 2023
Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to #MolecularStressors, according to a study published in @NatureComms. spr.ly/60133q7Yh

New Gene Implicated in Cancer, Cellular Stress Response - News Center

Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity.

news.feinberg.northwestern.edu
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28th Midwest Stress Response and Molecular Chaperone Conference @NorthwesternU. It was great to see everyone and learn about awesome science @kmo1001001 @HawleLab @dallandrummond @TrumanLab @MarcMendillo @bourboulialab @KravatsLab @WohleverL @TheMarq1 @MedMol @MattooLab and more
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Such an amazing group! And very grateful for all you do— enabling our most exciting work
ACS ABOA Chicago@aboa_chicago20 Jan 2023
In 2022, the Chicago ABOA surpassed its fundraising goal of $575,000! In 2023, we’re looking forward to raising more money, having more fun, and continuing our fight against cancer! Learn how to join the fight at acsaboa.org!
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Yes!! And super excited for the talks, and especially our keynote – the one and only @dallandrummond!!
van Oosten-Hawle lab@HawleLab19 Jan 2023
One of the best meetings to start the year! We are covering topics on Proteostasis & Cancer, Chaperone Function and Regulation, Protein Aggregation, Degradation & Disease, and Stress Responses. 28th Annual Midwest Stress Response and Molecular Chaperone Conference @NorthwesternU
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